Pancreatic Current Events | Pancreatic News | 7
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Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?
Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate. view more (2008-12-29)
Arterial infusion using gabexate mesilate: Is it effective therapy for severe acute pancreatitis?
Severe acute pancreatitis (SAP) remains a lethal disease. It is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi-organ involvement inducing multi-organ dysfunction syndrome (MODS) with an increased mortality rate. view more (2008-12-30)
Mouse model developed at UT Southwestern mimics hyperglycemia, aids in diabetes research
UT Southwestern Medical Center researchers have genetically engineered a laboratory mouse in which pancreatic beta cells can regenerate after being induced to die. The new animal model's regenerative ability may provide future insights into improved treatments of diabetes, which affects millions of Americans. view more (2008-06-02)
Method shows promise for early detection of pancreatic cancer
Optical technology developed by a Northwestern University biomedical engineer shown to be effective in the early detection of colon cancer now appears promising for detecting pancreatic cancer, the fourth most common cause of cancer deaths in the United States. view more (2007-08-01)
Popular diabetes treatment could trigger pancreatitis, pancreatic cancer
A drug widely used to treat Type 2 diabetes may have unintended effects on the pancreas that could lead to a form of low-grade pancreatitis in some patients and a greater risk of pancreatic cancer in long-term users, UCLA researchers have found. view more (2009-05-01)
Pioneering surgical technique in Spain enables extirpation of benign tumours of the pancreas - preserving the organ's function to the maximum
A laparoscopic surgical technique enables extirpation of pancreatic tumours that are benign or of scant, highly localised malignant potential and that preserves the function of the organ to the maximum, at the same time significantly reducing the number of possible complications and the period of hospitalisation. view more (2009-02-04)
New study reveals signaling pathways required for expansion of pancreas stem cells
IDDM, which used to be referred to as Type 1 diabetes, results from selective destruction of insulin-producing pancreatic islet beta cells by the body's immune system. view more (2006-05-17)
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys - all without the need for risky immune suppression drugs that prevent rejection. view more (2007-10-19)
Dynamic duo: Combination therapy reverses type 1 diabetes
Researchers have now carefully crafted a combination therapy that reverses recent-onset type 1 diabetes in 2 animal models of disease. view more (2006-04-21)
Short-term hemofiltration is cost-effective for severe acute pancreatitis
Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis. From meta-analysis based on current available clinical studies early nasogastric enteral nutrition appeared effective and safe in clinical practice. view more (2007-10-15)
Gene therapy eradicates pancreatic cancer in preclinical trial
A molecularly engineered therapy selectively embeds a gene in pancreatic cancer that shrinks or eradicates tumors, inhibits metastasis, and prolongs survival with virtually no toxicity. view more (2007-07-10)
Mounting evidence shows red wine antioxidant kills cancer
Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function. The study is published in the March edition of the journal, Advances in Experimental Medicine and Biology. view more (2008-03-26)
Researchers identify a role for glucose-sensing neurons in type 2 diabetes
In cases of Type 2 diabetes, the body's cells fail to appropriately regulate blood glucose levels. Research has suggested that this results from two simultaneous problems: the improper functioning of pancreatic beta cells and the impairment of insulin's actions on target tissues, including the liver, fat and muscles. view more (2007-08-30)
Optical techniques show continued promise in detecting pancreatic cancer
Optical technology developed by a Northwestern University professor of biomedical engineering has been shown to be effective in detecting the presence of pancreatic cancer through analysis of neighboring tissue in the duodenum, according to clinical trial results published in the journal Disease Markers. view more (2009-03-03)
Imaging features of intraductal papillary mucinous neoplasms of the pancreas
The intraductal papillary mucinous neoplasms (IPMN) can evolve through all biological stages, from slight dysplasia to carcinoma. view more (2009-09-16)
Researchers pit novel version of common virus against cancer
With nearly $1 million in government funding, University of Rochester scientists are testing a new innovation in biotherapy by altering a common childhood respiratory virus, the adenovirus, to destroy cancer cells. view more (2007-06-21)
Enzyme defect leads to hyperinsulinism
A recent study in the Journal of Biological Chemistry confirms that mutations in an enzyme called glutamate dehydrogenase can cause congenital hyperinsulinism. view more (2006-05-25)
Minimally invasive pancreas surgery leads to fewer complications, study finds
When surgeons need to remove part of the pancreas, performing the operation with minimally invasive techniques offers patients a shorter hospital stay and fewer complications, researchers have concluded. view more (2008-04-25)
Vitamin C injections slow tumor growth in mice
High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences. view more (2008-08-05)
Gardenia fruit compound starting point for diabetes therapy
A Gardenia fruit extract traditionally used in Chinese medicine to treat the symptoms of type 2 diabetes does indeed contain a chemical that reverses some of the pancreatic dysfunctions that underlie the disease. view more (2006-06-07)
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