Phosphorylation Current Events | Phosphorylation News | 3
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Drug that interrupts a key stage of cell division shows promise for advanced solid tumors One of the first studies to investigate the effects of a new anti-cancer drug in patients with advanced or metastatic solid tumours has shown that it is capable of halting progression of the disease, and the study has provided the first proof of the drug's mechanism of action. view more (2006-11-08)
Simplest circadian clocks operate via orderly phosphate transfers Researchers at Harvard University and the Howard Hughes Medical Institute have found that a simple circadian clock found in some bacteria operates by the rhythmic addition and subtraction of phosphate groups at two key locations on a single protein. view more (2007-10-05)
Vax and Pax: Taking turns to build an eye Opposing ball clubs don't take the field at the same time, and neither do teams of proteins responsible for creating the eye. While one team builds the retina, in adjacent cellular turf the opponents are busy constructing the cord that carries visual signals to the brain. And these guys aren't supposed to mingle. view more (2006-10-16)
Study: Brain connections strengthen during waking hours, weaken during sleep Most people know it from experience: After so many hours of being awake, your brain feels unable to absorb any more-and several hours of sleep will refresh it. view more (2008-01-21)
Lithium chloride slows onset of skeletal muscle disorder A new UC Irvine study finds that lithium chloride, a drug used to treat bipolar disorder, can slow the development of inclusion body myositis, a skeletal muscle disease that affects the elderly. view more (2008-03-19)
Tribble 3 can induce non-alcoholic fatty liver disease? Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. view more (2009-06-11)
Emory researchers identify signaling protein for multiple myeloma Researchers at Emory University's Winship Cancer Institute are the first to discover a mechanism that plays a critical role in the multiple myeloma cell cycle and survival. view more (2007-09-11)
New mechanism for nutrient uptake discovered Biologists at the Carnegie Institution's Department of Plant Biology have discovered a new way that plant cells govern nutrient regulation—neighboring pore-like structures at the cell's surface physically interact to control the uptake of a vital nutrient, nitrogen. view more (2007-02-12)
A molecular basis for selective therapeutic intervention in Alzheimer's disease Alzheimer's disease, a complex neurological disorder, has as one of its hallmarks the presence of senile plaques in the brains of affected individuals. view more (2005-10-07)
Unraveling how cells respond to low oxygen Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. view more (2009-08-06)
Link identified between age, cardiovascular disease Researchers in the Linus Pauling Institute at Oregon State University have discovered a fundamental mechanism that causes aging blood vessels to lose their elasticity - a literal "hardening of the arteries" that is often a prelude to high blood pressure and cardiovascular disease. view more (2006-11-06)
E. coli persists against antibiotics through HipA-induced dormancy Bacteria hunker down and survive antibiotic attack when a protein flips a chemical switch that throws them into a dormant state until treatment abates, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan.16 edition of Science. view more (2009-01-16)
Gene that makes people 'early to bed and early to rise' demystified The recent discovery that a mutant "clock" gene made some people "early to bed and early to rise," a condition known as familial advanced sleep phase syndrome (FASPS), offered one of the first glimpses into the genetic basis of sleep in humans. view more (2007-01-12)
Building memories with actin Memories aren't made of actin filaments. But their assembly is crucial for long-term potentiation (LTP), an increase in synapse sensitivity that researchers think helps to lay down memories. view more (2009-07-13)
Membrane research opens window to benefits for plants, humans A wilting, water-starved houseplant and flood-covered crops have something in common. That knowledge, gleaned from spinach and researchers on two continents, potentially could open the gate to advances in both plant and human health. view more (2005-12-21)
Scripps Florida scientists develop a process to disrupt hepatitis C virion production HCV is a significant human pathogen, infecting more than three percent of the world's population. The incidence of infection in the United States has been estimated to be as high as 4 million cases. view more (2008-03-24)
Telling axons where to go - and grow In a recent study, Dr. Ingolf Bach and colleagues from the University of Massachusetts Medical School, Worcester and the University of Hamburg (Germany) describe a novel role for the ubiquitin/proteosome protein degradation pathway in the regulation of local actin dynamics in neurons. view more (2005-10-03)
MU Researchers Make Discovery in Molecular Mechanics of Phototropism In a paper published in the Journal of Biological Chemistry, scientists at the University of Missouri-Columbia reported molecular-level discoveries about the mechanisms of phototropism, the directional growth of plants toward or away from light. view more (2007-07-09)
Launch of Dundee Diabetes Research Centre The diabetes laboratories at the University of Dundee have been awarded Centre status to promote communication amongst the research and clinical groups and to raise public awareness of their work. view more (2005-04-18)
Discovery of the cell's water gate may lead to new cancer drugs The flow of water into and out from the cell may play a crucial role in several types of cancer. Scientists at the University of Gothenburg have now found the gate that regulates the flow of water into yeast cells. view more (2009-06-17)
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