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Early signs that statins could help in treatment of rheumatoid arthritis (pp 2011, 2015)
Results of a UK study in this week's issue of THE LANCET suggest that the anti-inflammatory effect of statins (a class of cholesterol-lowering drugs) could be effective in relieving symptoms of rheumatoid arthritis.    The inflammatory nature of rheumatoid arthritis puts sufferers at an increased risk of cardiovascular disease.... view more... (2004-06-16)

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep
A new study at the Université de Montréal has concluded that people drinking coffee to get through a night shift or a night of studying will strongly hurt their recovery sleep the next day.   view more (2006-10-03)

Use of amino acid supplement following a heart attack provides no benefit, may be harmful
Use of the amino acid supplement L-arginine following a heart attack does not improve certain cardiac functions and measurements and may be associated with an increased risk of death.   view more (2006-01-04)

Hope for patients with COPD
For the first time, a drug therapy appears to reduce lung function loss in patients with moderate to severe chronic obstructive pulmonary disease (COPD), according to the results of a randomized, double-blind, placebo-controlled trial in 42 countries.   view more (2008-08-15)

Genetic variation affects smoking cessation treatment
Mark Twain boasted that it was easy to quit smoking because he did it every day. We now may have the beginnings of understanding why some people find it so difficult to stop smoking even when they are in treatment for this problem.   view more (2007-09-21)

Growth hormone treatment for HIV patients improves abdominal fat, but worsens glucose level
For human immunodeficiency virus (HIV)-infected patients with treatment-related abdominal obesity and growth hormone deficiency, receiving low-dose growth hormone resulted in improvement in fat and blood pressure measurements but worsened glucose levels.   view more (2008-08-04)

Study shows prostate cancer vaccine linked to longer survival
A University of California, San Francisco study has found that men with advanced, often untreatable prostate cancer who received a therapeutic cancer vaccine went on to survive longer than those receiving a placebo.   view more (2006-06-30)

Drug fends off kidney cancer progression
New data from an international, multicenter Phase III clinical trial has found that the experimental targeted therapy everolimus (RAD001) significantly delays cancer progression in patients with metastatic kidney cancer whose disease had worsened on other treatments.   view more (2008-05-19)

LONG-TERM BENEFITS OF GLUCOSAMINE SULPHATE FOR OSTEOARTHRITIS (pp 247, 251)
The symptoms and changes to joint structure associated with osteoarthritis could be moderated by the long-term effects of glucosamine sulphate, conclude investigators in a study published in this week's issue of THE LANCET. Osteoarthritis is a major cause of disability and is among the most frequent forms of musculoskeletal disorders. Several... view more... (2001-01-24)

New topical spray may treat premature ejaculation
PSD502, a new topical spray, is a safe and effective treatment for premature ejaculation. Researchers presented data on the spray's efficacy during a presentation of their randomized, Phase 3, double-blind, placebo-controlled study at the 104th Annual Scientific Meeting of the American Urological Association (AUA).   view more (2009-04-27)

Early Promise For Dementia Drug (pp 1265, 1283)
Encouraging short-term results of a randomised trial in this week's issue of THE LANCET suggest that the drug galantamine could offer therapeutic benefits to people with Alzheimer's disease with cerebrovascular disease and in those with probable vascular dementia. Vascular dementia-dementia caused by multiple strokes or other cerebrovascular... view more... (2002-04-10)

Bone marrow cell therapy may be beneficial for patients with ischemic heart disease
The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle.   view more (2009-05-20)

Hormone patch may provide some increase in sexual desire in menopausal women
A testosterone patch may produce modest increases in sexual desire and frequency of satisfying sexual experiences in women who develop distressful, low sexual desire following hysterectomy and removal of the fallopian tubes and ovaries, according to a study in the July 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.   view more (2005-07-26)

Rheumatoid arthritis could be prevented if the timing is right
Patients diagnosed with 'undifferentiated rheumatoid' arthritis could actually have their disease outlook changed significantly if treatment is given at the right time.   view more (2006-06-22)

Migraine treatment also appears effective for cluster headaches
Zolmitriptan nasal spray, used to treat migraine headaches, also may be safe and effective in treating painful cluster headaches.   view more (2006-09-12)

Tadalafil may effectively treat symptoms of BPH-LUTS in addition to erectile dysfunction
Tadalafil may improve lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH). Researchers from Nashville, Dallas, San Antonia and Indianapolis will present these findings during the 104th Annual Scientific Meeting of the American Urological Association (AUA).    view more (2009-04-27)

Botanicals have no effect on hot flashes or cognition: Study
Two studies conducted by researchers at the University of Illinois at Chicago and Northwestern University have found that commonly used botanicals do not have an effect on hot flashes or on cognitive function in menopausal women.   view more (2009-08-07)

NEW DRUG TREATMENT COULD PROVIDE LONG-TERM BENEFIT FOR HEART-ATTACK PATIENTS (p 1385)
Patients with acute myocardial infarction (heart attack), complicated by left-ventricular systolic dysfunction, could benefit from the ß-blocker carvedilol, conclude authors of a study in this week's issue of THE LANCET. In a randomised, placebo-controlled trial, this drug reduced the frequency of death from all causes, death from... view more... (2001-05-03)

NEW THERAPEUTIC APPROACH TO CORONARY STENTING (p 2037)
Patients given stent implantation to treat coronary heart disease could benefit from a new therapeutic approach with the platelet glycoprotein IIb/IIIa inhibitor eptifibatide, concludes research published in this week's issue of THE LANCET. The platelet glycoprotein IIb/IIIa inhibitors are potent inhibitors of blood clotting. They have previously... view more... (2000-12-13)

Common beta-agonist inhalers more than double death rate in COPD patients, Cornell and Stanford scientists assert
A new analysis that compares two common inhalers for patients suffering from chronic obstructive pulmonary disease (COPD) finds that one reduces respiratory-related hospitalizations and respiratory deaths, but the other — which is prescribed in the majority of cases — increases respiratory deaths.   view more (2006-07-10)
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