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Psst! Coffee drinkers: Fruit flies have something to tell you about caffeine
In their hunt for genes and proteins that explain how animals discern bitter from sweet, a team of Johns Hopkins researchers began by testing whether mutant fruit flies prefer eating sugar over sugar laced with caffeine.   view more (2006-09-19)

Gene therapy reduces cocaine use in rats
Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have shown that increasing the brain level of receptors for dopamine, a pleasure-related chemical, can reduce use of cocaine by 75 percent in rats trained to self-administer it.   view more (2008-04-16)

Improved estrogen reception may sharpen fuzzy memory
Estrogen treatments may sharpen mental performance in women with certain medical conditions, but University of Florida researchers suggest that recharging a naturally occurring estrogen receptor in the brain may also clear cognitive cobwebs.   view more (2008-07-30)

New biomarker predicts effectiveness of breast cancer drugs
University of Cincinnati (UC) researchers have identified a new way to predict when anti-estrogen drug therapies are inappropriate for patients with hormone-dependent breast cancer.   view more (2006-12-08)

New 'Knock-Out' Gene Model Provides Molecular Clues to Breast Cancer
New insights into the role of estrogen receptor in mammary gland development may help scientists better understand the molecular origin of breast cancer, according to new research from the University of Cincinnati (UC).   view more (2007-09-06)

AMD discovery: New hope for treatment of vision loss
Scientists have won a major battle in the fight against age-related macular degeneration, or AMD, a blinding eye disease that affects millions of people. An international team, led by researchers at Sainte-Justine Hospital and the Université de Montréal, has identified the deficient... view more (2008-02-21)

Dartmouth researchers show effects of low dose arsenic on development
A team of Dartmouth Medical School (DMS) researchers has determined that low doses of arsenic disrupt the activity of a hormone critical in development.   view more (2007-11-15)

Overproducing leptin receptors in fat cells may be key to halting weight gain
A new study by researchers at UT Southwestern Medical Center suggests that when fat cells increase in size - as they do during the development of obesity - the cells progressively lose receptors for the hormone leptin, a powerful stimulus for fat burning.   view more (2005-12-01)

Researchers at Vanderbilt-Ingram Cancer Center uncover clue to explain invasive brain tumors
Researchers at the Vanderbilt-Ingram Cancer Center have uncovered a clue to explain the invasive nature of an aggressive kind of brain tumor called glioblastoma multiforme, or gliomas.   view more (2006-01-12)

Major step forward in effective treatment for HIV/AIDS
FROM PROCEEDINGS B OF THE ROYAL SOCIETY ONLINE ACCESS VIA FIRSTCITE FROM: 4 September 2002 New research findings by scientists in Germany* - soon to be published in The Royal Society`s Proceedings B journal - will be of major importance for HIV and AIDS treatment in the future. The findings... view more (2002-08-30)

Scientists Identify Bovine Gene Regulating Milk Production
MTT Agrifood Research Finland and the University of Lie'ge, Belgium, have worked together successfully in locating a gene that regulates total yield and protein and fat content of milk. The scientists found a variation in the growth hormone receptor gene in the bovine chromosome 20. The variation... view more (2003-02-20)

Is Bcl-2 protein a major obstacle in treating colorectal carcinoma?
Apoptosis resistance has been shown to contribute to the development of different cancer entities, such as colorectal carcinoma (CRC).   view more (2008-09-24)

T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).   view more (2007-09-18)

NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of... view more (2008-02-11)

What emotional memories are made of
Both extensive psychological research and personal experiences confirm that events that happen during heightened states of emotion such as fear, anger and joy are far more memorable than less dramatic occurrences.   view more (2007-10-05)

VIP's importance to temperature regulation may be pre-empted by substance P
An elusive neurotransmitter pathway in the skin may have been isolated by University of Oregon researchers, a discovery that, if confirmed, would be a leap forward in understanding how temperature regulation occurs.   view more (2006-10-25)

Making mice with enhanced color vision
Researchers at the Johns Hopkins School of Medicine and their colleagues have found that mice simply expressing a human light receptor in addition to their own can acquire new color vision, a sign that the brain can adapt far more rapidly to new sensory information than anticipated.   view more (2007-03-23)

New treatment mechanisms for schizophrenia
The field of schizophrenia research has come alive with many exciting new potential approaches to treatment. From the introduction of chlorpromazine to the current day, all treatments approved by the U.S. Food and Drug Administration have had, at their core, a single treatment mechanism, the... view more (2008-01-09)

Jefferson Scientists Identify Gene Mutation Potentially Involved in Breast Cancer Initiation
Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia and at the Albert Einstein College of Medicine in New York have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could... view more (2006-06-01)

Neuroscientists Show Insulin Receptor Signaling Regulates Structure and Function of Brain Circuits
A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated for the first time in living animals that insulin receptors in the brain can initiate signaling that regulates both the structure and function of neural circuits.   view more (2008-06-19)

Scientists find one reason why bladder cancer hits more men
Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease. The finding could open the door to new types of treatment with the... view more (2007-04-23)

New role for sugars: Research shows connections between sugar modifications in cells and cancer
In a ground-breaking study published in the top journal, Cell, Dr. James Dennis, senior investigator at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, has discovered a new role for sugars on proteins.   view more (2007-04-06)

Tummy Bug Puzzle Unravelled
The bacterium, Helicobacter pylori, which infects the stomach, causes duodenal ulcer disease and is thought to cause stomach cancer. The question of why the bacteria are only found in the stomach has puzzled scientists for many years. Researchers at the Conway Institute and the Children's Research... view more (2004-05-11)

New insights into the neural basis of anxiety
People who suffer from anxiety tend to interpret ambiguous situations, situations that could potentially be dangerous but not necessarily so, as threatening.   view more (2007-06-04)

A gene for metastasis
Colorectal cancer is one of the most prevalent cancers in the Western world. The tumor starts off as a polyp but then turns into an invasive and violent cancer, which often spreads to the liver.   view more (2007-08-28)

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