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Opioid Receptor Current Events | Opioid Receptor News

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Study advances evidence for receptor's role in alcohol pleasure and problems
A genetic variant of a receptor in the brain's reward circuitry heightens the stimulating effects of early exposures to alcohol and increases alcohol consumption, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National... view more (2007-03-07)

Prescription opioids the predominant choice among illicit opioid users
For almost a century, heroin addiction has been a core element of the illicit drug use problem in Canada. Recently, however, isolated reports have pointed to substantial increases in prescription opioid abuse.   view more (2006-11-21)

Potential new pain killer drug developed by scientists at Leicester and Italy
A potential new pain-killing drug developed by medical scientists at the University of Leicester and Ferrara in Italy is to be discussed at a public lecture on 20th March.   view more (2007-03-16)

Why don't painkillers work for people with fibromyalgia?
People who have the common chronic pain condition fibromyalgia often report that they don't respond to the types of medication that relieve other people's pain.   view more (2007-09-28)

Opioids and cannabinoids influence mobility of spermatozoids
A PhD thesis from the University of the Basque Country has concluded that there are opioid and cannabinoid receptors in human sperm and that these influence the mobility of spermatozoid.   view more (2008-06-23)

Large family study pinpoints genetic linkage in drug addiction
Based on data obtained from one of the largest family sets of its kind, Yale School of Medicine researchers have identified a genetic linkage for dependence on drugs such as heroin, morphine and oxycontin.   view more (2006-04-11)

Depression diversity: Brain studies reveal big differences among individuals
Depressed people may have far fewer of the receptors for some of the brain's "feel good" stress-response chemicals than non-depressed people, new University of Michigan Depression Center research shows.   view more (2008-05-08)

How does the opioid system control pain, reward and addictive behavior?
The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).   view more (2007-10-15)

Study examines use of opioids
Researchers from Boston University's Slone Epidemiology Center have found that in a given week, over 10 million Americans are taking opioids, and more than 4 million are taking them regularly (at least five days per week, for at least four weeks). These findings appear in the August 31 issue of the... view more (2008-08-28)

Long-term narcotics use for back pain may be ineffective and lead to abuse
Narcotic drugs (opioids) are commonly prescribed for short-term relief of chronic back pain, but their effectiveness long-term has been questioned in a review article by researchers at Yale School of Medicine, who also found that behaviors consistent with opioid abuse was reported in 24 percent of... view more (2007-01-18)

The G allele of the mu-opioid receptor gene is linked to craving for alcohol
The study of genes and their influence on alcohol consumption can operate on many different levels. Some studies examine how genes may interact with the environment, some look specifically at family history of alcohol dependence, and some zero in on "pieces" of genes and their influence... view more (2007-01-04)

OPICAN study in 7 Canadian cities reveals prescription opioid abuse more prevalent than heroin
A new study conducted in seven Canadian cities reveals that prescription opioids, and not heroin, are the major form of illicit opioid use. These findings raise questions about the current focus of Canada's drug control policy and treatment programs.   view more (2006-11-21)

INCREASED OPIOID USE AT END OF LIFE DOES NOT SHORTEN SURVIVAL (p 398)
Patients who receive increased doses of opioid at the end of their lives do not have shorter survival than those who receive no increases, concludes a research letter published in this week's issue of THE LANCET. Public and professional concern that the use of opioids for symptom control might... view more (2000-07-26)

Use of opioids for pain in ERs on the rise, but racial differences in use still exist
In the last 15 years, use of opioid medications to treat patients with pain-related emergency department visits has improved although white patients were more likely to receive opioids than patients of a different race/ethnicity, according to a study in the January 2 issue of JAMA.   view more (2008-01-02)

Pain patients at risk for sleep apnea
Opioid-based pain medications may cause sleep apnea, according to an article in the September issue of Pain Medicine, the journal of the American Academy of Pain Medicine.   view more (2007-09-07)

Study does not support use of anesthesia as heroin withdrawal method
The use of general anesthesia for heroin detoxification offers no benefit when compared to two other methods, and is associated with several potentially life-threatening adverse events.   view more (2005-08-24)

Morphine kills pain — not patients
Many people, including health care workers, believe that morphine is a lethal drug that causes death when used to control pain for a patient who is dying. That is a misconception according to new research published in the latest issue of Palliative Medicine, from SAGE Publications.   view more (2007-03-22)

Imiquimod, an immune response modifier, is dependent on the OGF-OGFr signaling pathway
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor... view more (2008-07-28)

Extended-treatment with combination medication for opioid-addicted youths shows benefit
Adolescents addicted to opioids who received continuing treatment with the combination medication buprenorphine-naloxone had lower rates of testing positive or reporting use of opioids compared to youths who went through a short-term detoxification program using the same medication, according to a... view more (2008-11-05)

Transporter is possible target for safer pain medicine
A transporter that silences one of the body's natural pain killers holds promise for new powerful, non-addictive pain medicines as well as understanding AIDS patients' increased pain perception.   view more (2006-06-12)

Antipsychotic drug may block addiction, UIC researchers find
Researchers at the University of Illinois at Chicago have discovered that a long-approved oral antipsychotic drug can stop the addictive properties of opioid painkillers in mice.   view more (2006-02-09)

Antibodies can halve risk of transplant rejection
Giving interleukin-2 receptor antibodies to patients after a kidney transplant can halve the risk of rejection, concludes a study in this week's BMJ. Researchers in Birmingham reviewed eight trials of interleukin-2 receptor antibodies versus placebo in 1,858 patients receiving standard... view more (2003-04-10)

DNA highly-promising predictor for successful treatment of alcoholics
According to Dutch researcher Wendy Ooteman, the biological and genetic characteristics of alcoholics can predict which drugs will best suppress the desire to drink.    view more (2006-10-05)

'Runner's high' may also strengthen hearts
Endorphins and other morphine-like substances known as opioids, which are released during exercise, don't just make you feel good -- they may also protect you from heart attacks, according to University of Iowa researchers.   view more (2007-11-09)

Inhaled asthma drugs more effective than oral therapy
Inhaled glucocorticoid drugs are more effective than the newer anti-leukotriene tablets for adults with mild or moderate asthma, concludes a study in this week’s BMJ.   view more (2003-03-19)
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