Nogo Receptor Current Events | Nogo Receptor News
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Stopping a receptor called 'nogo' boosts the synapses
New findings about a protein called the nogo receptor are offering fresh ways to think about keeping the brain sharp. view more (2008-03-19)
New hope for stroke patients
If a stroke patient doesn't get treatment within approximately the first three hours of symptoms, there's not much doctors can do to limit damage to the brain. view more (2008-08-26)
Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard immunosuppressant drugs after kidney transplants. Treatment... view more... (2003-04-10)
Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ. view more (2003-03-19)
A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of Dectin-1 as the beta-glucan receptor may also provide... view more... (2004-10-08)
Scientists decipher the formation of lasting memories
Researchers at Karolinska Institutet have discovered a mechanism that controls the brain's ability to create lasting memories. In experiments on genetically manipulated mice, they were able to switch on and off the animals' ability to form lasting memories by adding a substance to their drinking water. view more (2009-11-11)
Myelin suppresses plasticity in the mature brain
Yale School of Medicine researchers report in Science this week genetic evidence for the hypothesis that myelination, or formation of a protective sheath around a nerve fiber, consolidates neural circuitry by suppressing plasticity in the mature brain. view more (2005-09-30)
Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other vertebrates. The genome of the sea- squirt was... view more... (2004-03-31)
Researchers identify taste receptor responsible for caffeine detection
By studying how taste-receptor mutations impact fruit fly behavior, researchers have identified a taste receptor responsible for the detection of caffeine, a bitter compound known to activate certain taste-receptor neurons, as well as impact various aspects of physiology. view more (2006-09-19)
A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported. view more (2005-11-01)
Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals. view more (2007-11-29)
Help for bleeding hearts: new research links a third protein to blood-clotting disorders
Studying receptors on the surface of blood platelets, sticky cells that cause blood to clot, has given one Rockefeller researcher new insight into potential causes and treatments for certain cardiovascular diseases. view more (2006-04-20)
Variant of vitamin D receptor gene linked to melanoma risk
A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gene, called BsmI, may be at an increased risk of... view more... (2008-09-22)
New discovery may help doctors treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta. view more (2005-07-21)
Common herbicides and fibrates block nutrient-sensing receptor found in gut and pancreas
According to new research from the Monell Center and the Mount Sinai School of Medicine, certain common herbicides and lipid-lowering fibrate drugs act in humans to block T1R3, a nutrient-sensing taste receptor also present in intestine and pancreas. view more (2009-10-12)
Matrix fragments trigger fatal excitement
Shredded extracellular matrix (ECM) is toxic to neurons. Chen et al. reveal a new mechanism for how ECM demolition causes brain damage. The study will appear in the December 29, 2008 issue of The Journal of Cell Biology (www.jcb.org). view more (2008-12-30)
Gene variations contribute to aggression and anger in women
Ever wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene. view more (2007-03-12)
Neurons use chemical 'chords' to shape signaling
Researchers have discovered that neurons can use two different neurotransmitters that target the same receptor on a receiving neuron to shape the transmission of a nerve impulse. view more (2008-02-28)
Scientists determine structure of brain receptor implicated in epilepsy and PMT
Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have published new research in the journal Molecular Pharmacology identifying the structure of a receptor in the brain implicated in conditions such as epilepsy and pre-menstrual tension. The same receptor has also been reported to be highly sensitive to... view more... (2008-03-10)
Nicotinic receptors may be important targets for treatment of multiple addictions
For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why. view more (2007-08-16)
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