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Human ES cells progress slowly in myelin's direction
Scientists from the University of Wisconsin, USA, report in the journal Development the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for both basic and clinical research. view more (2009-04-09)
Mimicking a human disease in mice: a new model for the Parkinson related illness multiple system atrophy
In this month`s issue of EMBO Reports Kahle et al. describe how they genetically engineered a mouse to show pathological symptoms similar to those of human patients suffering from the neural disease Multiple System Atrophy (MSA), also known as Shy-Drager-Syndrome. The model could help researchers to develop and test new efficient drugs against... view more... (2002-06-06)
Neural stem cell differentiation factor discovered
Neural stem cells represent the cellular backup of our brain. These cells are capable of self-renewal to form new stem cells or differentiate into neurons, astrocytes or oligodendrocytes. view more (2009-06-30)
MS study offers theory for why repair of brain's wiring fails
Scientists have uncovered new evidence suggesting that damage to nerve cells in people with multiple sclerosis accumulates because the body's natural mechanism for repair of the nerve coating called "myelin" stalls out. view more (2009-07-01)
Statins have unexpected effect on pool of powerful brain cells
Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia. view more (2008-07-07)
New therapeutic targets for neurodegenerative diseases
The focus of work in the Neurosciences Department's Neurobiology Laboratory at the University of the Basque Country's Faculty of Medicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses - those that affect the brain and the spinal cord. view more (2007-05-11)
One size does not fit all
Statins, a commonly prescribed class of drugs used by millions worldwide to effectively lower blood cholesterol levels, may actually have a negative impact in Multiple Sclerosis (MS) patients treated with high daily dosages. view more (2009-05-26)
Study finds gene related to brain development and function plays causal role in schizophrenia
According to a new study conducted by researchers at Mount Sinai School of Medicine, variations of a gene related to brain development and function-OLIG2-may play a causal role in the development of schizophrenia, a hereditary psychiatric disorder with no known biological cause. view more (2006-08-16)
Mice models developed at UCSD to benefit patients with multiple system atrophy
Researchers at the University of California, San Diego (UCSD) School of Medicine have developed a series of transgenic mouse models of multiple system atrophy, a progressive, fatal neurological disorder. view more (2005-11-17)
Stem cell therapy for spinal injury
Researchers at Karolinska Institutet have shown how the transplantation of stem cells improves recovery from spinal injury. However, a painful condition can also develop, which can be prevented if the stem cells are supplemented with a certain gene that controls their maturing process. The results are important for planning of stem cell therapy... view more... (2005-02-13)
New clue into how brain stem cells develop into cells which repair damaged tissue
The joint research, funded by the National Multiple Sclerosis Society and the UK MS Society as well as the National Institutes of Health and Howard Hughes Medical Institute, was conducted by scientists at the University of California San Francisco (UCSF) and University of Cambridge and was published today (01 July) in the journal Genes and... view more... (2009-07-02)
Breakdown of Myelin Implicated in Alzheimer's, UCLA Research Shows
Wisdom comes with age (doesn't it?), but not without a process that takes place in the brain called myelination. Myelin is the fatty sheath that coats the axons of the nerves, allowing for efficient conduction of nerve impulses. view more (2007-05-14)
Research suggests new treatment approaches for glaucoma
New research from Children's Hospital Boston and the Massachusetts Eye and Ear Infirmary (MEEI) may help explain how glaucoma causes blindness, revealing the chain of cellular and molecular events that ultimately damage the optic nerve, preventing visual information from traveling from the eye to the brain. view more (2006-12-06)
Study establishes safety of spinal cord stem cell transplantation
Transplanting human embryonic stem cells does not cause harm and can be used as a therapeutic strategy for the treatment of acute spinal cord injury. view more (2006-07-20)
UCLA Research Implicates Myelin in Early Evolution of Huntington's Disease
Last month, Dr. George Bartzokis, director of the UCLA Memory Disorders and Alzheimer's Disease Clinic, suggested in the journal Alzheimer's & Dementia that the breakdown of a type of myelin that develops late in life promotes the buildup of toxic amyloid plaques long associated with Alzheimer's disease. view more (2007-06-12)
MIT identifies cells for spinal-cord repair
A researcher at MIT's Picower Institute for Learning and Memory has pinpointed stem cells within the spinal cord that, if persuaded to differentiate into more healing cells and fewer scarring cells following an injury, may lead to a new, non-surgical treatment for debilitating spinal-cord injuries. view more (2008-07-22)
Potential new treatment strategy for Alzheimer's disease and other brain and spinal cord damage
A study led by researchers at the San Francisco VA Medical Center and the University of North Carolina, Chapel Hill has identified several new compounds that could play a role in preventing or treating Alzheimer's disease and other degenerative conditions of the nervous system. view more (2006-05-19)
New UW study offers strategy for treatment of fatal nervous system disorder
Working with mice, University of Wisconsin-Madison researchers have developed the basis for a therapeutic strategy that could provide hope for children afflicted with Krabbe's disease, a fatal nervous system disorder. view more (2005-12-13)
OHSU researchers discover potential mechanism to repair brain damage linked to MS
Oregon Health & Science University researchers have identified some of the key factors that prevent the repair of brain damage caused by multiple sclerosis (MS), complications of premature birth, and other diseases and conditions. view more (2005-08-08)
Brain works more chaotically than previously thought
The brain appears to process information more chaotically than has long been assumed. This is demonstrated by a new study conducted by scientists at the University of Bonn. view more (2007-02-28)
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