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Homoeopathy is not an effective treatment for asthma
Homoeopathic remedies are no better than placebo for the treatment of asthmatic patients who are allergic to house dust mite, but there is a difference in response between homoeopathy and placebo, concludes a study in this week's BMJ. The research team identified 242 asthmatic people allergic to house dust mite. Participants received either... view more... (2002-02-27)

Homeopathy no better than placebo for improving quality of life in childhood asthma
Homeopathic remedies, which are often used to improve the quality of life of asthmatic children, are no better than placebo, finds a study in Thorax.   view more (2003-03-28)

Patients should be more involved in the clinical trial process
Patients should be treated as participants rather than subjects during clinical trials, suggest researchers in this week’s BMJ.   view more (2002-12-04)

Codeine may be no cure for cough
Scientists at the University of Manchester's North West Lung Centre have found that codeine-a standard ingredient in cough remedies - could be no more effective than an inactive placebo compound at treating cough.   view more (2006-05-19)

PENTOXIFYLLINE BENEFICIAL FOR TREATING LEG ULCERS (p 1550)
Results of a systematic review in this week's issue of THE LANCET suggest that the drug pentoxifylline could be effective in the treatment of leg ulcers, either in addition to compression therapy, or as sole treatment when compression therapy is not effective. Venous leg ulcers are associated with circulatory disorders and are common among people... view more... (2002-05-01)

Brain region central to placebo effect identified
Researchers have pinpointed a brain region central to the machinery of the placebo effect-the often controversial phenomenon in which a person's belief in the efficacy of a treatment such as a painkilling drug influences its effect.   view more (2007-07-19)

HYPERICUM EXTRACT AS EFFECTIVE AS COMMON ANTI-DEPRESSANT MEDICATION
Professor Michael Philipp from Landshut Bezirkskrankenhaus [district hospital] along with colleagues from Nuremberg and Berlin studied the efficacy and safety of hypericum extract as compared with imipramine (which is a commonly prescribed anti-depressant in Germany) and placebo in 263 patients with moderate depression.   view more (1999-12-08)

Antibiotic Could Offer Promise For Treatment Of Cystic Fibrosis
The antibiotic azithromycin could offer some benefit to people with cystic fibrosis if they do not respond to conventional treatment, suggest authors of a study in this week's issue of THE LANCET. Cystic fibrosis is a severe genetic disorder-the most commonly recessively inherited disorder in white populations. Treatment is limited, and aimed at... view more... (2002-09-25)

All placebos not created alike
The debate about the existence of a placebo effect has heated up over the past year as more and more lab experiments are detecting immediate physiological responses to placebos.   view more (2006-02-01)

Study evaluates the effectiveness of Aripiprazole in adolescents with schizophrenia
In a six-week study in adolescents (13-17 years old) with schizophrenia, the Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company (NYSE: BMY) atypical antipsychotic aripiprazole demonstrated significant improvement compared to placebo on the primary efficacy endpoint, Positive and Negative Syndrome Scale (PANSS) Total Score.   view more (2007-05-24)

Placebo study frames depression treatment puzzle
Treating major depression can be quite a puzzle, and a newly published UCLA study suggests medication is just one of many potential pieces.   view more (2006-08-01)

Over the counter cough medicines may be an unnecessary expense
There is little evidence for or against the effectiveness of over the counter cough medicines for adults, and they may be an unnecessary expense, finds a study in this week's BMJ. Researchers at the University of Bristol reviewed 15 trials, involving over 2,000 patients, that compared oral over the counter cough medicines with placebo in adults... view more... (2002-02-06)

UCLA scientists present first genetic evidence for why placebos work
Placebos are a sham - usually mere sugar pills designed to represent "no treatment" in a clinical treatment study. The effectiveness of the actual medication is compared with the placebo to determine if the medication works.   view more (2009-07-21)

Medication shows promise as a treatment for alcohol dependence
Alcohol-dependent patients who received the medication topiramate had fewer heavy drinking days, fewer drinks per day and more days of continuous abstinence than those who received placebo.   view more (2007-10-10)

Pain relieving effects of acupuncture are limited
The pain relieving effects of acupuncture compared with placebo are small and seem to lack clinical relevance, according to a study published on bmj.com today.    view more (2009-01-28)

Popular herbal remedy fails effectiveness test for tinnitus
Researchers at the University of Birmingham identified 1,121 healthy people with tinnitus. 559 received 12 weeks treatment with Ginkgo biloba extract and 562 received a placebo. Tinnitus was assessed using several questionnaires - before treatment began, after 4 and 12 weeks of treatment, and 2 weeks after treatment ended. They found that Ginkgo... view more... (2001-01-10)

Pramipexole delivered sustained efficacy in clinical trial of patients with Restless Legs Syndrome
Two large, randomised, placebo-controlled studies presented at the inaugural conference of the World Association of Sleep Medicine (WASM; Berlin, Germany) in October demonstrate that pramipexole delivered both short-term and sustained efficacy in patients suffering from Restless Legs Syndrome (RLS)1,2 enrolled in these trials.   view more (2005-12-12)

News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute.   view more (2009-10-13)

Infliximab may help prevent post-operative Crohn's disease recurrence
The administration of infliximab after intestinal resective surgery was found to be effective at preventing endoscopic and histological recurrence of Crohn's disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.   view more (2009-02-02)

Researchers discover treatment for spinal cord injury pain
Spinal cord injury patients with moderate to severe nerve pain experienced less pain and in some cases no pain while taking the drug pregabalin.   view more (2006-11-28)
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