Opioid Current Events | Opioid News | 3
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Imiquimod, an immune response modifier, is dependent on the OGF-OGFr signaling pathway Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor (OGFr) axis for its action. view more (2008-07-28)
'Thirst for knowledge' may be opium craving Neuroscientists have proposed a simple explanation for the pleasure of grasping a new concept: The brain is getting its fix. view more (2006-06-21)
Morphine: a comfort measure for the dying or pain control for the living? Cancer patients are suffering unnecessarily because they wrongly believe that morphine and other opioids are only used as "comfort for the dying" and as a "last resort" rather than seeing them as legitimate pain killers that can improve their quality of life. view more (2007-12-11)
Nerve-block anesthesia can improve surgical recovery, even outcomes When planning for surgery, patients too often don't consider the kind of anesthesia they will receive. In fact, the choice of anesthesia can improve recovery, even outcomes. view more (2009-08-05)
Study shows high rates, rising costs of alcohol/drug disorders in hospitalized patients Fourteen percent of patients admitted to the hospital have alcohol/drug abuse and addiction (ADAA) disorders, costs for which have risen sharply in recent years, according to a study in the June issue of the Journal of Substance Abuse Treatment (JSAT). view more (2008-06-25)
Regulation of cell proliferation by the OGF-OGFr axis is dependent on nuclear localization signals Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of the Opioid Growth Factor (OGF, [Met5]-enkephalin), a clinically important antitumor agent, is dependent on nucleocytoplasmic translocation and reliant on the integrity of nuclear localization signals in the OGF receptor... view more... (2009-04-23)
Food cue-related brain activity linked to obesity? A unique pattern of gene expression observed in rats may be linked to a conditioned desire for food and excessive food intake, an article published today in BMC Biology suggests. view more (2007-04-27)
Psychological intervention reduces postembolization pain Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy. It is highly recommended as a complementary approach to pharmacological analgesia according to research published in the February 14, 2008 issue of the World Journal of Gastroenterology. view more (2008-03-13)
New study shows epidural during birth may negatively affect breastfeeding Epidurals given during labour and birth are associated with decreased rates of breastfeeding, both in the short and long term. view more (2006-12-11)
New Treatment Option For Heroin Addiction (pp 634, 662) An alternative drug therapy to methadone for the treatment of heroin addiction is proposed by Swedish authors of a study in this week's issue of THE LANCET. Methadone is an established treatment for heroin addiction-however it is usually only given to long-term addicts as there are concerns that it is addictive. Buprenorphine has been suggested... view more... (2003-02-19)
Fluoxetine: antidepressant and a possible new drug for the treatment of obesity The Department of Nutrition and Bromatology of the Faculty of Pharmacy of Gasteiz, University of the Basque Country, is studying the action mechanism of fluoxetine in genetically fattened rats (Zucker fa/fa). Due to fluoxetine, those rats eat 50 % less. Therefore, the bodies put on less weight and the size of different fat tissues is reduced.... view more... (2002-07-30)
DNA highly-promising predictor for successful treatment of alcoholics According to Dutch researcher Wendy Ooteman, the biological and genetic characteristics of alcoholics can predict which drugs will best suppress the desire to drink. view more (2006-10-05)
New information points to safer methadone use for treatment of pain and addiction New findings may significantly improve the safety of methadone, a drug widely used to treat cancer pain and addiction to heroin and other opioid drugs, according to researchers at Washington University School of Medicine in St. Louis and the University of Washington in Seattle. view more (2009-03-03)
Methadone and systematic follow-up: the best solution for managing chronic pain Approximately 30% of Canadians suffer daily from chronic pain. Patients may be affected differently depending on the intensity, but all chronic pain is debilitating and difficult to treat. view more (2007-09-13)
Should heroin be prescribed to addicts? In this week's BMJ experts debate whether heroin should be prescribed to addicts who are difficult to treat. view more (2008-01-11)
Gene variant predicts medication response in patients with alcohol dependence Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health's 2001-2004 COMBINE (Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence)... view more... (2008-02-11)
Sugar can be addictive, Princeton scientist says A Princeton University scientist will present new evidence today demonstrating that sugar can be an addictive substance, wielding its power over the brains of lab animals in a manner similar to many drugs of abuse. view more (2008-12-10)
Data demonstrates alcohol does not significantly affect pharmacokinetics of Kadian Alpharma Inc. (NYSE: ALO), a leading global specialty pharmaceutical company, presented results of a Phase IV study of KADIAN® (morphine sulfate extended-release) Capsules that demonstrate the pharmacokinetics of the long-acting opioid are not significantly affected by the consumption of alcohol. view more (2007-02-12)
Free will takes flight: how our brains respond to an approaching menace Wellcome Trust scientists have identified for the first time how our brain's response changes the closer a threat gets. Using a "Pac Man"-like computer game where a volunteer is pursued by an artificial predator, the researchers showed that the fear response moves from the strategic areas of the brain towards more reactive responses as... view more... (2007-08-24)
Instanyl sets new standard in management of breakthrough cancer pain New data presented today further demonstrate the efficacy of Instanyl in management of breakthrough cancer pain. The data which were presented at the 6th congress of the European Federation of Chapters of the International Association for the Study of Pain (EFIC) are from a multinational, crossover trial comparing Instanyl with oral transmucosal... view more... (2009-09-11)
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