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Study reveals current multi-component vaccines may need reworking
Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS). view more (2009-05-08)
Using carbon nanotubes to seek and destroy anthrax toxin and other harmful proteins
Researchers at Rensselaer Polytechnic Institute have developed a new way to seek out specific proteins, including dangerous proteins such as anthrax toxin, and render them harmless using nothing but light. view more (2007-12-11)
Toothpick: New molecular tag IDs bone and tooth minerals
Enlisting an army of plant viruses to their cause, materials researchers at the National Institute of Standards and Technology (NIST) have identified a small biomolecule that binds specifically to one of the key crystal structures of the body-the calcium compound that is the basic building block of teeth and bone. With refinements, the researchers... view more... (2008-07-11)
Nanoparticle 'Smart Bomb' Targets Drug Delivery to Cancer Cells
Researchers at North Carolina State University have successfully modified a common plant virus to deliver drugs only to specific cells inside the human body, without affecting surrounding tissue. view more (2009-02-13)
New non-viral vector for gene therapy
A research team from the Universitat Autònoma de Barcelona has designed and built a recombinant protein (synthesised from artificially linked DNA segments) which is capable of releasing genes in specific cells. The new protein is ten times more efficient than the synthetic genetic vehicles in use until now and avoids the risks associated... view more... (2000-06-26)
Researchers 'notch' a victory toward new kind of cancer drug
Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed. view more (2009-11-12)
Impaired clearance of amyloid-beta causes vascular damage in Alzheimer's disease
New research suggests that accumulation of amyloid-β peptides in cerebral blood vessels, as opposed to the brain itself, may be a more important pathological mediator of Alzheimer's disease. view more (2005-07-21)
Folding Proteins on a Computer
Proteins only function when properly folded In order for enzymatic reactions to proceed correctly, the enzyme and substrate must fit together as precisely as a lock and key. The function of the enzyme and protein is determined by the structure of the latter. The chain of amino acids that makes up the protein thus has to fold in a very precise... view more... (2001-01-19)
Protein misprediction uncovered by new technique
A new bioinformatics tool is capable of identifying and correcting abnormal, incomplete and mispredicted protein annotations in public databases. view more (2008-08-27)
'Spaghetti' scaffolding could help grow skin in labs
Scientists are developing new scaffolding technology which could be used to grow tissues such as skin, nerves and cartilage using 3D spaghetti-like structures. view more (2009-10-16)
Scripps research team creates simple chemical system that mimics DNA
A team of Scripps Research scientists has created a new analog to DNA that assembles and disassembles itself without the need for enzymes. view more (2009-06-12)
LIAI finding gives boost to bioinformatics use in fighting disease
The use of computers to advance human disease research — known as bioinformatics — has received a major boost from researchers at the La Jolla Institute for Allergy & Immunology (LIAI), who have used it to successfully predict immune response to one of the most complex viruses known to man — the vaccinia virus, which is used... view more... (2006-06-16)
New target for Alzheimer's disease identified
Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed. view more (2008-05-07)
New strategy rapidly identifies cancer targets
In a step toward personalized medicine, Howard Hughes Medical Institute investigator Brian J. Druker and colleagues have developed a new technique to identify previously unknown genetic mutations that can trigger cancerous growth. view more (2006-07-17)
Study shows animal mating choices more complex than once thought
When female tiger salamanders choose a mate, it turns out that size does matter - tail size that is - and that's not the only factor they weigh. view more (2009-06-09)
Protein fragments sequenced in 68 million-year-old Tyrannosaurus rex
In a venture once thought to lie outside the reach of science, researchers from Harvard Medical School and Beth Israel Deaconess Medical Center have captured and sequenced tiny pieces of collagen protein from a 68 million-year-old Tyrannosaurus rex. view more (2007-04-13)
Fatty diet during pregnancy makes new cells in fetal brain that cause early onset obesity
A study in rats shows that exposure to a high-fat diet during pregnancy produces permanent changes in the offspring's brain that lead to overeating and obesity early in life, according to new research by Rockefeller University scientists. view more (2008-11-12)
Developing a modular, nanoparticle drug delivery system
There are two aspects to creating an effective drug: finding a chemical compound that has the desired biological effect and minimal side-effects and then delivering it to the right place in the body for it to do its job. view more (2007-10-08)
UQ research heralds vaccine technology breakthrough
Respiratory syncytial virus (RSV) infection is a widespread infant illness that has been linked to asthma and can be deadly but may be curable by the development of this new vaccine technology by the Sir Albert Sakzewski Virus Research Centre and The University of Queensland's Faculty of Biological and Chemical Sciences. view more (2007-05-09)
Prostate Cancer : Signature of a partnership agreement between Beaufour Ipsen and UroGene
The pharmaceutical group Beaufour Ipsen and the biopharmaceutical company UroGene have just signed a partnership agreement for the functional and clinical evaluation of a class of molecules in the field of prostate cancer. UroGene will be contributing its molecular genomic know-how, its biological and clinical expertise, and its biological... view more... (2002-07-17)
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