Phosphorylation Current Events | Phosphorylation News | 2
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Researchers figure out what makes a simple biological clock tick
An interdisciplinary team of researchers at Vanderbilt University has analyzed the simplest known biological clock and figured out what makes it tick. view more (2007-03-27)
Brown Researchers Make Major Signal Transduction Discovery
The chemical process known as acetylation plays a central role in cytokine receptor signal transduction - a fundamental biochemical cascade inside cells that controls the activity of antiviral and tumor-suppressing genes. view more (2007-10-05)
Is transforming growth factor-beta involved in intestinal wound healing?
Migration of colonic lamina propria fibroblasts (CLPF) plays an important role during the progression of fibrosis and fistulae in Crohn's disease. Transforming growth factor- beta (TGF- beta) is involved in the regulation of cell migration, cell differentiation, extracellular matrix deposition, and immune responses. view more (2009-03-31)
Mutation improves memory, may lead to memory-enhancing pill
A mind-altering mutation in mice results in an enhanced long-term memory, researchers report in the April 6, 2007 issue of the journal Cell, published by Cell Press. These findings point to a potential target for the development of a drug to treat memory loss, according to the researchers. view more (2007-04-06)
Enzyme complex thought to promote cancer development can also help prevent it
In a case of basic science detective work, researchers at The University of Texas M. D. Anderson Cancer Center have solved the puzzle of the "inconsistent biomarker" and, in the process, may have discovered an agent that can suppress cancer development. view more (2005-10-14)
Scientists discover that three molecules may be developed into new Alzheimer's drugs
A team of scientists has discovered three molecules -- from a search of 58,000 compounds -- that appear to inhibit a key perpetrator of Alzheimer's disease. view more (2005-07-25)
Major 'missed' biochemical pathway emerges as important in virtually all cells
A new study by Duke University researchers provides more evidence that the nitric oxide (NO) system in the life of a cell plays a key role in disease, and the findings point to ways to improve treatment of illnesses such as heart disease and cancer. view more (2008-05-23)
Pathogens use previously undescribed mechanism to sabotage host immune system
New research identifies a previously unknown enzymatic mechanism that subverts the early host immune response and promotes pathogenicity by manipulating a common signaling pathway in host cells. view more (2007-12-10)
Keeping the body in sync — The stability of cellular clocks
A study in Switzerland uses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular environment. view more (2007-03-13)
New alternative to biopsy detects subtle changes in cancer cells, Stanford study shows
A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine. view more (2009-04-13)
The food-energy cellular connection revealed
Our body's activity levels fall and rise to the beat of our internal drums-the 24-hour cycles that govern fundamental physiological functions, from sleeping and feeding patterns to the energy available to our cells. view more (2009-10-16)
New Piece Found in the Puzzle of Epigenetics
A team of scientists led by Professor Dirk Eick of Helmholtz Zentrum München has identified the enzyme TFIIH kinase as an important factor in the epigenetic regulation of the cell nucleus enzyme RNA polymerase II. view more (2009-06-17)
Mouse gene suppresses Alzheimer's plaques and tangles
Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. view more (2009-11-12)
New evidence of how high glucose damages blood vessels could lead to new treatments
New evidence of how the elevated glucose levels that occur in diabetes damage blood vessels may lead to novel strategies for blocking the destruction, Medical College of Georgia researchers say. view more (2009-05-12)
Out-of-whack protein may boost Parkinson's
A single change in a protein may play a role in whether someone develops Parkinson's disease, say University of Florida Genetics Institute researchers writing in a recent issue of the Proceedings of the National Academy of Sciences. view more (2008-02-27)
Chromatin remodeling complex connected to DNA damage control
When molecular disaster strikes, causing structural damage to DNA, players in two important pathways talk to each other to help contain the wreckage, scientists at The University of Texas M. D. Anderson Cancer Center report in the August edition of Cell. view more (2007-08-10)
New hope for treatment of neurodegenerative disorder
Researchers from the University of Southern California have taken an important first step toward protecting against Huntington disease using gene therapy. view more (2009-04-21)
Study reveals how blood flow force prevents clogged arteries
Machines on cell surfaces, mechanical and lifeless as bed springs, protect blood vessels by responding to blood flow force, according to research published today in the Journal of Cell Biology. view more (2008-08-26)
Kids with autism may have gene that causes muscle weakness
Some kids with autism may have a genetic defect that affects the muscles, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12-19, 2008. view more (2008-04-14)
'Memory molecule' stores memories in neocortex
The "memory storage molecule" - PKMzeta - maintains long-term memories in the neocortex and its presence is continually required in order for the memory to endure, according to a finding by researchers at the Weizmann Institute in Rehovot, Israel and SUNY Downstate Medical Center in Brooklyn, New York. view more (2007-08-17)
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