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POSSIBLE EXPLANATION FOR FEVER AFTER PLATELET TRANSFUSION
A preliminary study published in this week's issue of THE LANCET suggests a possible explanation for the biological process responsible for inducing fever and related symptoms after the transfusion of blood platelets. Millions of platelet transfusions are done every year, and febrile (fever) reactions occur in around a third of cases. Most... view more... (2001-06-20)

Major discovery raises prospect of better patient care by improving platelet life span
The research team led by Drs Benjamin Kile and David Huang has discovered that platelet life span is controlled by two key molecules. The discovery raises the prospect of developing a new drug to prolong the life span of platelets stored in blood banks, effectively increasing the availability of this life-saving blood product.   view more (2007-03-23)

Positive clinical trial results of investigational thrombocytopenia agent
AKR-501 is a promising member of a new class of agents called, "TPO receptor agonists" that is now in Phase II clinical development.   view more (2006-12-13)

Potential risk identified in transfusions of platelets before bone marrow transplant
Research on blood transfusions points to a potential risk of transfusing donated platelets, especially to patients with bone marrow failure syndromes who are subsequently candidates for bone marrow transplantation.   view more (2009-08-11)

Risk of death may be higher with drug commonly used during cardiac surgery
The risks of death are probably higher with aprotinin, a drug commonly used to control blood loss and transfusions during cardiac surgery.   view more (2008-12-03)

Eltrombopag Effective for Hepatitis C Patients With Low Blood-Platelet Counts
For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease.   view more (2008-01-02)

Study Finds Half of Patients Undergoing Cerebrovascular Stent Placement Respond Poorly to the Antiplatelet Drug Clopidogrel (Plavix)
A study by researchers at Rush University Medical Center, published in the February issue of the American Journal of Neuroradiology, finds that half of patients undergoing cerebrovascular stent placement did not respond well to clopidogrel. Clopidogrel (Plavix) and aspirin are medications routinely prescribed for 1-3 months following... view more... (2008-02-06)

Gel derived from a patient's own blood may help promote wound healing
A preliminary study suggests that topical application of a gel made from platelets in healthy individuals' own blood may help wounds heal more quickly and completely.   view more (2007-05-22)

New study finds antibiotic vancomycin may trigger dangerously low platelet count
The antibiotic vancomycin often used in intensive care units is considered the drug of choice for the treatment of staphylococci (staph) infections that are resistant to most other antibiotics.   view more (2007-03-01)

Novel therapeutic approaches may improve patient outcomes in several platelet disorders
Four studies that highlight significant advances in treatment and survival outcomes for patients with various forms of thrombocytopenia, a group of bleeding disorders characterized by a low number of platelets in the blood.   view more (2008-12-08)

Blood transfusions should be used in moderation for acute coronary syndrome
In a study of more than 44,000 patients being treated for a possible heart attack, cardiologists at the Duke Clinical Research Institute found that while transfusions were associated with a benefit in some patients, they were associated with harm in others.   view more (2006-11-16)

Naturally-occuring protein may be effective in limiting heart attack injury and restoring function
Medical College of Wisconsin researchers in Milwaukee have shown for the first time that thrombopoietin (TPO), a naturally occurring protein being developed as a pharmaceutical to increase platelet count in cancer patients during chemotherapy, can also protect the heart against injury during a heart attack.   view more (2008-05-07)

Innovative Gel Reduces Post-Operative Pain Following Endoscopic Sinus Surgery
A gel made from a patient's own blood reduces pain and may improve wound healing following endoscopic sinus surgery according to researchers at Rush University Medical Center.   view more (2005-10-14)

Decline in blood platelet count associated with increased risk of HIV-related dementia
HIV patients with declining platelet counts appear to be at increased risk for HIV-associated dementia, according to a report in the September issue of Archives of Neurology, one of the JAMA/Archives journals.   view more (2007-09-11)

Drug boosts platelets in hepatitis C patients
It's not a cure, but this may be some of the best news patients infected with the hepatitis C virus (HCV) have heard in a long time: A new drug, eltrombopag, appears to be effective in boosting low platelet counts, one of the major reasons why patients can't endure antiviral treatments.   view more (2007-11-29)

Bioreactors might solve blood-platelet supply problems
It might be possible to grow human blood platelets in the laboratory for transfusion, according to a new study at The Ohio State University Medical Center.   view more (2008-12-23)

Cancer research summaries
Individuals who receive blood transfusions from donors with undiagnosed cancers are at no higher risk of developing malignant disease than people who receive blood from donors without cancer, according to the results of a retrospective study published in The Lancet last month.   view more (2007-07-23)

Blood transfusion study: Less is more
A new study suggests that blood transfusions for hospitalized cardiac patients should be a last resort because they double the risk of infection and increase by four times the risk of death.   view more (2009-08-06)

Hopkins study shows low-dose aspirin suppresses clumping of blood platelets in both sexes
A once-daily pill of low-dose aspirin helps lower the potential for clot-forming blood cells-in both men and women-to stick together in narrow blood vessels, a study from Johns Hopkins shows.   view more (2006-03-22)

Red blood cell transfusions under scrutiny
Bristol scientists have found that red blood cell transfusions given to people having heart surgery could increase the risk of heart attack or stroke.   view more (2007-11-27)
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