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Researchers use poliovirus to destroy neuroblastoma tumors in mice
The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma. view more (2007-03-16)
Polio Vaccination Strategies Assessed as Eradication Nears
Polio is on track to become only the second disease ever eradicated. In two studies in the Dec. 15 issue of The Journal of Infectious Diseases, now available online, scientists are working to ensure that once it is gone, it stays gone. view more (2005-12-20)
No link between multiple childhood vaccinations and hospitalization for nontargeted diseases
New research does not support a belief that children receiving multiple vaccines increase their risk of hospitalization for a nontargeted infectious disease, according to a study in the August 10 issue of JAMA. view more (2005-08-10)
Polio outbreak from oral vaccine identified - and controlled - in China
A 2004 outbreak of polio in China traced back to live attenuated oral polio vaccine (OPV), which is widely used in global eradication efforts, highlights the small but significant risk to eradication posed by the use of OPV at suboptimal rates of coverage. view more (2006-08-16)
Discovery may help defang viruses
Researchers may be able to tinker with a single amino acid of an enzyme that helps viruses multiply to render them harmless, according to molecular biologists who say the discovery could pave the way for a fast and cheap method of making vaccines. view more (2007-08-29)
Biologists spy close-up view of poliovirus linked to host cell receptor
Researchers from Purdue and Stony Brook universities have determined the precise atomic-scale structure of the poliovirus attached to key receptor molecules in human host cells and also have taken a vital snapshot of processes leading to infection. view more (2008-12-09)
New analysis says eradicating polio a better option than extended control of the disease
Concerns about the high perceived costs of eradicating the relatively low number of polio cases worldwide have led to recent suggestions that it is time to shift from a goal of eradication to control—abandoning eradication and allowing wild poliovirus to continue to circulate, which proponents of control believe can sustain the low number of... view more... (2007-04-12)
Science study explains polio's tenacious grip in India
New research helps explain polio's persistence in India despite massive immunization efforts and offers hope for the campaign to stamp out the virus once and for all. view more (2006-11-17)
Molecular Anatomy of Influenza Virus Detailed
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health in Bethesda, Md., and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza. view more (2007-01-02)
Combination vaccines okay for infants, study shows
A University of Rochester study brings relief to new parents who, while navigating a jam-packed childhood vaccine schedule, can expect to soothe their newborn through as many as 15 "pokes" by his or her six-month checkup. view more (2007-10-04)
Number of cases of most vaccine-preventable diseases in US at all-time low
A comparison of illness and death rates for 13 vaccine-preventable diseases in the U.S., before and after use of the vaccine, indicates there have been significant decreases in the number of cases, hospitalizations and deaths for each of the diseases examined. view more (2007-11-14)
$1.5 billion needed to ensure 12-month stockpile of pediatric vaccines
A six-month stockpile of recommended pediatric vaccines would cost $1 billion and could cover more than 90 percent of U.S. children during a six-month interruption in production, say researchers at two Illinois universities. view more (2006-04-19)
Data shows use of a combination vaccine increased on-time immunization rates in infants
Results from a retrospective observational study of data among members of a managed care health plan in Utah showed that infants who received a combination vaccine had significantly higher rates of receiving all of their vaccinations on-time in the first two years of life compared to infants given separate component vaccines. view more (2006-04-10)
Researchers Examine Evolution of Genes that Trigger the Body's Immune Response to Viral Infection
Virginia Commonwealth University Institute of Molecular Medicine researchers have traced the evolutionary origin of two genes that serve as primary cellular sensors of infection with RNA viruses, such as influenza, poliovirus, West Nile virus, and HIV, which may ultimately provide researchers with insight into a possible new pathway for the... view more... (2008-10-22)
Eliminating polio requires global, coordinated effort -- Health Affairs article highlights risks, rewards of eradication
Eliminating polio everywhere will require global cooperation on several fronts, including lowering the cost for poor countries to vaccinate with inactivated polio vaccine (IPV), says a leading global health researcher in the July/August Health Affairs thematic issue on global health. view more (2009-07-14)
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