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Naltrexone is effective for Alaska Natives and other Alaskans living in rural areas Access to treatment for alcohol dependence (AD) in rural and remote areas is limited. view more (2008-05-12)
Calcium supplements may prevent fractures in elderly women who take them regularly Calcium supplements may be an ineffective way of preventing bone fractures among the population of elderly women because of poor long-term compliance with the therapy, but appear to be effective for women who take the supplements regularly. view more (2006-04-25)
HALT study: Black cohosh no better than placebo for hot flashes The results of a federally funded study to examine whether black cohosh is an effective treatment for hot flashes and night sweats - common symptoms of menopause - found that black cohosh was no better than a dummy pill. view more (2006-12-19)
EARLY PROMISE FOR TREATMENT OF PULMONARY HYPERTENSION (pp 1113, 1119) Encouraging results of a randomised trial in this week’s issue of THE LANCET suggest that the drug bosentan could play an important future role in the treatment of pulmonary hypertension. Pulmonary hypertension (raised pressure in the blood vessels supplying the lungs) causes thickening of the right ventricle of the heart and can be... view more... (2001-10-03)
Medication does not appear to offer benefit for certain heart attack patients undergoing PCI Use of the drug pexelizumab immediately before and for 24 hours after stent placement or angioplasty for certain heart attack patients did not have any significant treatment effect compared to placebo, according to a study in the January 3 issue of JAMA. The medication had shown promise in preliminary studies. view more (2007-01-03)
Study sheds light on medication treatment options for bipolar disorder For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine. view more (2007-03-29)
OBESITY DRUG COULD SUSTAIN WEIGHT LOSS (p 2119) Results of a clinical trial published in this week's issue of THE LANCET suggest that the drug sibutramine is effective in sustaining weight loss in obese patients. However, questions remain about the drug's long-term safety. Sibutramine is a tertiary amine, originally developed as a potential antidepressant. It has been shown to induce... view more... (2000-12-21)
Vitamin K does not stem BMD decline in postmenopausal women with osteopenia In a randomized controlled trial called the "Evaluate the Clinical use of vitamin K Supplementation in Postmenopausal Women with Osteopenia" (ECKO) trial, Angela Cheung and colleagues at the University of Toronto found that a high dose daily vitamin K1 supplement did not protect against age-related bone mineral density (BMD) decline. view more (2008-10-14)
Statins Could Reduce Risk Of Cardiovascular Disease The benefit of statins to prevent cardiovascular disease could extend to people receiving therapy for high blood pressure, conclude authors of an international study published in THE LANCET this week.1 Statins (a class of cholesterol-lowering drugs) are well known for their effectiveness in reducing cardiovascular risk. No study, however, has... view more... (2003-03-31)
Acid-reducing medicines may lead to dependency Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals. view more (2009-07-01)
Study suggests anesthetic agent may have rapid antidepressant effects A single intravenous infusion of a drug known as ketamine, which is a general anesthetic agent, may relieve symptoms of depression within two hours and remain effective for up to one week. view more (2006-08-08)
Anti-epileptic Drug Could Be Future Treatment Option For Alcoholism (pp 1666, 1677) Authors of a US study in this week's issue of THE LANCET provide evidence that the anti-epileptic drug topiramate could be an effective future treatment for alcohol dependence. Bankole A Johnson from the University of Texas Health Science Center at San Antonio, USA, and colleagues randomly allocated 150 heavy drinkers (defined as 5 alcoholic... view more... (2003-05-14)
First human tests of antidepressant bupropion as methamphetamine addiction treatment hold promise A new study led by researchers at UCLA's Semel Institute suggests the antidepressant bupropion may help treat methamphetamine addiction. No medications presently are approved for treating methamphetamine addicts. view more (2005-11-29)
Statins benefit for kidney-transplant patients Embargo: 0001 H (London time) Tuesday 3 June 2003. Authors of a study published on THE LANCET'S website today (www.thelancet.com) highlight how statins (cholesterol-lowering drugs) could offer protection against cardiovascular disease for people who have undergone kidney transplantation. Kidney-transplant patients are at an increased risk of... view more... (2003-05-30)
PREOPERATIVE NUTRITIONAL SUPPLEMENT IMPROVES OUTCOME FOR HIGH-RISK PATIENTS UNDERGOING HEART SURGERY (p 696) An immune-enhancing nutritional supplement conventionally used in critical care and cancer surgery could be beneficial for elderly and other high-risk patients requiring cardiac surgery, conclude authors of a study in this week’s issue of THE LANCET. Elderly patients and those with poor ventricular function have increased illness and death... view more... (2001-08-29)
ESC Congress 2004: New study confirms benefits of rimonabant in weight loss, waistcircumference reduction and metabolic risk factor improvement 1st year results of RIO-Europe study presented at the European Society of Cardiology (ESC) 2004 Congress view more (2004-08-29)
UT School of Public Health researchers discover significant efficacy of travelers' diarrhea vaccine Researchers at The University of Texas School of Public Health have found that patients given a travelers' diarrhea vaccine were significantly less likely to suffer from clinically significant diarrhea than those who received placebo, according to a study published in this week's edition of the Lancet. The patch-based vaccine is part of the Phase... view more... (2008-06-12)
Adding simehicone to sodium phosphate bowel preparation benefits colonscopy? Bowel preparation has been reported inadequate in 10%-75% of colonoscopic examinations. view more (2009-07-08)
Citalopram no better than placebo treatment for children with autism spectrum disorders Citalopram, a medication commonly prescribed to children with autism spectrum disorders (ASD), was no more effective than a placebo at reducing repetitive behaviors. view more (2009-06-02)
Positive study results for methylphenidate transdermal system Shire announced at the US Psychiatric and Mental Health Congress in Las Vegas, Nevada, that its investigational methylphenidate transdermal system (MTS) demonstrated statistically significant reductions in the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD). view more (2005-11-14)
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