Plasminogen Current Events | Plasminogen News | 2
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Cord blood cells may widen treatment window for stroke
Researchers at the University of South Florida found that human umbilical cord blood cells administered to rats two days following a stroke greatly curbed the brain's inflammatory response, reducing the size of the stroke and resulting in greatly improved recovery. view more (2005-11-14)
Stroke patients with mild symptoms may still need clot-dissolving drug
Although use of the clot-dissolving drug tissue plasminogen activator (tPA) has revolutionized the treatment of acute stroke patients, many of those who could receive the drug do not because their initial symptoms appear mild or improve soon after they arrive at the hospital. view more (2005-10-07)
New compound reduces stroke damage
A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms. view more (2006-05-16)
Blocking toxic effects could make clot-buster safer
Since the introduction of the life-saving clot-busting drug tPA more than a decade ago, evidence has been accumulating that tPA (tissue-type plasminogen activator) can be a double-edged sword for a brain affected by stroke. view more (2009-01-23)
Plasminogen activator inhibitor type-1 -- a potential link between heart failure and diabetes
Researchers at the University of Vermont Cardiovascular Research Institute, Colchester, Vermont have found that increased expression in the heart of plasminogen activator inhibitor type-1 (PAI-1) is profibrotic. view more (2009-02-24)
Analysis of breast-cancer gene role offers promising target
Researchers at UT Southwestern Medical Center have for the first time described how multiple copies of a gene are responsible for metastases in early-stage breast cancer and poor prognosis for patients. view more (2006-10-31)
Men at increased risk of death from pneumonia compared to women
Men who come to the hospital with pneumonia generally are sicker than women and have a higher risk of dying over the next year, despite aggressive medical care. view more (2008-05-19)
Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers
Researchers at the University of Pennsylvania School of Medicine have shown how Argos, a fruit fly protein, acts as a ¡¥decoy' receptor, binding growth factors that promote the progression of cancer. view more (2008-05-29)
Medication may promote opening of arteries following stroke
A medication known as argatroban, when combined with another drug already used in the treatment of stroke patients, may help restore the flow of blood through blocked arteries. view more (2006-08-15)
Researchers fine-tune clot-busting treatment for bleeding in brain
A multicenter study led by Johns Hopkins doctors has fine-tuned the dosage and timing for administering clot-busting tissue plasminogen activator (tPA) to patients with strokes caused by bleeding within the brain. The treatment, as reported this week at the European Stroke Conference in Nice, France, has been shown to dramatically decrease death... view more... (2008-05-14)
Clot-dissolving agent may be beneficial in treatment of severe frostbite
A preliminary study suggests that a blood clot-dissolving medication that is administered to some patients following a stroke or heart attack may help to reduce the risk of amputation following severe frostbite. view more (2007-06-19)
Preclinical Study Links Gene to Brain Aneurysm Formation
University of Cincinnati (UC) neurovascular researchers have identified a gene that-when suppressed or completely absent-may predispose a person to brain aneurysms. view more (2007-08-08)
Air pollution linked to cardiovascular risk indices in healthy young adults
Researchers in Taiwan have demonstrated for the first time that urban air pollution simultaneously affects key indicators of cardiovascular risk in young adults: inflammation, oxidative stress, coagulation and autonomic dysfunction. view more (2007-08-15)
UT Houston researchers use stroke patient's own stem cells in trial for first time Phase I trial will enroll 10 patients
For the first time in the United States, a stroke patient has been intravenously injected with his own bone marrow stem cells as part of a research trial at The University of Texas Medical School at Houston. view more (2009-04-16)
Intravenous delivery of clot-busting drug still best intervention for ischemic stroke
Intravenous delivery of an approved clot-busting drug remains the most beneficial proven intervention for ischemic stroke, according to updated American Heart Association/American Stroke Association guidelines published in Stroke: Journal of the American Heart Association. view more (2007-04-16)
Drug-ultrasound combination increases reopening of blocked arteries after stroke
Standard clot-busting medication combined with low-energy ultrasound appears to reopen clogged arteries in stroke patients better than medication alone. view more (2006-02-16)
One Disease, Two Effects: Stroke
Congress is expected to take up legislation this summer aimed at improving the nation's healthcare system. Whatever the shape of the final bill, it will have at least some impact on one of the three leading causes of death in the U.S.: stroke. view more (2009-07-16)
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