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Scientists find the pathological prion protein in skeletal muscles of hamster with scrapie
In the May 2003 issue of EMBO reports, researchers from the German Robert Koch Institute in Berlin report finding the pathological prion protein PrPSc in a wide range of skeletal muscles after feeding hamsters with prion-infected food. PrPSc is believed to be an essential - if not the sole - constituent of the agent that causes BSE in cattle,... view more... (2003-04-10)

Compulsive gamblers always down on their luck
Gambling addicts don't learn from their mistakes, according to a study published today in the open access journal Clinical Practice and Epidemiology in Mental Health. The problem could be explained by a kind of mental rigidity that leads to harmful compulsive behaviour in sufferers.   view more (2008-03-27)

Gastric cancer with 3 pathological features
Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma.   view more (2008-09-18)

Liver cell adenoma or hepatocellular carcinoma?
Recently, LCAs with typical backgrounds of the patients are diagnosed by radiological findings without pathological findings due to the progress of diagnostic imaging techniques.   view more (2009-03-20)

Characteristic pathological findings in reflux esophagitis
Recently, the number of patients with GERD has increased in Japan. However, there have been few reports about the pathological findings in the esophageal squamous epithelium, and there are differing opinions among pathologists about the findings considered characteristic of chronic reflux esophagitis.   view more (2009-08-10)

Anti-wrinkle compound causes pathological reaction in skin cells
Researchers from Université Laval's Faculty of Medicine have discovered that a compound commonly used in many antiwrinkle products causes a pathological reaction in skin cells.   view more (2007-04-12)

Is 31P MRS a useful tool for evaluating early acute hepatic radiation injury?
Acute hepatic radiation injury could lead to necrosis of hepatocytes, fatty degeneration and hepatic fibrosis. At the present, the gold standard test is liver biopsy.   view more (2009-06-24)

U of M study: Health food supplement may curb addiction of pathological gamblers
University of Minnesota researchers have discovered that a common amino acid, available as a health food supplement, may help curb pathological gamblers' addiction.   view more (2007-09-12)

Novel mouse gene reduces major pathologies associated with Alzheimer's disease
A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD).   view more (2009-11-12)

Prison gambling associated with crime, substance abuse when offenders re-enter community: Study
Parolees with a gambling habit may resort to criminal activities and substance abuse when they are released from prison if there are few community supports to help them re-integrate, a University of Alberta study has concluded.   view more (2009-09-17)

Study finds no relationship between PCR rate and race in women with breast cancer
Locally advanced breast cancer patients who received the same class of neoadjuvant chemotherapy were found to have no evidence of disease at the time of their surgery, or achieved pathological complete response, at the same rate regardless of race, according to researchers at The University of Texas M. D. Anderson Cancer Center.   view more (2009-10-12)

New analysis shows 'hobbits' couldn't hustle
A detailed analysis of the feet of Homo floresiensis-the miniature hominins who lived on a remote island in eastern Indonesia until 18,000 years ago-may help settle a question hotly debated among paleontologists: how similar was this population to modern humans?   view more (2009-05-07)

Hold your horses
For those who suffer with the debilitating symptoms of Parkinson's disease, Deep Brain Stimulation offers relief from the tremors and rigidity that can't be controlled by medicine.   view more (2007-10-26)

A case of false positive octreoscan in Crohn's disease
Neuroendocrine tumors, such as carcinoid tumors, overexpress somatostatin receptors in their membranes. Octreotide is an analogue whose molecule is a shortened version of somatostatin's with a high affinity for these receptors.   view more (2008-09-22)

Lou Gehrig's protein found throughout brain, suggesting effects beyond motor neurons
Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease.   view more (2008-06-17)

New Editor-in-Chief for the Journal of Pathology
John Wiley is pleased to announce that Professor Simon Herrington has been appointed the new Editor-in-Chief for the Journal of Pathology.   view more (2002-02-13)

Mimicking a human disease in mice: a new model for the Parkinson related illness multiple system atrophy
In this month`s issue of EMBO Reports Kahle et al. describe how they genetically engineered a mouse to show pathological symptoms similar to those of human patients suffering from the neural disease Multiple System Atrophy (MSA), also known as Shy-Drager-Syndrome. The model could help researchers to develop and test new efficient drugs against... view more... (2002-06-06)

Imaging features of intraductal papillary mucinous neoplasms of the pancreas
The intraductal papillary mucinous neoplasms (IPMN) can evolve through all biological stages, from slight dysplasia to carcinoma.   view more (2009-09-16)

Drug commonly used for alcoholism curbs urges of pathological gamblers
A drug commonly used to treat alcohol addiction has a similar effect on pathological gamblers - it curbs the urge to gamble and participate in gambling-related behavior, according to a new research at the University of Minnesota.   view more (2008-06-16)

The UAB heads a European research project on proteases and pathological processes
A research group of the UAB Institute of Biotechnology and Biomedicine and the UAB Department of Biochemistry and Molecular Biology, directed by Francesc Xavier Avilés, is the coordinator of a European project aimed at studying proteases with fluorescent molecules that allow their monitoring in healthy and pathological situations.   view more (2007-07-18)
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