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Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell... view more (2007-08-01)

OHSU researcher develops first animal model to treat devasting head and neck cancers
An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.   view more (2006-05-16)

High circulating D-dimers are associated with presence of ascites
The liver is the production site of most of the proteins which favour and inhibit the process of coagulation and fibrinolysis.   view more (2008-04-30)

Radiation dose reduction in liver cancer
A new digital angiography flat panel system reduces the radiation dose to patients undergoing interventional treatment for liver cancer by about one-fourth, a new study shows.   view more (2005-10-03)

Massive necrosis after trans-catheter treatment is more common in the presence of tumor capsule
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Prognosis of patients with HCC complicating cirrhosis mainly depends on the tumor growth, progression of the underlying liver disease and the effectiveness of antitumoral treatment.   view more (2007-11-26)

Imiquimod, an immune response modifier, is dependent on the OGF-OGFr signaling pathway
Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the efficacy of imiquimod, a clinically important immune response modifier with potent antiviral and antitumor activity, is dependent on the Opioid Growth Factor (OGF)-OGF receptor... view more (2008-07-28)

Candidate markers for gastric cancer
The sequencing of the human genome has opened the door for proteomics by providing a sequence-based framework for mining proteomes.   view more (2008-10-29)

Keyhole Surgery For Colorectal Cancer Offers Same Prognosis As Conventional Surgery (p 1187)
Laparoscopy ('keyhole surgery') for colorectal cancer could be the future treatment of choice after results of a study from Hong Kong in this week's issue of THE LANCET show how it is associated with a similar 5-year survival outcome and more favourable recovery time than conventional surgery.... view more (2004-04-07)

CHEMOEMBOLISATION OFFERS SURVIVAL BENEFIT FOR PEOPLE WITH LIVER CANCER (p 1734)
People with liver cancer that cannot be treated with surgical resection or transplantation could have an increased two-year survival if they are given chemoembolisation-a procedure in which blood supply to the tumour combined with the effect of chemotherapy inhibits cancer growth. There is no... view more (2002-05-15)

'Treatment disconnect' in kidney cancer: Rising mortality despite more small tumors, more surgery
The rising incidence of kidney cancer may be due to an increase in the number of small, treatable kidney tumors.   view more (2006-09-20)

A new insight on ethanol-induced gastric mucosa injury
Many people all over the world indulge themselves in drinking, which is correlated to a wide spectrum of medical, psychological, behavioral, and social problems.   view more (2008-10-24)

No Benefits From Vitamin Supplements In Protection Against Gastro-Intestinal Cancer (pp 1193, 1219)
A systematic review and meta-analysis (pooled analysis) of previously published randomised trials in this week's issue of THE LANCET provides strong evidence that antioxidant supplements (such as vitamin supplements) are not effective in protecting against gastro-intestinal cancer. Some... view more (2004-09-29)

HtrA1 and resistance to chemotherapy in ovarian and gastric cancers
While many cancer patients initially have a favorable response to chemotherapy for the treatment of solid tumors, resistance to treatment often develops.   view more (2006-06-09)

Radiofrequency ablation highly effective in treating kidney tumors
A relatively new, minimally invasive treatment was 93 percent successful in eradicating malignant kidney tumors, according to a recent study conducted by researchers from Wake Forest University Baptist Medical Center in Winston-Salem, NC.   view more (2007-08-06)

UT Southwestern doctors test robotic surgeon for laparoscopy
Having a surgeon with four arms is one of the advantages of the latest robotic technology now being studied at UT Southwestern Medical Center.   view more (2006-02-15)

Gastric juice for diagnosis of H. pylori infection in patients on proton pump inhibitors
This study determined the efficiency of a gastric juice PCR test for the detection of H. pylori infection in patients receiving PPI therapy and compared it with histology and gastric biopsy PCR.   view more (2008-04-30)

Skin cancer rare - but more deadly - in people with darker skin
New research from the University of Cincinnati (UC) shows that dark-skinned people-commonly thought to be "immune" to most skin cancers-are more likely than whites to die from skin cancer and its related complications.   view more (2006-07-28)

Molecular studies in cancer of the colon
According to Dr. Jes√∫s Garc√≠a-Foncillas, Director of the Department of Oncology at the University Hospital (University of Navarra), molecular studies in cancer of the colon will contribute to the establishment of more efficient and less toxic treatments.   view more (2005-10-24)

Age, burden, divorce and heavy tea consumption are significant risk factors for erosive esophagitis
Gastroesophageal reflux disease (GERD) is a common disorder with a high incidence rate in adults of 10 - 38%. The diagnosis and treatment of GERD are therefore important because the disease, in addition to the highly disturbing typical symptoms, has a series of known consequences.   view more (2007-11-26)

High risk of breast cancer associated with genetic variation in leptin and its receptor
Individuals with either of two genetic variations that lead to high serum levels of the cytokine leptin and to overexpression of leptin in fatty tissue, are more at risk of developing breast cancer than others.   view more (2006-02-21)

Molecular imaging technology used in gastric cancer
Modern cancer care is critically dependent on imaging technologies, which are used to detect early tumors and guide their therapy or surgery. Molecular imaging technologies provide information about the functional or metabolic characteristics of malignancies, tumor stage and therapeutical response,... view more (2008-09-25)

MRI spots DCIS in mice
A new magnetic resonance imaging procedure can detect very early breast cancer in mice, including ductal carcinoma in situ (DCIS), a precursor to invasive cancer. Some of the tumors detected were less than 300 microns in diameter, the smallest cancers ever detected by MRI.   view more (2008-10-01)

Percutaneous radiofrequency ablation of liver tumors prove safe and effective
Percutaneous imaging guided radiofrequency ablation (RFA) of hepatocellular carcinoma is a safe and effective technique, with benefits such as reduced post-procedural pain and length of hospital stay.   view more (2007-05-07)

Study shows positive findings in treating patients with advanced hepatitis C
The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented... view more (2008-04-25)

Helicobacter pylori Acquisition Most Common In Young Children (P931)
A US study in this week's issue of THE LANCET highlights how most newly acquired infections of the intestinal bacterium Helicobacter pylori probably occur in children younger than 10 years of age. The authors of the study suggest that treatment and prevention strategies should therefore be targeted... view more (2002-03-13)
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