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The G allele of the mu-opioid receptor gene is linked to craving for alcohol
The study of genes and their influence on alcohol consumption can operate on many different levels. Some studies examine how genes may interact with the environment, some look specifically at family history of alcohol dependence, and some zero in on "pieces" of genes and their influence... view more (2007-01-04)

A new idea for how anti-aging products delay ripening of fruit and wilting of flowers
When plants encounter ethylene, a gas they also produce naturally as a hormone, the result is softening and ripening in the case of fruit, and wilting and fading in the case of flowers - all of which ethylene promotes.   view more (2008-05-05)

Mayo Clinic researchers challenge sepsis theory
A Mayo Clinic research team has challenged the accepted theory on the cause of sepsis - a condition in which the body's cells generate fever, shock and often death.   view more (2006-02-08)

UCLA study uncovers clues for why Graves' disease attacks the eyes
UCLA researchers have uncovered new clues that may explain why Graves' disease (GD) attacks the muscle tissue behind the eyes, often causing them to bulge painfully from their sockets, as in the late actor Marty Feldman.   view more (2007-03-01)

1 missing gene leads to fruitless mating rituals
Male fruit flies missing a gene for one particular odor receptor become clueless in matters of love, scientists at Duke University Medical Center have discovered.   view more (2008-07-24)

New Mount Sinai research tracks effects of addictive drugs on brain
Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain.   view more (2008-05-16)

Study shows enzyme builds neurotransmitters via newly discovered pathway
The new study describes a pathway-different than the one previously suggested-for the biosynthesis of neurotransmitter lipids, N-acyl ethanolamines (NAEs), which include the endogenous cannabinoid ("endocannabinoid") anandamide.   view more (2006-09-12)

Breastfeeding reduces risk of breast cancer for women who delay childbirth
Breastfeeding can offset the increased risk of invasive breast cancer for women who had their first full-term pregnancy after the age of 25, a study led by researchers at the University of Southern California (USC) suggests.   view more (2007-04-17)

Pre-clinical studies identify novel ways to enhance effect of chemotherapy
Results call for clinical trials with Glivec in combination with other chemotherapy Frankfurt, Germany: Researchers have found that blocking the action of a growth factor on tumour stroma cells[1] increases the uptake of cancer drugs by the tumour. The findings could be crucial for efforts to make... view more (2002-11-17)

Benefit of chemotherapy in breast cancer depends on estrogen-receptor status
When it comes to chemotherapy treatment for women whose breast cancer has spread to their lymph nodes, the estrogen status of their tumors matters.   view more (2006-04-12)

Neuronal Receptor Response May Help Explain Alzheimer's Memory Loss
Based on laboratory research, scientists at Georgetown University Medical Center have a new theory as to why people with Alzheimer's disease have trouble performing even the simplest memory tasks, such as remembering a family member's name.   view more (2006-02-13)

Joslin-led study reveals findings on how insulin-producing beta cells grow and function
Joslin-led study reveals findings on how insulin-producing beta cells grow and function   view more (2006-04-24)

Contribution of cholesterol transporter to vascular disease
Low-density lipoprotein (LDL), a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online this week in EMBO reports.   view more (2007-10-26)

Gene against bacterial attack unravelled
Dutch researcher Joost Wiersinga from AMC Medical Centre in Amsterdam has unravelled a genetic defence mechanism against the lethal bacteria Burkholderia pseudomallei. The research is the next step towards a vaccine against this bacterium suitable for bioweapons.   view more (2008-10-29)

Protein Plays Critical Role in Heart Failure in Both the Heart and Adrenal Gland
A protein that plays an important regulatory role in heart failure in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have found.   view more (2005-11-16)

EARLY PROMISE FOR TREATMENT OF PULMONARY HYPERTENSION (pp 1113, 1119)
Encouraging results of a randomised trial in this week’s issue of THE LANCET suggest that the drug bosentan could play an important future role in the treatment of pulmonary hypertension. Pulmonary hypertension (raised pressure in the blood vessels supplying the lungs) causes thickening of... view more (2001-10-03)

Opioids and cannabinoids influence mobility of spermatozoids
A PhD thesis from the University of the Basque Country has concluded that there are opioid and cannabinoid receptors in human sperm and that these influence the mobility of spermatozoid.   view more (2008-06-23)

Cocaine: How addiction develops
Permanent drug seeking and relapse after renewed drug administration are typical behavioral patterns of addiction. Molecular changes at the connection points in the brain's reward center are directly responsible for this.   view more (2008-08-22)

UK researcher finds 'switching' compound for angiogenesis
For the second time in a week Dr. Jayakrishna Ambati, UK HealthCare physician and associate professor and vice chair of the Department of Ophthalmology and Visual Sciences, announced a discovery from his lab that will affect the future of macular degeneration treatment and research.   view more (2006-02-03)

Research suggests aspirin helps combat cataracts
Ongoing research in the School of Animal and Microbial Sciences (AMS) at the University of Reading has helped to clarify the process of cataract, the largest cause of blindness in the world. Professor James Crabbe and his team in AMS have targeted the importance of non-steroidal anti-inflammatory... view more (2004-06-03)

Researchers find docking sites for glucocorticoid receptor and Hsp90
University of Oregon researchers have identified protein interactions that regulate the response of cells to steroid hormones. The discovery, they say, could lead to new ways to boost the effectiveness and reduce undesired side effects of steroid-hormone treatments and cancer drugs.   view more (2006-11-21)

EGF receptor activation prevents microbes from going more than skin deep
Our skin not only serves as a physical barrier against infection but skin cells themselves can mount an immune response to kill invading microbes by producing antimicrobial polypeptides (AMPs).   view more (2006-06-16)

New clues to how major weight-loss drugs work
Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve... view more (2006-07-20)

Tendency to hair loss inherited from the mother
The male sex hormones really do seem to play a decisive role in causing hair loss in men. This has been confirmed by scientists from the universities of Bonn and Düsseldorf. Their studies show that specific changes in the genetic 'construction manual' of the androgen receptor may result in... view more (2005-05-20)

“Shooting the messenger” to tackle autoimmune diseases
AIDS and other autoimmune diseases could be tackled with a range of new drugs that stop cells recognising certain chemical messages in blood, says Dr Gerry Graham from the Glasgow-based Institute for Cancer Research speaking at the BA Festival of Science today [3 September 2001]. Autoimmune... view more (2001-08-30)
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