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Homoeopathy is not an effective treatment for asthma
Homoeopathic remedies are no better than placebo for the treatment of asthmatic patients who are allergic to house dust mite, but there is a difference in response between homoeopathy and placebo, concludes a study in this week's BMJ. The research team identified 242 asthmatic people allergic to... view more (2002-02-27)

Homeopathy no better than placebo for improving quality of life in childhood asthma
Homeopathic remedies, which are often used to improve the quality of life of asthmatic children, are no better than placebo, finds a study in Thorax.   view more (2003-03-28)

Patients should be more involved in the clinical trial process
Patients should be treated as participants rather than subjects during clinical trials, suggest researchers in this week’s BMJ.   view more (2002-12-04)

Codeine may be no cure for cough
Scientists at the University of Manchester's North West Lung Centre have found that codeine-a standard ingredient in cough remedies - could be no more effective than an inactive placebo compound at treating cough.   view more (2006-05-19)

PENTOXIFYLLINE BENEFICIAL FOR TREATING LEG ULCERS (p 1550)
Results of a systematic review in this week's issue of THE LANCET suggest that the drug pentoxifylline could be effective in the treatment of leg ulcers, either in addition to compression therapy, or as sole treatment when compression therapy is not effective. Venous leg ulcers are associated with... view more (2002-05-01)

Brain region central to placebo effect identified
Researchers have pinpointed a brain region central to the machinery of the placebo effect-the often controversial phenomenon in which a person's belief in the efficacy of a treatment such as a painkilling drug influences its effect.   view more (2007-07-19)

HYPERICUM EXTRACT AS EFFECTIVE AS COMMON ANTI-DEPRESSANT MEDICATION
Professor Michael Philipp from Landshut Bezirkskrankenhaus [district hospital] along with colleagues from Nuremberg and Berlin studied the efficacy and safety of hypericum extract as compared with imipramine (which is a commonly prescribed anti-depressant in Germany) and placebo in 263 patients... view more (1999-12-08)

Antibiotic Could Offer Promise For Treatment Of Cystic Fibrosis
The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of THE LANCET. Cystic fibrosis is a severe genetic disorder-the most commonly recessively inherited disorder in... view more (2002-09-25)

All placebos not created alike
The debate about the existence of a placebo effect has heated up over the past year as more and more lab experiments are detecting immediate physiological responses to placebos.   view more (2006-02-01)

Study evaluates the effectiveness of Aripiprazole in adolescents with schizophrenia
In a six-week study in adolescents (13-17 years old) with schizophrenia, the Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company (NYSE: BMY) atypical antipsychotic aripiprazole demonstrated significant improvement compared to placebo on the primary efficacy endpoint, Positive and... view more (2007-05-24)

Placebo study frames depression treatment puzzle
Treating major depression can be quite a puzzle, and a newly published UCLA study suggests medication is just one of many potential pieces.   view more (2006-08-01)

Over the counter cough medicines may be an unnecessary expense
There is little evidence for or against the effectiveness of over the counter cough medicines for adults, and they may be an unnecessary expense, finds a study in this week's BMJ. Researchers at the University of Bristol reviewed 15 trials, involving over 2,000 patients, that compared oral over the... view more (2002-02-06)

Medication shows promise as a treatment for alcohol dependence
Alcohol-dependent patients who received the medication topiramate had fewer heavy drinking days, fewer drinks per day and more days of continuous abstinence than those who received placebo.   view more (2007-10-10)

Popular herbal remedy fails effectiveness test for tinnitus
Researchers at the University of Birmingham identified 1,121 healthy people with tinnitus. 559 received 12 weeks treatment with Ginkgo biloba extract and 562 received a placebo. Tinnitus was assessed using several questionnaires - before treatment began, after 4 and 12 weeks of treatment, and 2... view more (2001-01-10)

Pramipexole delivered sustained efficacy in clinical trial of patients with Restless Legs Syndrome
Two large, randomised, placebo-controlled studies presented at the inaugural conference of the World Association of Sleep Medicine (WASM; Berlin, Germany) in October demonstrate that pramipexole delivered both short-term and sustained efficacy in patients suffering from Restless Legs Syndrome... view more (2005-12-12)

Researchers discover treatment for spinal cord injury pain
Spinal cord injury patients with moderate to severe nerve pain experienced less pain and in some cases no pain while taking the drug pregabalin.   view more (2006-11-28)

Inhaled Steroids Could Be New Option For Treating Mild Asthma (p 1071)
Results of a large international study in this week's issue of THE LANCET provide strong evidence that inhaled steroids could substantially reduce illness associated with mild asthma. Previous research has not established whether steroids could be effective in controlling mild asthma, mainly... view more (2003-03-26)

First multinational study of Tocilizumab reports in
Nearly half (43.9%) of rheumatoid arthritis (RA) patients receiving tocilizumab 8mg/kg, in addition to ongoing methotrexate therapy experienced a 50% (ACR50) improvement in symptoms at 24 weeks and more than one fifth achieved a 70% symptom improvement.   view more (2007-06-18)

Stanford study finds no conclusive benefit from treating kleptomania
A small clinical trial of a medication to treat kleptomania has failed to find any conclusive benefit for patients with the impulsive stealing disorder, according to researchers at the Stanford University School of Medicine.   view more (2007-03-14)

H Pylori Eradication Reduces Risk Of Peptic Ulcers For Patients Taking Non-steroidal Anti-inflammatory Drugs
Screening and treatment for infection caused by the gastrointestinal bacterium Helicobacter pylori could substantially reduce the risk of ulcers for patients starting long-term non-steroidal anti-inflammatory drug (NSAID) treatment, conclude authors of a study in this week's issue of THE LANCET. A... view more (2002-01-02)

Iron supplements may relieve unexplained tiredness in young women
Unexplained tiredness is common in young women. In this week's BMJ, researchers find that non-anaemic women with fatigue may benefit from taking an iron supplement. The study took place in Switzerland and involved 136 women aged 18 to 55 who consulted a doctor with fatigue, but who were not... view more (2003-05-22)

Early Promise Of New Treatment To Reduce Infection Associated With Chemotherapy (P 275)
Authors of a fast-track study in this week's issue of THE LANCET propose an alternative to antibiotics to treat infection associated with the use of chemotherapy for patients with blood cancer. The toxic effects of chemotherapy cause organisms in the gut to migrate to the bloodstream, frequently... view more (2003-01-23)

Low dose aspirin does not protect women against cognitive decline
Taking low dose aspirin does not protect older women against cognitive decline, finds a large study published on bmj.com today.   view more (2007-04-27)

Does gingko biloba affect memory?
Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems.   view more (2008-02-28)

Study finds doxycycline effective against filariasis in Southeast Asia
Doxycycline alone is more effective against the most common form of filariasis in Southeast Asia than the standard treatment, with significantly fewer side effects, according to a new study published in the May 1 issue of Clinical Infectious Diseases and currently available online.   view more (2008-04-10)
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