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Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis?
A specific variation in the glucocorticoid receptor gene is associated with lung disease progression in cystic fibrosis, research published this week in the online open access journal Respiratory Research reveals.   view more (2007-11-29)

Memantine appears effective and safe in moderate to severe Alzheimer's disease
Memantine, a drug approved for the treatment of Alzheimer disease, appears safe and effective in patients with moderate to severe cases of the condition, according to a study in the January issue of Archives of Neurology.   view more (2006-01-10)

Aspirin -- just for men?
First it was an apple, now it is an aspirin a day that may keep the doctor away. Aspirin has become standard for heart attack prevention, but research published in the online open access journal BMC Medicine suggests that this may really be a man's drug.   view more (2007-10-18)

Assessing therapy for treatment of depression in the elderly
Depression is the most common psychiatric disorder amongst older adults, one and a half times more frequent than dementia. Explained Ken Laidlaw: "Low expectations regarding treatment success and a fear of possible negative side-effects from anti-depressant medication, often leads to doctors... view more (2000-01-20)

Paediatric research should take centre stage (pp 732, 803)
An editorial in this week's issue of THE LANCET comments on the recent UK Government's announcement of a new initiative to encourage the development of more medicines designed specifically for use in children. "Off-label" use is common in paediatrics, which can mean that drugs have not... view more (2004-08-25)

Gold nanostar shape of the future
Rods, cones, cubes and spheres - move aside. Tiny gold stars, smaller than a billionth of a meter, may hold the promise for new approaches to medical diagnoses or testing for environmental contaminants.   view more (2008-11-07)

Popular pill for inducing labor found effective, but concerns remain
A popular anti-ulcer pill used around the world for inducing labor and preventing post-delivery bleeding appears to be as effective as more expensive drugs but still must be used with caution, according to an updated systematic review of studies.   view more (2006-04-19)

A rainbow of methods promises insights into biological processes and diseases
Physical alterations of DNA in chromosomes can cause serious diseases such as Down syndrome, Prader-Willi syndrome, or cancer.   view more (2007-05-02)

WIDE VARIATION OF ANTIBIOTIC USE IN EUROPE (p 1851)
The type and frequency of antibiotic use varies greatly throughout Europe, according to authors of a research letter in this week's issue of THE LANCET. The use of antibiotics has not been assessed on a European scale, although information on use could be helpful in preventing antimicrobial... view more (2001-06-06)

Using brain scans, researchers find evidence for a two-stage model of human perceptual learning
Using advanced brain imaging techniques, researchers at Georgetown University Medical Center have watched how humans use both lower and higher brain processes to learn novel tasks, an advance they say may help speed up the teaching of new skills as well as offer strategies to retrain people with... view more (2007-03-15)

Breakthrough MS treatment doesn't reach US patients
Many US multiple sclerosis (MS) patients aren't receiving the latest drug therapies, according to research published in the online journal BMC Medicine. Immunomodulatory agents (IMAs) could slow the progress of the disease, but are only prescribed in a minority of cases, and mostly by neurologists.   view more (2007-04-05)

World-wide warning of highly drug-resistant tuberculosis
New forms of highly drug-resistant tuberculosis are emerging and action must be taken soon before they become widespread globally.   view more (2006-09-15)

How to Understand Requirements of Wide Audience End-Users in the era of 3G and Digital TV
On April 6th Tuure Tuunanen, MSc. (econ), defended the doctoral dissertation "Requirements Elicitation for Wide Audience End-Users" at the Helsinki School of Economics. The opponent was Professor Kalle Lyytinen (Case Western Reserve University, USA) and the custos Professor Timo Saarinen (Helsinki... view more (2005-04-06)

UK facing costly "epidemic" of heart pump disturbance (atrial fibrillation)
The UK is facing a costly "epidemic" of a heart condition known as atrial fibrillation, reveals research in Heart. Conservative estimates suggest that costs have almost doubled in five years, soaring to over £500 million in 2000.   view more (2004-02-13)

Can longer consultations really save time and resources?
It has been argued that increasing the length of general practice consultations will save time and resources. Yet two letters in this week's BMJ suggest that longer consultations may lead to higher health service costs and might necessitate redeployment of pharmacists. Phil Wilson and colleagues... view more (2002-07-10)

Hopkins scientists uncover 'tags' that force proteins to cell surface
Johns Hopkins scientists have discovered internal "shipping labels that allow - and perhaps force - hundreds if not thousands of proteins to get to the surface of cells and stay there.   view more (2005-09-23)

Doctors may be giving the wrong dosage of adrenaline in an emergency because of labelling
A new study by Cambridge University reveals that doctors treating life-threatening emergencies such as allergy attacks may give the wrong dosage of adrenaline (epinephrine) because of confusing labelling.   view more (2008-01-02)

Children with both autism and ADHD often bully, parents say
Children with both autism and attention deficit or attention deficit hyperactivity disorders are four times more likely to bully than children in the general population, according to a study released today in the journal, Ambulatory Pediatrics.   view more (2007-05-18)

25,000 needless deaths each year due to failure to tackle blood clots in hospital
Up to 25,000 people may die needlessly each year due to the failure to prevent blood clots known as venous thromboembolisms (VTE) in UK hospitals, say experts in this week's BMJ.   view more (2007-05-18)

Risks of gastrointestinal ulcers linked to aspirin use might outweigh its benefits for the heart
Doctors should consider whether patients are at high risk of stomach ulcers before prescribing aspirin treatment.   view more (2006-09-20)

Medical profession attempts to "clean up" relations with drug industry
As entanglement between doctors and drug grows, a two-part article by journalist Ray Moynihan in this week’s BMJ explores the brewing conflicts at one of the world’s leading medical institutions over how to redefine relations with big pharmaceutical companies.   view more (2003-05-28)

Taking the pulse of Europe's e-health market
Are Europe's hospitals equipped to meet e-health opportunities? This type of issue was covered by the Health Information Network Europe (HINE) in the largest ever survey of hospitals in Europe, just one of a range of studies it offers members.   view more (2005-03-18)

EMPTY FRIDGES PREDICT POOR HEALTH OF OLDER PEOPLE (p 563)
Elderly people with empty refrigerators are more likely to be readmitted to hospital after assessment compared with patients with adequate refrigerator content, according to a research letter published in this week's issue of THE LANCET. Charles-Henri Rapin and colleagues from Geneva University... view more (2000-08-09)

Millions wasted on blood pressure tablets
Millions of dollars are being spent unnecessarily each year on treatments for high blood pressure says research published this week in BMC Health Services Research. Vast amounts could be saved if doctors prescribed thiazides, the recommended and cheapest drugs, rather than expensive alternatives.... view more (2003-08-29)

Drug-Resistant Bacteria Patterns in Intensive Care Units Changing Nationally
A dangerous drug-resistant bacterium is becoming more prevalent in many intensive care units, according to an article in the Feb. 1 issue of Clinical Infectious Diseases, now available online.   view more (2006-01-06)
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