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Can pathological techniques help identify primary colorectal signet ring cell carcinoma?
Primary colorectal signet ring cell carcinoma is a rare but distinctive malignancy of the large bowel. More than 96% of signet ring cell carcinomas arise in the stomach, with the rest arising from other primary organs.   view more (2008-05-21)

Researchers study new drug and indications for heated chemotherapy treatment
Studies have shown that surgery combined with Intraperitoneal Hyperthermic Chemotherapy (IPHC) can improve survival rates for select patients with peritoneal carcinoma (cancer of the lining of the abdominal cavity) that has spread from colorectal or appendix cancer.   view more (2008-03-17)

Preliminary Study Suggests Endomitriosis Could Contribute To Infertility
Authors of a research letter in this week's issue of THE LANCET provide preliminary evidence which suggests that the peritoneal fluid of women with endometriosis may play a significant role in reducing fertility. Endometriosis and infertility are known to be associated, but it is not known whether... view more (2002-10-16)

New Peritoneal Dialysis Diagnostic Discovered: Scientists Find Marker for Addressing Infection
Thanks to a discovery by scientists at Robarts Research Institute and The University of Western Ontario, patients undergoing peritoneal dialysis may soon be able to worry less about the risks of infection and lessen their hospital stays.   view more (2007-10-18)

Which is accurate, CT or MRI?
Paraaortic lymph node metastasis in patients with pancreatico-biliary carcinoma has been reported as a definite predictor of early recurrence and shorter survival term.   view more (2008-05-21)

Gastric cancer with 3 pathological features
Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma.   view more (2008-09-18)

A potential targets for the prevention or treatment of esophageal carcinoma
Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR.   view more (2008-10-29)

A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value.   view more (2008-05-21)

Removal of ovaries decreases risk of certain cancers for women at high-risk
Women with mutations in the BRCA1 or BRCA2 genes can significantly reduce their risk of certain types of cancer by having their ovaries removed.   view more (2006-07-12)

Study Examines Role of Helicobacter Pylori in Esophageal Cancer Development
Infection with bacteria that can cause peptic ulcers and distal stomach cancer may be associated with a reduced risk of a type of esophageal cancer called adenocarcinoma, according to a study in the March 3 issue of the Journal of the National Cancer Institute. However, that same study found that... view more (2004-03-03)

The small cell neuroendocrine carcinoma of the ampulla of vater
Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed.   view more (2008-09-25)

What induce local recurrence of rectal carcinoma?
It is well known that local recurrence is the most important prognostic factor of rectal carcinoma. However, even after undergoing radical resection of primary tumors and lymph nodes, about 4%-50% of patients with rectal carcinoma were reportedly with local recurrence.   view more (2008-09-22)

Incidence of nonmelanoma skin cancer on the rise among young adults
A new study from Minnesota finds the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40, according to an article in the August 10 issue of JAMA.   view more (2005-08-10)

Is the spleen able to prohibit tumor cell proliferation?
Primary and metastatic tumors of the spleen are described as unusual, excluding involvement by lymphoma. Indeed, isolated splenic metastasis from colorectal carcinoma is not a common occurrence. Its rareness has been hypothetically explained by several characteristics of the spleen, such as... view more (2007-10-17)

Novel marker of colon cancer
Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide.   view more (2008-10-24)

Report calls for using heated chemotherapy after colon cancer surgery to optimize patient survival
There is new hope for some of the most seriously ill colon cancer patients today, following the release of a consensus statement by 72 leading oncology surgeons from 14 countries, including the United States.   view more (2006-11-06)

Angiotensin inhibitors and receptor blockers linked to lower risk of nonmelanoma skin cancer
The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) was associated with a reduced risk of basal cell or squamous cell skin cancers in U.S. veterans, researchers report in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

New study reports increased response to therapy with no added toxicity in treatment of recurrent ovarian cancer
In a study released today at the Society of Gynecologic Oncologists 37th Annual Meeting on Women's Cancer, researchers found the addition of thalidomide to topotecan for the treatment of recurrent ovarian cancer significantly increases the response to therapy and the duration of progression free... view more (2006-03-27)

How is H pylori adhesion to gastric cells associated with MUC1 mucin VNTR size?
The Gram negative bacterium H pylori is involved in the pathogenesis of several gastrointestinal diseases, ultimately leading to gastric carcinoma. Adhesion of the bacteria to the gastric mucosa is an essential step for colonization and infection.   view more (2008-03-19)

Ultraviolet B light exposure associated with increased risk of skin cancer
A decreased ability to repair chromosomal damage caused by exposure to ultraviolet B (UV-B) radiation in test tubes may be associated with an increased risk of the common skin cancers basal cell carcinoma and squamous cell carcinoma, but not of melanoma.   view more (2005-12-21)

How to select anti-hepatitis B virus agents for drug-resistance patients?
HBV infection may lead to acute liver disease, chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma. Over 350 million people worldwide are estimated to be infected chronically by HBV and are therefore at risk of liver failure, cirrhosis, or hepatocellular carcinoma.   view more (2008-09-25)

Landmark Dialysis Study Findings Could Greatly Simplify Treatment of Kidney Disease with Peritoneal Dialysis
Montreal, Canada, June 29, 2001 - Data presented from the largest randomized controlled clinical trial ever completed in dialysis patients suggest that peritoneal dialysis (PD), a flexible home-based dialysis treatment for people with chronic kidney failure, might have far broader applicability... view more (2001-06-29)

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?
Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.   view more (2008-03-18)

Researchers discover scent of skin cancer
According to new research from the Monell Center, odors from skin can be used to identify basal cell carcinoma, the most common form of skin cancer. The findings, presented at the 236th meeting of the American Chemical Society, may open doors to development of new methods to detect basal cell... view more (2008-08-21)

Study provides clues to prevent spread of ovarian cancer
A drug that blocks production of an enzyme that enables ovarian cancer to gain a foothold in a new site can slow the spread of the disease and prolong survival in mice, according to a study by researchers from the University of Chicago Medical Center, but only if the drug is given early in the... view more (2008-03-14)

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