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Down to the Bone
Although modern medical technology is already well advanced, implants made of synthetic materials can cause problems: they may give rise to rejection reactions or loosen over time because the contact between the surrounding tissue and the implanted material is not good enough. A remarkable... view more (1999-02-09)

Researchers reveal how long-term use of anti-inflammatory medication can cause osteoporosis
The steroid hormones glucocorticoids (GCs) are used at high doses to treat inflammatory and immune disorders, however they prompt bone loss and can cause osteoporosis, particularly when administered for prolonged periods.   view more (2006-07-28)

'Best of both worlds' — Targeting a single gene could inhibit bone decay and stimulate bone growth
Researchers at the University of Pennsylvania's School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation.   view more (2006-12-11)

Same process discovered to both form skeleton and protect it for life
A protein signaling pathway recently discovered to guide the formation of the skeleton in the fetus also keeps bones strong through adult life, according to two papers published recently in the journal Nature Medicine.   view more (2008-03-13)

Bone-Growing Nanomaterial Could Improve Orthopaedic Implants
For orthopaedic implants to be successful, bone must meld to the metal that these artificial hips, knees and shoulders are made of. A team of Brown University engineers, led by Thomas Webster, has discovered a new material that could significantly increase this success rate.   view more (2007-09-18)

Notch controls bone formation and strength
Notch, a protein known to govern the determination of cell differentiation into different kinds of tissues in embryos, plays a critical role in bone formation and strength later in life, said researchers from Baylor College of Medicine in Houston in a report that appears online today in the journal... view more (2008-02-25)

Building stronger bones, 1 stem cell at a time
Mesenchymal stem cells (MSCs) are bone marrow-derived cells that are capable of giving rise to various cell types through a process known as differentiation.   view more (2008-01-25)

Researchers discover how rheumatoid arthritis causes bone loss
Researchers have discovered key details of how rheumatoid arthritis (RA) destroys bone, according to a study published in the Aug. 22 edition of the Journal of Biological Chemistry.   view more (2008-08-21)

Researchers discover protein that controls bone growth
A research team led by Dr. Pierre Moffatt of the Shriners Hospital for Children in Montreal and McGill University's Department of Human Genetics has uncovered the molecular mechanism by which the protein osteocrin controls bone growth - a discovery that may have important implications for people... view more (2007-12-20)

Novel model of osteosarcoma
In the June 15th issue of G&D, Dr. Stuart Orkin (HHMI, Dana-Farber Cancer Institute, Children's Hospital Boston) and colleagues present a new mouse model of osteosarcoma.   view more (2008-06-16)

Research identifies protein in mice that regulates bone formation
Osteoporosis, a disease characterized by a decrease in bone mass and density and which makes people more susceptible to bone fractures and deformities, afflicts some 10 million Americans over the age of 50.   view more (2006-06-23)

Finding the right mix: A biomaterial blend library
From dental implants to hip replacements, biomaterials have become big business. But scientists pursuing this modern medical revolution share a basic challenge: biocompatibility.   view more (2006-10-30)

SUCCESS 2002 Student Contest award ceremony
Today, at the European Astronaut Centre in Cologne, the outcome of the SUCCESS 2002 Student Contest was announced to contestants eagerly waiting to see if their proposed experiment had won a prize in this competition organised every two years by the European Space Agency (ESA). The SUCCESS... view more (2003-08-29)

New 3-D test method for biomaterials 'flat out' faster
A novel, three-dimensional (3-D) screening method for analyzing interactions between cells and new biomaterials could cut initial search times by more than half, researchers from the National Institute of Standards and Technology (NIST) and Rutgers University report in the new issue of Advanced... view more (2008-04-30)

Study identifies molecule essential for proper localization of blood stem cells
Scientists at the Massachusetts General Hospital (MGH) Center for Regenerative Medicine and the Harvard Stem Cell Institute (HCSI) have defined a molecule that dictates how blood stem cells travel to the bone marrow and establish blood and immune cell production.   view more (2006-01-16)

Connection between depression and osteoporosis shown by Hebrew University researchers
Depression can cause a loss of bone mass, leading to osteoporosis and fractures, say researchers at the Hebrew University of Jerusalem.   view more (2006-10-31)

Commonly prescribed antidepressants associated with lower bone density in older men and women
The class of antidepressant medications known as selective serotonin reuptake inhibitors may be associated with an increased rate of bone loss in older men and women.   view more (2007-06-26)

Research shows skeleton to be endocrine organ
Bones are typically thought of as calcified, inert structures, but researchers at Columbia University Medical Center have now identified a surprising and critically important novel function of the skeleton.   view more (2007-08-10)

Leukemic cells find safe haven in bone marrow
The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to investigators at St. Jude Children's Research Hospital.   view more (2007-03-23)

Bones hold the key to blood renewal
Though we think of them as solid and permanent, our bones are actually constantly being rebuilt throughout our lives. A team of scientists at the Weizmann Institute of Science has now revealed how cells that work at remodeling the bones play a direct part in the ongoing renewal of another system... view more (2006-06-20)

Small protein may have big role in making more bone and less fat
A small protein may have a big role in helping you make more bone and less fat, researchers say.   view more (2008-07-02)

New weapon in battle against osteoporosis
Medical researchers at the University of Bonn, working in collaboration with scientists from Israel, the USA and Britain, have identified a previously unknown regulatory mechanism in the process of bone loss. Their findings could open up new approaches to the treatment of osteoporosis.   view more (2006-01-03)

Plant-derived omega-3s may aid in bone health
Plant-based omega-3 polyunsaturated fatty acids (PUFA) may have a protective effect on bone health, according to a team of Penn State researchers who carried out the first controlled diet study of these fatty acids contained in such foods as flaxseed and walnuts.   view more (2007-02-20)
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