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Sleeping sickness parasite shows how cells divide their insides
Graham Warren, professor of cell biology, and his colleagues at Yale study Trypanosoma brucei, the parasite that causes Sleeping Sickness. view more (2005-11-08)
Commencement 2008: Undergrad Has Sweet Success With Invention of Artificial Golgi
An undergraduate student at Rensselaer Polytechnic Institute has learned very quickly that a spoonful of sugar really does help the medicine go down. In fact, with his invention, the sugar may actually be the medicine. view more (2008-05-08)
Features of replication suggest viruses have common themes, vulnerabilities
A study of the reproductive apparatus of a model virus is bolstering the idea that broad classes of viruses - including those that cause important human diseases such as AIDS, SARS and hepatitis C - have features in common that could eventually make them vulnerable to broad-spectrum antiviral... view more (2007-08-14)
Proteomics Study Yields Clues As To How Tuberculosis Might Be Thwarting The Immune System
A link between the immune system and the self-cleaning system by which biological cells rid themselves of obsolete or toxic parts may one day yield new weapons in the fight against tuberculosis and other deadly infectious diseases. view more (2008-11-06)
Protein found to shield pancreatic cancer cells from self-destruction
An overexpressed protein protects human pancreatic cancer cells from being forced to devour themselves, removing one of the body's natural defenses against out-of-control cell growth. view more (2007-03-20)
Peas and beans get by with more than a little help from friends
The relationship between leguminous plants such as peas and beans and nitrogen-fixing bacteria is even closer than previously thought, with bacteria acting like an intrinsic part of the plant, according to research published in the journal Nature today. Researchers from the University of Reading... view more (2003-04-14)
Proteasome activator enhances survival of Huntington's disease neuronal model cells
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. view more (2007-02-28)
Legionnaire's bacterial proteins work together to survive
Proteins within the bacteria that cause Legionnaire's disease can kidnap their own molecular "coffin" and carry it to a safe place within the cell, ensuring their survival, Yale School of Medicine researchers report in Nature Wednesday. view more (2007-10-24)
Sea Coral's Trick Helps Scientists Tag Proteins
The glow emitted by a variety of sea coral helped Russian scientists harness the protein that generates the light to create a tiny fluorescent tag that responds to visible light. view more (2006-03-20)
Why does an anti-anthrax drug kill plants too?
Scientists at the John Innes Centre (JIC), Norwich (1) have today reported that a very successful antibiotic, which is harmless to humans but lethal to most bacteria, also kills plants. They have found that an enzyme, which is an important target for several families of antibiotics and was thought... view more (2004-05-12)
Unfolded proteins may protect cells from dying
When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually serves a protective role; rather than a sign that the cell has given up, it may be a... view more (2006-12-27)
Decoded gene sequence of the diatom Thalassiosira pseudonana
For the very first time, the genetic make-up of a planktonic marine alga has been sequenced. During this process, a team of international scientists found unexpected metabolic pathways in the diatom Thalassiosira pseudonana. The results will be published in the scientific journal 'Science' this... view more (2004-10-01)
Sidestepping cancer's chaperone
Cancerous tumors are wildly unfavorable environments. Struggling for oxygen and nutrients while being bombarded by the body's defense systems, tumor cells in fact require sophisticated adaptations to survive and grow. view more (2007-10-22)
UVA studies potential target for skin cancer treatment
When normal skin cells become a melanoma tumor, they sometimes turn on genes not usually found in the skin. view more (2006-10-04)
Zeroing in on progeria: How mutant lamins cause premature aging
Children diagnosed with Hutchinson-Gilford Progeria Syndrome (HGPS) race through life against an unfairly fast clock. Cases are extremely rare-one in 8 million births-but time plays cruel tricks on HGPS newborns. view more (2005-12-14)
Discovery of metabolic pathway for parasite could lead to new controls for diseases
Toxoplasma gondii is one nasty bug. A microscopic parasite, it lives in the intestinal tract of cats but can be carried by most warm-blooded animals. In humans, it can harm or even kill a developing fetus, and it can as well sicken those with compromised immune systems, such as AIDS patients. view more (2006-08-15)
New understanding of parasite cell structures may provide treatments for serious tropical diseases
Don't even think about trying to pronounce it. Although it is found in many organisms including humans, glycosylphosphatidylinositol has remained a mouthful for laymen and a puzzle for scientists. view more (2006-05-10)
UA researchers find smallest cellular genome
The smallest collection of genes ever found for a cellular organism comes from tiny symbiotic bacteria that live inside special cells inside a small insect. view more (2006-10-13)
Regulating the Nuclear Architecture of the Cell
An organelle called the nucleolus resides deep within the cell nucleus and performs one of the cell's most critical functions: it manufactures ribosomes, the molecular machines that convert the genetic information carried by messenger RNA into proteins that do the work of life. view more (2006-12-11)
UF botanists: Flowering plants evolved very quickly into 5 groups
University of Florida and University of Texas at Austin scientists have shed light on what Charles Darwin called the "abominable mystery" of early plant evolution. view more (2007-11-27)
Mutations in the insulin gene can cause neonatal diabetes
Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections. view more (2007-09-11)
How the Neuron Sprouts Its Branches
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors. view more (2005-12-12)
New protein vital for immune response is found
A newly discovered protein not only is vital to the immune system's ability to fight off viral infections but also has been found in an unexpected location within the cell, causing researchers to rethink previous notions about the workings of the human immune system. view more (2005-08-26)
Pretreating rogue cancer cells with aspirin cripples their resistance to targeted therapy
For years, we have heard about the health benefits of taking low doses of aspirin - preventing everything from Alzheimer's disease to heart attacks and stroke. view more (2005-12-13)
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