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Childhood obesity risk increased by newly-discovered genetic mutations, says study
Three new genetic variations that increase the risk of obesity are revealed in a new study, published today in the journal Nature Genetics. The authors suggest that if each acted independently, these variants could be responsible for up to 50% of cases of severe obesity. view more (2009-01-20)
Study advances evidence for receptor's role in alcohol pleasure and problems
A genetic variant of a receptor in the brain's reward circuitry heightens the stimulating effects of early exposures to alcohol and increases alcohol consumption, according to a new study by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). view more (2007-03-07)
A single water molecule acting as gate keeper
How do the bonds cells form with their environments rupture? What enables some cells to migrate? It is known since quite a while that cells can have complex mechanical interactions with their environments. Not only the biochemical but also the physical properties of their environment can thus have significant impact on cell behavior and even gene... view more... (2004-11-12)
A viral cloaking device
Viruses achieve their definition of success when they can thrive without killing their host. Now, biologists Pamela Bjorkman and Zhiru Yang of the California Institute of Technology have uncovered how one such virus, prevalent in humans, evolved over time to hide from the immune system. view more (2008-07-21)
Scientists identify prion's infectious secret
Researchers have known for decades that certain neurodegenerative diseases, such as mad cow disease or its human equivalent, Cruetzfeldt-Jakob disease, result from a kind of infectious protein called a prion. view more (2007-05-10)
UT Southwestern researchers pinpoint where 'bad' cholesterol levels are controlled
Researchers at UT Southwestern Medical Center have found that a protein responsible for regulating "bad" cholesterol in the blood works almost exclusively outside cells, providing clues for the development of therapies to block the protein's disruptive actions. view more (2009-04-17)
A 'grape' future for Alzheimer's disease research
With National Alzheimer's Awareness Month upon us, attention continues to focus on new approaches to cognitive health in an aging population. view more (2007-11-07)
Redox-active iron is a sensor of cognitive impairment associated with Alzheimer's disease
An innovative discovery has been reported that highlights the problems that oxidative stress resulting from iron cumulated in the human brain can generate in relation with the pathogenesis of Alzheimer's disease (AD), the brain disorder affecting almost 30 million throughout the world. view more (2008-04-07)
Compound in wine reduces levels of Alzheimer's disease-causing peptides
A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease. view more (2005-11-04)
Hormonal signaling in the brain: radical shift in understanding information processing
Two University of Edinburgh professors from the Centre for Integrative Physiology describe how "our understanding of how the brain processes information is undergoing a radical shift as we begin to recognize the implications of hormonal signaling systems within the brain itself," explained Gareth Leng. view more (2005-07-20)
Novel hydrogel systems for dentin regeneration
Dental caries, or tooth decay, continues to be the most prevalent infectious disease in the world, presenting significant public health challenges and socio-economic consequences. view more (2008-07-07)
Synthetic molecules may be less expensive alternative to therapeutic antibodies, researchers find
Researchers at UT Southwestern Medical Center have developed a simple and inexpensive method to screen small synthetic molecules and pull out a handful that might treat cancer and other diseases less expensively than current methods. view more (2008-04-07)
Leeches provide source for cardiovascular drugs
The leech has recently confirmed its biomedical interest for scientists by showing that it contains an extensive list of new potential molecules that may become useful tools in the treatment of cardiovascular diseases. view more (2005-10-26)
UC Davis researchers report new molecule that targets leukemia and lymphoma cells
UC Davis Cancer Center researchers have developed a novel peptide that binds to the surface of leukemia and lymphoma cells with extremely high affinity, specificity and stability, and demonstrates remarkable promise as a tool to help image tumors and deliver anti-cancer drugs. view more (2006-06-13)
Pea and whey in the control of high blood pressure
Hypertension or high blood pressure is a major risk factor for the development of cardiovascular diseases, which are the leading causes of morbidity and mortality in western society. It is estimated that 20% of the world's adult population suffers from hypertension. Recently, some functional foods have received considerable attention for their... view more... (2003-09-17)
Small peptide found to stop lung cancer tumor growth in mice
In new animal research done by investigators at Wake Forest University School of Medicine, scientists have discovered a treatment effective in mice at blocking the growth and shrinking the size of lung cancer tumors, one of the leading causes of cancer death in the world. view more (2009-08-27)
HU Ph.D. student wins award for 'natural protection' to reduce spread of Alzheimer's disease
Although numerous drugs have been developed over the years to alleviate the symptoms of Alzheimer's disease, there is still no real cure to halt this progressive, neurodegenerative disorder that causes premature death of nerve cells in the deep brain nuclei, leading to dementia and death. view more (2007-06-12)
Researchers reveal HIV peptide's possible pathway into the cell
Two theoretical physicists at Rensselaer Polytechnic Institute have uncovered what they believe is the long-sought-after pathway that an HIV peptide takes to enter healthy cells. The theorists analyzed two years of biocomputation and simulation to uncover a surprisingly simple mechanism describing how this protein fragment penetrates the cell... view more... (2008-01-18)
New 'OPAL Therapy' presents simple, cost-effective method of treating HIV infection
Australian researchers have unveiled a new immunotherapy technique to help prevent the progression from HIV infection to AIDS. Details of the simple, cost-effective technique are published May 2nd in the open-access journal PLoS Pathogens. view more (2008-05-05)
Protein shines light on cancer response
A technique that specifically "tags" tumors responding to chemotherapy may offer a new strategy for determining a cancer treatment's effectiveness within days of starting treatment, according to a new study by Vanderbilt-Ingram Cancer Center investigators. view more (2008-02-25)
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