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Opioid Current Events | Opioid News | 2

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Depression diversity: Brain studies reveal big differences among individuals
Depressed people may have far fewer of the receptors for some of the brain's "feel good" stress-response chemicals than non-depressed people, new University of Michigan Depression Center research shows.   view more (2008-05-08)

'Runner's high' may also strengthen hearts
Endorphins and other morphine-like substances known as opioids, which are released during exercise, don't just make you feel good -- they may also protect you from heart attacks, according to University of Iowa researchers.   view more (2007-11-09)

New guideline for prescribing opioid pain drugs published
A national panel of pain management experts representing the American Pain Society (APS) and the American Academy of Pain Medicine (AAPM) has published the first comprehensive, evidence-based clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.   view more (2009-02-09)

Medication appears effective in treating teen heroin addiction
In a comparison of two drugs prescribed to treat teenagers dependent on heroin and other opioids, the drug buprenorphine was more effective, especially in treatment retention.   view more (2005-10-04)

New brain-chemistry differences found in depressed women
A new brain study finds major differences between women with serious depression and healthy women in a brain-chemical system that's crucial to stress and emotions.   view more (2006-11-07)

How does the opioid system control pain, reward and addictive behavior?
The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).   view more (2007-10-15)

Abrupt withdrawal of drugs to prepare for surgery can be dangerous
(Editorial: The risks of interrupting drug treatment before surgery) Abruptly stopping drug treatments before surgery can be dangerous and increase the risk of postoperative complications, suggests an editorial in this week?s BMJ. Surgery, particularly major abdominal surgery, affects the rate at which stomach contents are emptied, so reducing... view more... (2000-09-19)

Stress-induced changes in brain circuitry linked to cocaine relapse
Stress-evoked changes in circuits that regulate serotonin in certain parts of the brain can precipitate a low mood and a relapse in cocaine-seeking, based on mouse studies published online this week in the Proceedings of the National Academy of Sciences.   view more (2009-10-30)

Morphine and topical anesthesia found effective in treating pain in newborn infants
Intravenous morphine used alone or with topical tetracaine effectively reduced levels of pain in preterm newborn infants undergoing central line insertion procedures, according to a study in the February 15 issue of JAMA.   view more (2006-02-15)

New guidelines for prescribing opioid pain drugs published
A prestigious panel of pain-management experts representing the American Pain Society (APS) www.ampainsoc.org and the American Academy of Pain Medicine (AAPM) has published the first comprehensive clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.   view more (2009-02-10)

Hepatitis C complicated by morphine withdrawal
Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication.   view more (2005-10-31)

The G allele of the mu-opioid receptor gene is linked to craving for alcohol
The study of genes and their influence on alcohol consumption can operate on many different levels. Some studies examine how genes may interact with the environment, some look specifically at family history of alcohol dependence, and some zero in on "pieces" of genes and their influence on drinking.   view more (2007-01-04)

A comprehensive review of addiction to prescription painkillers among patients and physicians
Chemical dependency and recovery in patients and physicians are closely examined in a series of articles and editorials in the July 2009 issue of Mayo Clinic Proceedings.   view more (2009-07-08)

Infant pain, adult repercussions
Scientists at Georgia State University have uncovered the mechanisms of how pain in infancy alters how the brain processes pain in adulthood.   view more (2009-09-28)

Thinking the pain away? Study shows the brain's painkillers may cause 'placebo effect'
Just thinking that a medicine will relieve pain is enough to prompt the brain to release its own natural painkillers, and soothe painful sensations, a new University of Michigan study finds.   view more (2005-08-24)

Electroacupuncture at PC6 may decrease frequency of transient lower esophageal sphincter relaxation
The First Hospital of Peking University, China-Research, has shown that electroacupuncture at PC6 may decrease the frequency of transient lower esophageal sphincter relaxation (TLESR), which is the main mechanism underlying gastroesophageal reflux disease (GERD).   view more (2007-10-11)

New target for Alzheimer's disease identified
Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.   view more (2008-05-07)

Rats Move Toward the Food but Do Not Eat
Scientists led a rat to the fatty food, but they couldn't make it eat. Using an animal model of binge eating, University of Missouri researchers discovered that deactivating the basolateral amygdala, a brain region involved in regulating emotion, specifically blocked consumption of a fatty diet. Surprisingly, it had no effect on the rat wanting... view more... (2009-09-09)

Researchers find genetic link between physical pain and social rejection
UCLA psychologists have determined for the first time that a gene linked with physical pain sensitivity is associated with social pain sensitivity as well.   view more (2009-08-18)

Studies find that 'broken heart syndrome' can result from opioid withdrawal, cocaine use
People who experience abrupt withdrawal from high-dose opioids or use cocaine increase their risk of cardiac event, according to two new studies published in the June issue of Mayo Clinic Proceedings.   view more (2006-06-22)
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