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Study implicates protein as a trigger of advanced prostate cancer recurrence
Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.   view more (2007-05-09)

Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT).   view more (2006-07-25)

UC Santa Barbara scientists clarify molecular basis of interferon action
Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans.   view more (2007-07-20)

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection
As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.   view more (2008-04-07)

How Rett Syndrome mutation targets the brain
Researchers have pinpointed why mutations that cause Rett Syndrome (RTT)-among the leading causes of mental retardation in females-specifically target the brain rather than other body tissues.   view more (2006-10-19)

Funnel in the eye: Signal focusing increases photosensitivity
In poor light the eyes of mice react like some digital cameras: they reduce their resolution while at the same time increasing their sensitivity. Specialists in the retina focus the information of several light sensor cells for this purpose.   view more (2006-11-03)

Researchers identify new, cancer-causing role for protein
The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science.   view more (2009-08-28)

A potential approach to treatment of hepatitis B virus infection
Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.   view more (2008-09-10)
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