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UCSB researchers discover shape matters to macrophages
Researchers at UC Santa Barbara have made a surprising discovery: phagocytosis depends more on particle shape than size.   view more (2006-03-22)

Discovery in the evolution of the immune system absorbing cells
Led by Dr J Oriol Sunyer, of the Faculty of Veterinary Medicine at the University of Pennsylvania, and formed by researchers from Philadelphia, St Louis and Idaho (USA) and by Dr Lluís Tort of the Universitat Autònoma de Barcelona, the group has been able to show that B cells in fish as well as... view more (2006-10-05)

St. Jude finds link between cellular defense processes, showing how cancer cells survive
St. Jude Children's Research Hospital investigators have discovered that immune system cells that engulf and destroy germs in the body enlist help for this task from a common housekeeping mechanism that most cells use to keep their interiors healthy, a finding that is likely to help researchers... view more (2007-12-20)

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells
French scientists have learned how Listeria monocytogenes, which causes a major food-borne illness, commandeers cellular transport machinery to invade cells and hide from the body's immune system.   view more (2005-08-22)

Case Western Reserve University researchers find protein associated with brain cell death
Neuroscientists at the Case Western Reserve University School of Medicine have found evidence of which protein in the brain's immune cells triggers a cascade of reactions that produces unregulated free radical production that eventually leads to the neural cell death found in Alzheimer's disease.   view more (2006-07-19)

Proteomics Study Yields Clues As To How Tuberculosis Might Be Thwarting The Immune System
A link between the immune system and the self-cleaning system by which biological cells rid themselves of obsolete or toxic parts may one day yield new weapons in the fight against tuberculosis and other deadly infectious diseases.   view more (2008-11-06)

Invertebrate immune systems are anything but simple, conference finds
A hundred years since Russian microbiologist Elie Metschnikow first discovered the invertebrate immune system, scientists are only just beginning to understand its complexity.   view more (2007-06-21)

'Killer' B cells provide new link in the evolution of immunity
Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered a unique evolutionary link between the most primitive innate form of immune defense, which has survived in fish, to the more advanced, adaptive immune response present in humans and other mammals.   view more (2006-10-04)

GSF scientists examine the role of small sputum macrophages in the widespread disease chronic obstructive bronchitis
COPD (chronic obstructive pulmonary disease) is one of the most common fatal diseases worldwide. In Germany alone, there are about 3-5 million patients affected. COPD includes both chronic obstructive bronchitis and emphysema. Both represent irreversible changes of the central and lower respiratory... view more (2005-01-10)

Stealth particles to target tumors
Stealth nano particles may some day target tumor cells and deliver medication to specific body locations, according to Penn State chemical engineers.   view more (2005-09-01)

A candidate gene for familial idiopathic pulmonary fibrosis identified
ELMOD2-gene is a prime candidate gene for familial idiopathic pulmonary fibrosis, suggests the recent study published by the researchers at the University and University Hospital of Helsinki, Finland.   view more (2006-06-29)

A key antibody, IgG, links cells' capture and disposal of germs
Scientists have found a new task managed by the antibody that's the workhorse of the human immune system: Inside cells, Immunoglobulin G (IgG) helps bring together the phagosomes that corral invading pathogens and the potent lysosomes that eventually kill off the germs.   view more (2006-11-14)

Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles.   view more (2007-06-27)

New strategy for protecting brain against Alzheimer's disease: Enhancing the innate immune system
The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer's disease have an immune defect making it difficult to clean away these wastes.   view more (2005-06-10)

New, more direct pathways from outside the cell-to-cell nuclei discovered
A team of Brooklyn College researchers has shattered a long-held belief that no direct pathway exists between material outside of a cell and the cell nucleus. (The cell is the smallest metabolically functional unit of life.)   view more (2007-08-13)

University of Pennsylvania Researchers Discover "Killer" B Cells; New Link in the Evolution of Immunity
Researchers from the University of Pennsylvania School of Veterinary Medicine have discovered a unique evolutionary link between the immune systems of fish and mammals in the form of a primitive version of B cells, white blood cells of the immune system.   view more (2006-09-21)

MS patients have higher spinal fluid levels of suspicious immune molecule
A protein that helps keep immune cells quiet is more abundant in the spinal fluid of patients with multiple sclerosis (MS), further boosting suspicion that the protein, TREM-2, may be an important contributor to the disease.   view more (2008-09-30)

Research shows NPD1 protects a key component of vision
Two papers to be published in the Early Edition online of the Proceedings of the National Academy of Sciences (PNAS) the week of July 30-August 3, 2007 report findings that demonstrate that neuroprotectin D1 (NPD1) protects against damage to retinal pigment epithelial (RPE) cells and identifies an... view more (2007-07-31)

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