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Statins show dramatic drug and cell dependent effects in the brain
Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. view more (2009-10-29)
U of M researchers discover compounds to shrink tumors
Researchers at the University of Minnesota have developed novel anti-cancer drugs to treat solid tumors. These "small molecules" belong to a class of pharmaceutical agents called anti-angiogenics. view more (2006-07-06)
When The Cause Of Depression Is A Medication
Two researchers affiliated with the University of Verona have reviewed the literature on depression caused by medications in an article published in the July-August issue of Psychotherapy and Psychosomatics. Certain medications may contribute to the etiology of depressive symptoms and disorders. Research in this area, however, has been hampered by... view more... (2004-06-22)
Alzheimer's drugs offer modest improvements, equal effectiveness
The Alzheimer's drugs Aricept, Razadyne and Exelon can lead to small improvements in mental functioning and the ability to carry out everyday activities in people with mild to moderate forms of the disease, according to a new review of recent studies. view more (2006-01-25)
Treatments have same target, different responses for lung cancer patients with genetic mutation
The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux). view more (2005-08-17)
Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness. view more (2006-09-18)
Restrictive drug policies often cause schizophrenic patients to discontinue medication
Policies requiring authorization before physicians can prescribe newer medications to schizophrenic patients may be counter-productive. According to a new study, patients in Maine's Medicaid program who found themselves in this situation were 29% more likely to stop or disrupt medication use than patients not subject to the policy. view more (2008-04-01)
Can cancer drugs combine forces?
Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL). view more (2007-08-17)
New Method of Controlled Drug Release
Researchers in Oxford University's Inorganic Chemistry Laboratory have found that they can intercalate a range of pharmaceutically active molecules between the layers of a layered inorganic host. While working on the ion-exchange abilities of a family of inorganic materials known as Layered Double Hydroxides (LDHs), researchers have recognised... view more... (2003-02-11)
Genomics researchers discover protein deficit that causes drug toxicity
Mayo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients. The mechanism decreases a protein and in turn causes certain individuals to metabolize thiopurine drugs differently. view more (2005-07-11)
Cholesterol lowering drugs may prevent degenerative eye disease (macular degeneration)
Statins, the drugs used to lower blood cholesterol, may help prevent the degenerative eye disease known as age related maculopathy or macular degeneration, finds research in the British Journal of Ophthalmology. view more (2003-08-14)
Attitudes to Cannabis are More Tolerant
People are becoming more tolerant of the use of cannabis, but there are still clear limits to what is acceptable in the area of illegal drug-taking, according to new research funded by the ESRC. Views about cannabis have shifted considerably over the past two decades, with 41 per cent of Britons now supporting its legalisation - up from just 12... view more... (2003-07-09)
New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer. view more (2006-12-08)
Value of drugs for pre-osteoporosis exaggerated
A series of recent scientific publications have exaggerated the benefits and underplayed the harms of drugs to treat pre-osteoporosis or "osteopenia" potentially encouraging treatment in millions of low risk women, warn experts in this week's BMJ. view more (2008-01-18)
Who should receive vaccines and antiviral drugs in the event of a flu pandemic?
Since flu vaccine and antiviral drugs are in scarce supply, the WHO recommends that all nations determine in advance which groups of people will be the first to receive these treatments in the event of a flu pandemic. view more (2006-10-17)
Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies. view more (2007-01-09)
Study finds limited options for backup HIV treatment in some developing countries
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies. view more (2007-01-09)
Prescription Dose Changes - Are initially recommended doses too high?
Over 20% of prescription drugs undergo substantial reductions in their recommended dosages, relative to the doses initially recommended, according to two papers published in the August issue of Pharmacoepidemiology and Drug Safety, available online on 14 August 2002. These changes reveal a discrepancy between the dosage information gathered from... view more... (2002-08-13)
New stem-cell findings can help the body to cure itself
Researchers at Karolinska Institutet have identified an important mechanism that regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell. view more (2006-06-16)
Artificial liver for drug tests
If you have hay fever, headaches or a cold, it's only a short way to the nearest chemist. The drugs, on the other hand, can take eight to ten years to develop. view more (2009-06-26)
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