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Genetic analysis predicts whether liver cancer likely to recur
Researchers are poised to unlock the genetic secrets stored in hundreds of thousands of cancer biopsy samples locked in long-term storage and previously thought to be useless for modern genetic research.   view more (2008-10-16)

Mayo Clinic's new imaging technology accurately identifies a broad spectrum of liver disease
A new study shows that an imaging technology developed by Mayo Clinic researchers can identify liver fibrosis with high accuracy and help eliminate the need for liver biopsies. Liver fibrosis is a common condition that can lead to incurable cirrhosis if not treated in time.   view more (2008-11-03)

A strange case of upper obstructive syndrome
Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI).   view more (2008-02-25)

New smear test policy puts young women at risk, say doctors
Last month, the BMJ reported a fall in the number of young women attending smear tests. Now, two senior doctors warn that a new policy not to screen women aged 20-24 may be a factor in falling coverage and could increase the risk of cancer developing in young women.   view more (2007-02-09)

History of nonmelanoma skin cancer is associated with increased risk for subsequent malignancies
Individuals with a history of nonmelanoma skin cancer (NMSC) are at increased risk for other cancers, according to a study published in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

CASE STUDY HIGHLIGHTS IMPORTANCE OF EARLY DETECTION OF TESTICULAR CANCER (pp 1632, 1666)
A case study in this week's issue of THE LANCET highlights how young men put their lives at risk by hiding large testicular lumps. HD de Boer and colleagues from UMC St Radboud, Nijmegen, Netherlands, describe a case in which a young man was in a motor-vehicle accident. He was examined by his... view more (2002-05-08)

Gemcitabine and capecitabine improved overall survival in patients with advanced pancreatic cancer
The prognosis of pancreatic cancer is poor but new therapies such as gemcitabine have contributed to improving the outcome for patients.   view more (2005-11-03)

Vaccination with embryonic stem cells prevents lung cancer in mice
Researchers in America have discovered that vaccinating mice with embryonic stem cells prevented lung cancer in those animals that had had cancer cells transplanted into them after the vaccination or that had been exposed to cancer-causing chemicals.   view more (2006-11-08)

Which is more accurate on diagnosis of rectal carcinoma?
The depth of transmural tumor invasion along the rectal wall layers and involvement of the regional lymph nodes constitute major factors in the prognosis of rectal cancer.   view more (2008-09-25)

Radiotherapy Best Option After Surgery For Ductal Carcinoma In Situ (p 95)
UK research published in this week's issue of THE LANCET suggests that women with a pre-invasive cancer of the breast known as ductal carcinoma in situ (DCIS) are less likely to progress to invasive cancer if they are given radiotherapy after surgery. Mammographic breast screening (introduced in... view more (2003-07-09)

Doubling of deaths from alcoholic liver disease - drug abuse during 1970s and 1980s may explain why
Middle-aged men could be at increased risk of death from liver disease, as a result of illicit intravenous drug use during the 1970s and 1980s, according to a study published today.   view more (2002-07-31)

Screening mammography in elderly patients beneficial
Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner.   view more (2008-04-14)

CT colonography even safer than previously reported, says study
The safety profile for CT colonography (CTC) is extremely favorable, particularly for the purposes of screening patients with no symptoms and when distending the colon using an automated carbon dioxide technique, a finding that goes against the higher complication rates for CTC reported by other... view more (2006-05-02)

Targeting nerve growth factor may cure liver cancer
Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the nervous system including brain.   view more (2007-09-19)

How to treat gastroesophageal adenocarcinom patients?
Gastroesophageal adenocarcinomas have a poor prognosis. However, numerous randomized clinical trials (RCT) have evaluated, and continue to evaluate, the survival benefit of various treatment regimens.   view more (2008-09-18)

Nanoparticles + light = dead tumor cells
Medical physicists at the University of Virginia have created a novel way to kill tumor cells using nanoparticles and light.   view more (2008-07-30)

CHANGING TRENDS OF UK CERVICAL CANCER SUGGESTS POSITIVE EFFECT OF SCREENING ON SPECIFIC SUBTYPE (p 1490)
Recent cervical cancer data compared with data from previous decades suggest that cervical screening is having a positive effect in reducing incidence of a subtype of the disease that was not previously thought to be influenced by screening, conclude authors of a study in this week's issue of THE... view more (2001-05-09)

Feedback loop found that could forestall liver disease
Researchers at UT Southwestern Medical Center have discovered that the small intestine communicates with the liver to control the production of bile acids-a finding that has great medical implications in treating people at risk for certain types of liver disease.   view more (2005-10-12)

H. Pylori bacteria may help prevent some esophageal cancers
Some bacteria may help protect against the development of a type of esophageal cancer, known as adenocarcinoma, according to a new review of the medical literature. These bacteria, which are called Helicobacter pylori, live in the stomachs of humans.    view more (2008-10-06)

Protein holds back growth of head and neck tumors
A protein associated with the growth of head and neck tumors may be a tumor suppressor that could prevent the spread of cancer when it is expressed above normal levels.   view more (2006-02-01)

Some benign breast lesions could be dangerous
Certain breast lesions diagnosed as benign on core needle biopsy have cancer at surgical excision and thus should be removed, according to a study appearing in the March issue of Radiology.   view more (2006-02-28)

Endocrine Society releases guideline on diagnosis and treatment of primary aldosteronism
The Endocrine Society has released a new clinical practice guideline for the detection, diagnosis, and treatment of patients with primary aldosteronism. The guidelines appear in the September issue of the Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of The Endocrine... view more (2008-08-28)

Study examines genetic factors associated with head and neck cancer
Preliminary research indicates that several specific genetic alterations are associated with the development of smoking-related head and neck skin cancers.   view more (2007-01-10)

Stopping the clock: Genetics of tumor latency in skin cancer
Dr. Anthony E. Oro and colleagues (Stanford University) have identified two key Gli protein degradation signals that directly affect tumor latency in a mouse model of human skin cancer.   view more (2006-01-20)

The clue of genomic instability in breast cancer
New research has shown, using human tissue biopsies - a hypothesis that until now could only be argued indirectly using cell cultures - that the significant increase in genomic "disorder" that is associated with breast cancer occurs in the transition between the typical hyperplasia and the in situ... view more (2004-09-07)
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