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Stopping a receptor called 'nogo' boosts the synapses
New findings about a protein called the nogo receptor are offering fresh ways to think about keeping the brain sharp.   view more (2008-03-19)

Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard... view more (2003-04-10)

Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.   view more (2003-03-19)

A Novel Strategy for Combating Aids-Related Fungal Infections
Research at the Sir William Dunn School of Pathology has identified Dectin-1 as the beta-glucan receptor on immune cells. This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of... view more (2004-10-08)

Myelin suppresses plasticity in the mature brain
Yale School of Medicine researchers report in Science this week genetic evidence for the hypothesis that myelination, or formation of a protective sheath around a nerve fiber, consolidates neural circuitry by suppressing plasticity in the mature brain.   view more (2005-09-30)

Stoned sea-squirts
The psychoactive ingredient of the drug cannabis exerts its effects on the human brain by activating proteins known as cannabinoid receptors. Dr. Maurice Elphick of Queen Mary, University of London has uncovered the first evidence that cannabinoid receptors may not be unique to humans and other... view more (2004-03-31)

Researchers identify taste receptor responsible for caffeine detection
By studying how taste-receptor mutations impact fruit fly behavior, researchers have identified a taste receptor responsible for the detection of caffeine, a bitter compound known to activate certain taste-receptor neurons, as well as impact various aspects of physiology.   view more (2006-09-19)

A novel model to pinpoint human androgen receptor targets developed
A novel computational model to pinpoint androgen receptor targets within the human genome was recently reported.   view more (2005-11-01)

Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Help for bleeding hearts: new research links a third protein to blood-clotting disorders
Studying receptors on the surface of blood platelets, sticky cells that cause blood to clot, has given one Rockefeller researcher new insight into potential causes and treatments for certain cardiovascular diseases.   view more (2006-04-20)

New discovery may help doctors treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta.   view more (2005-07-21)

Gene variations contribute to aggression and anger in women
Ever wonder why some women seem to be more ill-tempered than others? University of Pittsburgh researchers have found that behaviors such as anger, hostility and aggression may be genetic, rooted in variations in a serotonin receptor gene.   view more (2007-03-12)

Neurons use chemical 'chords' to shape signaling
Researchers have discovered that neurons can use two different neurotransmitters that target the same receptor on a receiving neuron to shape the transmission of a nerve impulse.   view more (2008-02-28)

Scientists determine structure of brain receptor implicated in epilepsy and PMT
Scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) have published new research in the journal Molecular Pharmacology identifying the structure of a receptor in the brain implicated in conditions such as epilepsy and pre-menstrual tension. The same receptor has... view more (2008-03-10)

Nicotinic receptors may be important targets for treatment of multiple addictions
For years, scientists have known that some people are biologically more susceptible to drug addiction than others, but they have only been able to speculate why.   view more (2007-08-16)

Breast cancer subtypes linked to survival from secondary brain tumors
Screening breast cancers for three receptors could help doctors predict the likely survival of patients with brain metastases.   view more (2008-02-28)

Crucial Factors in Lymphoma Development and Survival Discovered
Researchers at National Jewish Medical and Research Center have discovered an important factor in the development of B-cell lymphomas, one of the fastest growing forms of cancer.   view more (2008-06-24)

Previously unseen switch regulates breast cancer response to estrogen
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, according to research by scientists at Emory University's Winship Cancer Institute.   view more (2008-05-09)

Some antipsychotic drugs may be missing their mark
Drugs that treat depression, schizophrenia and other psychotic conditions and that target a particular protein on brain cells might not be triggering the most appropriate response in those cells, new research suggests.   view more (2008-01-02)

Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage.   view more (2007-04-02)

Targeting nerve growth factor may cure liver cancer
Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the nervous system including brain.   view more (2007-09-19)

Integrins as receptors give insight into rotavirus and diarrhea
Eleven years ago, Dr. Mary Estes of Baylor College of Medicine and her colleagues discovered the first viral enterotoxin, rotavirus NSP4, a toxic protein that affects the intestines, causing diarrhea.   view more (2008-07-01)

UVa Scientists Hot on Trail of Therapies for Deadly Lung Failure
Researchers at the University of Virginia Health System have identified a molecular target, or receptor, for potential drugs to treat acute respiratory distress syndrome (ARDS), a sudden and life-threatening failure of the lung.   view more (2006-02-22)

Specific antagonism lowers blood pressure
High blood pressure (hypertension) is associated with an increased risk of heart attack and stroke, and the frequent use of drugs known as NSAIDs, for example to treat individuals with rheumatoid arthritis, can cause hypertension.   view more (2007-08-17)

HIV accessory protein disables host immunity via receptor-protein intermediary
Researchers at the University of Pennsylvania School of Medicine discovered that an HIV-1 accessory protein called Vpr destroys the host cell's ability to survive by binding to a host receptor.   view more (2006-03-31)
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