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Gene that helps mosquitoes fight off malaria parasite identified
Researchers have identified a gene in mosquitoes that helps the insects to fight off infection by the Plasmodium parasite, which causes malaria in humans. Anopheles mosquitoes transmit the malaria parasite to nearly 550 million people worldwide each year with these cases resulting in more than 2 million deaths annually.   view more (2005-10-25)

A Bacterial Genome Reveals Targets to Combat Disease: Press Release from PLoS Biology
A bacterial genome reveals new targets to combat infectious disease   view more (2005-03-22)

IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies.   view more (2006-06-16)

Eye-opening research provides important diagnostic tool for major childhood killer
The eye can provide a very reliable way of diagnosing cerebral malaria, researchers in Malawi have shown.   view more (2006-11-07)

Onchocerciasis treatment reduces prevalence and intensity by 38%
Onchocerciasis, river blindness or craw craw is an endemic disease in Bioko Island, Equatorial Guinea.   view more (2006-07-31)

Poor Americans in the United States suffer hidden burden of parasitic and other neglected diseases
Large numbers of the poorest Americans living in the United States are suffering from some of the same parasitic infections that affect the poor in Africa, Asia, and Latin America, says the Editor-in-Chief of PLoS Neglected Tropical Diseases.   view more (2007-12-26)

Older drugs may be good stopgap treatment for malaria in Africa
A combination of older malaria drugs could treat malaria efficiently in some parts of Africa until a newer antimalarial drug called is widely available in those areas, a new review of recent studies suggests.   view more (2006-01-25)

How Toxoplasma gondii gets noticed
Researchers provide insight into how Toxoplasma gondii, a common parasite of people and other animals, triggers an immune response in its host.   view more (2009-01-20)

Parasites that live inside cells use loophole to thwart immune system
St. Jude Children's Research Hospital scientists have discovered a mechanism by which intracellular pathogens can shut down one of the body's key chemical weapons against them: nitric oxide.   view more (2008-11-04)

Possible new compound for treatment of cerebral malaria
In a paper published online in PLoS Medicine researchers from Marseille describe the effects of a new compound that may be a future treatment for patients with cerebral malaria.   view more (2005-08-23)

Earlier bites by uninfected mosquitoes boost West Nile deaths in lab mice
There's one more reason to try to avoid being bitten by mosquitoes, scientists have discovered: bites from mosquitoes that aren't infected by the West Nile virus may make the disease worse in people who acquire it later from West Nile-infected mosquitoes.   view more (2007-11-16)

Case Western Reserve researchers discover the key to malaria susceptibility in children
A team of researchers from Case Western Reserve University School of Medicine have solved the mystery of why some children are more susceptible to malaria infection and anemia.   view more (2009-07-28)

Parasitic tropical diseases in the Americas, a legacy of slavery, can be eliminated
Although it has been speculated for more than a century that the slave trade was responsible for bringing many tropical diseases to the Americas, only recently has convincing evidence shown that lymphatic filariasis (elephantiasis), schistosomiasis, and onchocerciasis (river blindness) originated in this way.   view more (2007-11-07)

European Commission funded research leads to effective new malaria drug
In an article published in the latest issue of The Lancet 1) , an international consortium, funded by a EUR1.8 million research grant from the European Commission, reports successful efficacy trials of a new candidate drug against malaria. If these initial results are confirmed a new drug could be available within 3 years. This raises new hopes in... view more... (2002-12-13)

Discovery of method to combat toxic algal blooms and description of a new group of organisms
In the fall of 1997 a then unknown species of plankton, Parvilucifera infectans, was discovered in the Gullmar Fjord, on the west coast of Sweden. The organism is a parasite that infects and kills several species of toxic algae. Some of these toxic algae can generate extremely potent blooms at great cost to fisheries and the tourism industry... view more... (2002-04-18)

Researchers gain ground in efforts to fight parasite infection
New findings by researchers UT Southwestern Medical Center are accelerating efforts to eradicate worm infections that afflict a third of the world's population.   view more (2009-05-27)

Global warming not responsible for malaria increase in East African Highlands
Recent increases in malaria in the East African Highlands cannot be attributed to global warming, researchers at the Department of Zoology at Oxford University have shown. It has long been known that malaria in highland areas is hindered by low temperatures which limit the development of the parasites in the mosquito. Recent upsurges of malaria in... view more... (2002-02-21)

Evolution-proof insecticides may stall malaria forever
Killing just the older mosquitoes would be a more sustainable way of controlling malaria, according to entomologists who add that the approach may lead to evolution-proof insecticides that never become obsolete.   view more (2009-04-07)

Discovery of metabolic pathway for parasite could lead to new controls for diseases
Toxoplasma gondii is one nasty bug. A microscopic parasite, it lives in the intestinal tract of cats but can be carried by most warm-blooded animals. In humans, it can harm or even kill a developing fetus, and it can as well sicken those with compromised immune systems, such as AIDS patients.   view more (2006-08-15)

DIAGNOSTIC TEST SHOULD LEAD TO BETTER CONTROL
A genetic test targeted at cattle could have a substantial impact in controlling sleeping sickness in east Africa, conclude authors of a fast-track study in this week's issue of THE LANCET. Sleeping sickness caused by Trypanosoma brucei rhodesiense (transmitted by the tsetse fly) is fatal if not treated. Drug treatment can be associated with... view more... (2001-12-12)
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