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Off-label Prescribing Current Events | Off-label Prescribing News | 10
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Study shows digitalis safe in patients with common form of heart failure Despite a widely held belief that the heart drug digitalis shouldn't be given to patients with diastolic heart failure, a new analysis shows it is relatively safe. view more (2006-07-26)
New data show treatment of multiple sclerosis with AVONEX enhances quality of life Results from a one-year prospective, observational study conducted to determine the impact of beginning treatment with AVONEX on MS patients' overall quality of life (QoL) were announced today. view more (2008-04-17)
Carnegie Mellon study offers new clues about memory A study conducted by researchers at Carnegie Mellon University and the University of Pittsburgh involving an amnesia-inducing drug has shed light on how we form new memories. view more (2006-07-19)
By amplifying cell death signals, scientists make precancerous cells self-destruct When a cell begins to multiply in a dangerously abnormal way, a series of death signals trigger it to self-destruct before it turns cancerous. Now, in research to appear in the August 15 issue of Genes & Development, Rockefeller University scientists have figured out a way in mice to amplify... view more (2008-08-18)
Study identifies causes of bone loss in breast cancer survivors Osteoporosis is a growing concern among breast cancer survivors and their doctors, because certain cancer drugs can cause bone loss. view more (2008-11-20)
Protect and Serve - Lawyer says US physicians should put medical ethics before patriotic duty US military physicians involved in the "war on terror" should put their responsibility for the care of patients before duty to their country, according to an article published today in BMC Medical Ethics. Jerome A Singh, a senior lecturer in law and bioethics at the Howard College School... view more (2003-07-31)
Potential treatment option for severe emphysema under study Emory University researchers are participating in a nationwide study to explore an investigational treatment for advanced widespread emphysema. view more (2008-09-25)
Clinical judgement still counts strongly alongside genetic testing Suggestions that genetic tests are taken more into account than a doctor's clinical judgement are dismissed in new research sponsored by the ESRC and published as part of Social Science week. And clinicians do not adopt a 'blunderbuss' or 'grape-shot' approach. Appropriate tests are ordered in the... view more (2004-06-22)
Heart experts call for urgent action to implement new findings on cholesterol-lowering treatment Research reported in (Saturday 6 July) Lancet is set to revolutionise the way cholesterol-lowering drugs are prescribed. It shows that using "statin" drugs to lower blood cholesterol levels protects a far wider range of people at risk of heart attacks and strokes than had previously been... view more (2002-06-28)
Obese children show early signs of heart disease Children who are obese or who are at risk for obesity show early signs of heart disease similar to obese adults with heart disease, a study by researchers at Washington University School of Medicine in St. Louis has found. view more (2007-10-18)
Hungry microbes share out the carbon in the roots of plants Sugars made by plants are rapidly used by microbes living in their roots, according to new research at the University of York, creating a short cut in the carbon cycle that is vital to life on earth. view more (2007-10-19)
COPAXONE® may repair nerve damage in Multiple Sclerosis patients Clinical research data published in the December issue of Multiple Sclerosis provided evidence that COPAXONE® (glatiramer acetate injection) may offer protection from axonal injury and induced neuronal metabolic recovery in patients with relapsing remitting multiple sclerosis (RRMS). view more (2005-11-15)
New nanotech products hitting the market at the rate of 3-4 per week New nanotechnology consumer products are coming on the market at the rate of 3-4 per week, a finding based on the latest update to the nanotechnology consumer product inventory maintained by the Project on Emerging Nanotechnologies (PEN). view more (2008-04-25)
Millisecond brain signals predict response to fast-acting antidepressant Images of the brain's fastest signals reveal an electromagnetic marker that predicts a patient's response to a fast-acting antidepressant, researchers have discovered. view more (2008-10-03)
Curacyte receives FDA clearance for clinical trial of PHP as an adjunct to IL-2 cancer therapy Munich, Germany, July 1st, 2003 - Curacyte AG, a Munich-based drug development company focused on novel treatments of inflammatory diseases, thrombotic disorders and cancer has announced today that its US IND for conducting a Phase I study with Pyridoxalated Hemoglobin Polyoxyethylene (PHP) as an... view more (2003-07-01)
Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score. view more (2007-05-22)
Aspirin may be less effective heart treatment for women than men A new study shows that aspirin therapy for coronary artery disease is four times more likely to be ineffective in women compared to men with the same medical history. view more (2007-04-30)
Antidepressants linked to lower child suicide rates esearchers report an inverse relationship between antidepressant prescriptions and the rates of suicide in children and adolescents - a finding that contradicts the Food and Drug Administration's "black box" warning for selective serotonin reuptake inhibitor medications, also known as... view more (2006-11-02)
Women may be able to 'take break' from osteoporosis drug without losing benefit Most postmenopausal women who took the osteoporosis drug alendronate for 5 years and then stopped did not have an increased risk for nonvertebral fractures in the next 5 years, suggesting the medication has a lasting effect, according to a study in the December 27 issue of JAMA. view more (2006-12-27)
Brief, high-dose steroid treatment offers extended relief to giant cell arteritis patients A new study offers both hope and a practical treatment option for patients with giant cell arteritis (GCA). Researchers from Emory University and the Mayo Clinic have found that by treating newly diagnosed GCA patients with just three days of a high-dose intravenous steroid, patients relapsed less... view more (2006-10-04)
Home testing kit could help identify 'hidden' caffeine in beverages If you've ever wondered whether your favorite coffee, tea or soda contains caffeine - despite its decaf label or the absence of caffeine on the ingredient list - then you may soon be able to test the beverage yourself. view more (2006-05-11)
Depression in MS patients clue to better treatment Depression increases in some patients with multiple sclerosis over time, according to neuropsychologists, and this research finding could help reduce depression in patients and aid in better treatment strategies. view more (2006-05-18)
Similar outcomes for patients with ACS treated with different anticoagulant regimens Patients with acute coronary syndromes such as unstable angina who were undergoing an invasive treatment and received one of three anticoagulant regimens did not have significant differences in the rates of ischemia or death after one year. view more (2007-12-05)
EU joint effort leads to better cancer diagnosis in northern Italy Since March 16, one of the most important drugs used primarily to diagnose cancer was made available for commercial production and distribution in some hospitals and treatment centres in northern Italy. The availability of the drug, 18F-Fludeoxyglucose (18F-FDG), is the result of a joint agreement... view more (2004-04-27)
Report issued on outbreak of serious eye infection linked with use of certain contact lens solution Researchers have additional information concerning the recent outbreak of the corneal infection Fusarium keratitis, which was associated with use of a specific contact lens solution. view more (2006-08-23)
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