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Depression diversity: Brain studies reveal big differences among individuals
Depressed people may have far fewer of the receptors for some of the brain's "feel good" stress-response chemicals than non-depressed people, new University of Michigan Depression Center research shows.   view more (2008-05-08)

Study raises questions about prostate cancer therapies targeting IGF-1
Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators... view more (2008-05-01)

Discovery could lead to better control of hemorrhagic fever viruses
Researchers report discovering the receptor through which a group of life-threatening hemorrhagic fever viruses enter and attack the body's cells, and show that infection can be inhibited by blocking this receptor.   view more (2007-02-08)

Going from ulcers to cancer
Researchers have uncovered a big clue as to why some of the bacteria that cause stomach ulcers pose a greater risk for serious problems like stomach cancer than others; it turns out these bacteria can exploit the surrounding stomach cells to protect them from the immune system.   view more (2008-08-25)

Picking apart how neurons learn
Johns Hopkins researchers have used mouse mutants to define critical steps involved in learning basic motor skills. The study focuses on the behavior of two proteins and the specific steps they take to control a neuron's ability to learn by adapting to signals from other nerve cells.   view more (2006-03-30)

'Knocking Out' Cell Receptor May Help Block Fat Deposits in Tissues, Prevent Weight Gain
University of Cincinnati (UC) pathologists have identified a new molecular target that one day may help scientists develop drugs to reduce fat transport to adipocytes (fat cells) in the body and prevent obesity and related disorders, like diabetes.   view more (2007-10-26)

Leading cause of death in 'preemies' might be controlled by resetting a molecular switch
Blocking signals from a key molecular receptor that normally switches on the intestine's immune response but instead becomes too intense in the presence of stress and toxins may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature newborns.   view more (2007-12-03)

How does the opioid system control pain, reward and addictive behavior?
The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).   view more (2007-10-15)

Inflammation markers identify fatigue in breast cancer survivors
Researchers at the University of California, Los Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research.   view more (2006-05-01)

Researchers find predictor of mortality in cardiac patients
Researchers at SUNY Downstate Medical Center in Brooklyn have determined that low levels of a protein in the blood is a predictor of cardiac death in patients with coronary artery disease.   view more (2007-02-21)

Insects evolved radically different strategy to smell
Darwin's tree of life represents the path and estimates the time evolution took to get to the current diversity of life. Now, new findings suggest that this tree, an icon of evolution, may need to be redrawn.   view more (2008-04-14)

Apelin to rescue diabetics
Sugar is naturally present in the blood in the form of glucose and is stored in the liver or adipose tissue (fat) thanks to the action of insulin. Glucose is stored or directly used to ensure satisfactory function of the heart, brain and so on according to the body's demands.   view more (2008-11-05)

UCSD study of nuclear receptors could change anti-inflammatory treatments
Several nuclear receptor proteins appear to overlap in their ability to exert anti-inflammatory effects, according to new research by scientists at the University of California, San Diego (UCSD).   view more (2005-09-09)

Pheromones Identified that Trigger Aggression between Male Mice
A family of proteins commonly found in mouse urine is able to trigger fighting between male mice, a study in the Dec. 6, 2007, issue of Nature has found.   view more (2007-12-06)

Hope for arthritis, heart attack, stroke relief found in unique 'acid active' receptor
he fact that arthritis pain and inflammation regularly comes and goes despite drug and other interventions "suggests that additional pathways can rekindle arthritic responses," according to researchers at the University of Texas Medical Branch in Galveston.   view more (2005-10-24)

Abnormal immune cells may cause unprovoked anaphylaxis
Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.   view more (2007-11-12)

Possible birthplace of malignant brain tumors identified
Researchers have found that abnormal stimulation of a cellular trigger that normally regulates replenishment of brain cells in adults causes invasive tumor-like growths in mice.   view more (2006-07-20)

Minor mutations in avian flu virus increase chances of human infection
The H5N1 avian influenza virus, commonly known as "bird flu," is a highly contagious and deadly disease in poultry.   view more (2006-03-20)

Dartmouth researchers find that low doses of arsenic have broad impact on hormone activity
Dartmouth Medical School investigators are learning more about how low doses of arsenic, such as the levels found in drinking water in many areas of the United States, affect human physiology.   view more (2006-12-05)

Novel mechanism for long-term learning identified by Carnegie Mellon researchers
Practice makes perfect - or at least that's what we're told as we struggle through endless rounds of multiplication tables, goal kicks and piano scales - and it seems, based on the personal experience of many, to be true.   view more (2008-01-04)

Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
Identification of the molecular cues governing cell migration is of major importance for the understanding of tissue and organ development and for therapy in cases of diseases resulting from aberrant cell movement. Primordial Germ Cell (PGC) migration is a useful model for studying directional cell... view more (2002-11-27)

Why don't painkillers work for people with fibromyalgia?
People who have the common chronic pain condition fibromyalgia often report that they don't respond to the types of medication that relieve other people's pain.   view more (2007-09-28)

PET imaging confirms link between receptor levels and cocaine abuse
Using positron emission tomography (PET), researchers have established a firm connection between a particular brain chemistry trait and the tendency of an individual to abuse cocaine and possibly become addicted, suggesting potential treatment options.   view more (2006-07-12)

LA BioMed research finds simpler way to assess breast cancer risk
A new, simpler model for predicting breast cancer risk in postmenopausal women appears to be as accurate as a more complicated method currently used to decide if women would benefit from medication to reduce their risk of getting cancer, according to research published today in the Journal of the... view more (2007-11-14)

Do 'light' cigarettes deliver less nicotine to the brain than regular cigarettes?
For decades now, cigarette makers have marketed so-called light cigarettes - which contain less nicotine than regular smokes - with the implication that they are less harmful to smokers' health. A new UCLA study shows, however, that they deliver nearly as much nicotine to the brain.   view more (2008-09-29)
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