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A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
Skin cancer is the most prevalent form of human cancer in the United States, according to the Centers for Disease Control.   view more (2007-09-05)

Targeted therapy shows significant benefits over standard treatment for advanced kidney cancer
According to a new study, the drug sunitinib malate (Sutent®) is more effective than the current standard cytokine treatment given as an initial therapy for patients with advanced kidney cancer, also known as metastatic renal cell carcinoma (mRCC).   view more (2006-06-05)

Study hints at role of stem cell genes in testicular, breast cancers
UCSF scientists have discovered that the activity of several embryonic stem cell genes is elevated in testicular and breast cancers, providing some of the first molecular evidence of a link between embryonic stem cells and cancer.   view more (2005-11-30)

Nexavar shown to significantly extend survival for patients with advanced liver cancer
Bayer Pharmaceuticals Corporation (NYSE: BAY) and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced that an independent data monitoring committee (DMC) has reviewed the safety and efficacy data from the companies' pivotal Phase 3 trial in patients with advanced hepatocellular carcinoma... view more (2007-02-13)

Long-term hormone replacement therapy increases breast cancer risk
"Are you taking or did you take hormones? If yes, which hormone medication and for how long? When did you stop taking hormone replacement medication?" 3,464 breast cancer patients and 6,657 healthy women between the ages of 50 and 74 years participated in a large survey and elicited... view more (2008-05-29)

Breast conservation a good option for non-invasive, 'early' breast cancer, U-M study shows
For women diagnosed with a type of non-invasive breast cancer, removing the breast is not the only treatment option.   view more (2006-05-08)

Women still face cancer risk 25 years after treatment
Women are still at risk of developing invasive cancer of the cervix or vagina 25 years after being treated for pre-cancerous lesions, according to a study published today on bmj.com.   view more (2007-10-26)

CSHL scientists trace causal link between a tumor suppressor gene and liver cancer
Scientists at Cold Spring Harbor Laboratory (CSHL) have taken the search for cancer-causing genes an important step forward. In a newly published paper, they confirm that a gene called DLC1 is a tumor suppressor. They have demonstrated in living mice that its deletion, inactivation or loss... view more (2008-06-04)

HIV-1-Positive Women At Increased Risk Of Genital Cancer
A study in this week's issue of THE LANCET suggests that women who are HIV-1 positive are at an increased risk of invasive genital cancer. Authors of the study recommend that gynaecological examination of these women should include examination of the vulva and perianal region to identify genital... view more (2002-01-11)

Faster radiotherapy more effective in head and neck cancer, trial shows
The world's largest trial in accelerated radiotherapy for head and neck cancer - the DAHANCA trial - proves conclusively that increasing the number of treatments per week from five to six can benefit patients.   view more (2003-09-15)

Study examines association between type of genetic characteristics and cancer
Persons with a certain type of homozygosity (having two identical copies of the same gene, one inherited from each parent), may have a greater predisposition to cancer, according to a study in the March 26 issue of JAMA.   view more (2008-03-26)

Study provides evidence supporting recommended 10 year interval for colonoscopies for most patients
Patients with a negative colonoscopy examination have a reduced risk of developing colorectal cancer for more than 10 years, compared to the general population.   view more (2006-05-24)

Journal of the National Cancer Institute
Women with a relatively rare and aggressive form of breast cancer tend to be younger, have larger tumors, and have a poorer survival rate compared with women with the most common forms of the disease, reports a new study in the July 6 issue of the Journal of the National Cancer Institute.   view more (2005-07-06)

Early detection of lung cancer
This study was aimed at the detection of lung cancer in its early stages amongst high-risk persons by means of Computerised Axial Tomography (CAT).   view more (2005-04-20)

A new way to look at lung cancer and tobacco carcinogens
Two types of cancer-causing agents in cigarettes-a nicotine-derived chemical and polycyclic aromatic hydrocarbons (PAHs) are the main culprits in lung cancer. Exposure to tobacco smoke - both mainstream and second-hand - is a leading cause of cancer death in the United States.   view more (2008-05-29)

Quintet of proteins forms new, early-warning blood test before heart attack strikes
A team of Johns Hopkins biochemists has identified a mixed bag of five key proteins out of thousands secreted into blood draining from the heart's blood vessels that may together or in certain quantities form the basis of a far more accurate early warning test than currently in use of impending... view more (2008-11-10)

Can liver cirrhosis be partially cured?
The diffusion of hepatitis C virus infection worldwide is astonishing. Liver cirrhosis is present in at least 10-20% of these infected patients, with highly increasing health care and emotional costs.   view more (2007-10-11)

Preliminary study shows promise for treatment of renal cell cancer
A new study suggests that sunitinib is a promising agent for treatment of metastatic renal cell cancer, currently a disease without highly effective treatment options.   view more (2006-06-07)

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered
Earlier this year, researchers at the University of Pennsylvania School of Medicine identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers.   view more (2005-12-27)

Candidate genes found which may play a role in cancer progressing from non-invasive to invasive
Scientists in America have made the first steps in identifying a group of genes which may be involved in the progression of breast cancer from non-invasive to invasive, the 3rd European Breast Cancer Conference in Barcelona heard today (Thursday 21 March).   view more (2002-03-19)

Synergistic growth inhibitory effect of herbal extracts against HCC and lung cancer cells
Several herbs with diversified pharmacological properties are known to be rich sources of chemical constituents that may have potential for the treatment of several human cancers. Data from the Department of Preclinical Science, Faculty of Medicine, Thammasat University, demonstrates that the... view more (2008-04-30)

Molecular 'marker' on stem cells aids research, perhaps therapies
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT... view more (2006-12-04)

OHSU finds association between Epstein-Barr virus, inflammatory diseases of the mouth
Researchers at Oregon Health & Science University's School of Dentistry (www.ohsu.edu/sod) have found that a significant percentage of dental patients with the inflammatory diseases irreversible pulpitis and apical periodontitis also have the Epstein-Barr virus.   view more (2008-11-11)

The Lancet Oncology
CLEAR SKIES NOT SO CLEAN This months Leading Edge editorial examines the recently published US Environmental Protection Agency`s (EPA) 10-year in-the-making report on the toxic effects of diesel exhaust fumes from large vehicles. The report-which showed that large cities are heavily polluted with... view more (2002-10-02)

Larynx preservation preferred over total laryngectomy
Patients with locally advanced laryngopharyngeal cancers who receive radical chemoradiation have significantly better voice outcomes during the 12 months following treatment when compared with patients who have undergone a total laryngectomy and surgical voice restoration.   view more (2008-02-04)
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