Nucleic Acid Current Events | Nucleic Acid News
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Carnegie Mellon scientists create PNA molecule with potential to build nanodevices
For the first time, a team of investigators at Carnegie Mellon University has shown that the binding of metal ions can mediate the formation of peptide nucleic acid (PNA) duplexes from single strands of PNA that are only partly complementary. view more (2005-10-04)
Accelerated evolution converts RNA enzyme to DNA enzyme in vitro
This 'evolutionary conversion' provides a modern-day snapshot of how life as we understand it may have first evolved out of the earliest primordial mix of RNA-like molecules-sometimes referred to as the "pre-RNA world"-into a more complex form of RNA-based life (or the "RNA world") and eventually to cellular life based on DNA... view more... (2006-03-28)
Yale study explains complex infection fighting mechanism
Yale School of Medicine researchers report in Nature Immunology how infection fighting mechanisms in the body can distinguish between a virus and the healthy body, shedding new light on auto immune disorders. view more (2006-01-11)
Immune system response to viral DNA is unique
The human body has a unique immune system response to foreign DNA, suggesting that DNA viruses and RNA viruses are detected by different mechanisms. view more (2006-01-25)
New data supports a non-invasive approach to routine prenatal genetic testing
Research studies demonstrating the viability of an approach to routinely detect the presence of fetal DNA in a mother's blood to accurately diagnose or rule out genetic defects — as early as the first trimester — was presented today at the 27th Annual Meeting of the Society for Maternal-Fetal Medicine being held in San Francisco. view more (2007-02-12)
Controversial findings help explain evolution of life
Chemists at Oregon State University have pioneered a controversial theory about how supposedly-stable DNA bases can be pushed into a "dark state" in which they are highly vulnerable to damage from ultraviolet radiation - an idea that has challenged some of the most basic concepts of modern biochemistry. view more (2006-04-07)
Simple membranes could have allowed nutrients to pass into primitive cells
When the first cells developed, how could they bring molecules from the environment into their living interior without the specialized structures found on the modern cell membrane? view more (2008-06-05)
STN International Launches New Biosequence Database
Nucleotide and amino acid sequence database jointly produced by FIZ Karlsruhe and WIPO released Karlsruhe, Germany - FIZ Karlsruhe, one of Europe's leading providers of information services, and European partner of premier science and technology online service STN International, has announced the launch of the PCTGEN database, an important new... view more... (2003-03-07)
Epilepsy drug may help Alzheimer's patients
A popular epilepsy drug may also be beneficial in patients with Alzheimer's disease (AD), according to a new study to be published on October 27 in the Journal of Experimental Medicine. The anti-seizure drug valproic acid improved memory and reduced brain lesions in mice with an AD-like disease. view more (2008-10-27)
No Increased Risk of Miscarriage From Folic Acid Supplements (p 796)
Women who consume folic acid supplements around the time of conception are not at an increased risk of miscarriage, conclude authors of a population-based study published in this weke’s issue of THE LANCET. Although it is well known that folic acid supplements can reduce the risk of infant neural-tube defects (NTDs), its effects on other... view more... (2001-09-05)
Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
The distribution of the four nucleotides along the DNA sequence encodes the genetic information in living systems. However, do nucleic acids possess other attributes that contribute to their biological functions? view more (2007-03-14)
Folic acid deficit increased risk of miscarriage in early pregnancy
Low levels of folic acid in plasma have been associated with an increased risk of miscarriage in a study published in Journal of the American Medical Association lately. On the other hand, no connection was found between high levels of folic acid and increased risk of miscarriage. In the US folic acid is added to flour to prevent pregnant women... view more... (2002-10-22)
Evidence for warts treatments is weak
Apart from topical treatments containing salicylic acid, there is currently no clear evidence that any other treatments for warts are more effective, say researchers in this week’s BMJ. view more (2002-08-28)
'Fishy' clue helps establish how proteins evolve
Three billion years ago, a "new" amino acid was added to the alphabet of 20 that commonly make up proteins in organisms today. Now researchers at Yale and the University of Tokyo have demonstrated how this rare amino acid - and, by example, other amino acids - made its way into the menu for protein synthesis. view more (2009-01-28)
Genome of PURAC's lactic acid-producing micro-organism completed by Greenomics™
PURAC and Greenomics™ (Plant Research International B.V.) announced the completion of the whole-genome sequencing of a production strain of PURAC that produces high amounts of lactic acid. Greenomics™ conducted the shotgun cloning and high quality sequencing of the genome up to a zero-gap situation. The closed genome is accompanied by... view more... (2002-05-14)
Food Fortification With Vitamin B12 In Addition To Folic Acid Could Reduce Risk Of Cardiovascular Disease (p 227)
Authors of a research letter in this week's issue of THE LANCET conclude that vitamin B12 in addition to folic acid should be used to fortify food to lower concentrations of the blood protein homocysteine, thereby potentially reducing the risk of cardiovascular disease. Mandatory fortification of grain foods with folic acid has been in place in... view more... (2002-01-17)
Kiss goodbye to biopsies
JUST a drop of blood or urine might be enough to reveal if a patient has cancer, what type it is and whether it`s treatable. "One day, there could be one biochip for analysing all cancers," says Christian Piepenbrock, head of bioinformatics at Epigenomics of Berlin. Its technique distinguishes... view more... (2002-03-06)
Photonic crystal biosensors detect protein-DNA interactions
Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors are suitable for the rapid identification of inhibitors of protein-nucleic acid and protein-protein interactions. view more (2008-09-24)
Powerful mold-inhibiting bacteria patented
Bacteria that produce lactic acid have been used for thousands of years to preserve food. Some lactic acid bacteria also produce several other mold-inhibiting substances and are therefore of special interest to agriculture and the foodstuffs industry. This is demonstrated in a dissertation by Jörgen Sjögren from the Swedish University of... view more... (2005-04-08)
Folic Acid Supplements Not Linked To Multiple Births (p 380)
Results of a Chinese population-based study in this week's issue of THE LANCET provide strong evidence that women who take folic acid supplements during pregnancy do not have an increased likelihood of having a multiple birth. Folic acid supplements are recommended for women of childbearing age to prevent neural tube defects-such as spina bifida... view more... (2003-01-29)
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