Polymerase Current Events | Polymerase News | 3
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RNA enzyme structure offers a glimpse into the origins of life
Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or "ribozyme," that carries out a fundamental reaction required to make new RNA molecules. view more (2007-03-16)
A better way to copy DNA
Scientists have developed a new method for DNA amplification that could replace the polymerase chain reaction (PCR), a technique that is invaluable for both medical diagnostics and basic research but which is confined to the laboratory. In the August issue of EMBO reports, Huimin Kong and colleagues at New England Biolabs (Beverly, MA, USA)... view more... (2004-07-14)
Toward a faster prenatal test for Down syndrome
Scientists in California are reporting an advance toward rapid testing for pre-natal detection of Down syndrome and other birth defects that involve an abnormal number of chromosomes. view more (2007-09-19)
Novel marker of colon cancer
Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide. view more (2008-10-24)
Scientists Discover Role of Enzyme in DNA Repair
Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA. NIAMS and NCI are part... view more... (2007-06-28)
Tribble 3 can induce non-alcoholic fatty liver disease?
Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. view more (2009-06-11)
Caltech biologists find optimistic worms are ready for rapid recovery
For the tiny soil-dwelling nematode worm Caenorhabditis elegans, life is usually a situation of feast or famine. Researchers at the California Institute of Technology (Caltech) have found that this worm has evolved a surprisingly optimistic genetic strategy to cope with these disparate conditions--one that could eventually point the way to new... view more... (2009-03-10)
Geneticists aim to develop test to identify learning disability
Clinical geneticist and principal investigator Dr David FitzPatrick explains: "In approximately 10% of CGMH cases, the condition will be caused by a chromosomal abnormality such as a chromosome 21 problem as in Down's Syndrome. Recent studies have suggested that a further 6% of cases may be caused by tiny sub-microscopic abnormalities at the ends... view more... (2000-01-20)
Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters. view more (2007-07-27)
Labs on a chip
The American bio-technology company, WaferGen, is planning to produce three micro laboratories on three different sensor chips, which were developed in Delft. To this end the company will acquire licences to for the patented design. The contracts will be signed by representatives of WaferGen and by Ir. G.J. van Luijk (chairman of the TU Delft... view more... (2004-06-03)
A better test to detect DNA for diagnosing diease, investigating crimes
Researchers in Singapore are reporting development of a new electronic sensor that shows promise as a faster, less expensive, and more practical alternative than tests now used to detect DNA. view more (2009-08-27)
Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. view more (2005-09-30)
CSHL scientists discover new way in which ubiquitin modifies transcriptional machinery to regulate gene activity
During gene transcription - the process inside the nucleus of cells by which DNA, the genetic material, is copied into RNA - a large, ever-changing multiprotein complex is enlisted to assist the DNA-copying enzyme in its challenging job. view more (2008-12-19)
Faster, more cost-effective DNA test for crime scenes, disease diagnosis
Scientists in Japan are reporting development of a faster, less expensive version of the fabled polymerase chain reaction (PCR) a DNA test widely used in criminal investigations, disease diagnosis, biological research and other applications. view more (2009-07-09)
GEN reports on enhancing the applications of qPCR
Quantitative polymerase chain reaction (qPCR) technology is experiencing a surge of interest and rapid expansion as a result of advances such as instrumentation that pushes capacity to 1,536 wells and optimization-free multiplexing. view more (2009-11-19)
DNA test shows promise for identifying patients with colorectal cancer (p 1283)
Testing for DNA changes in stools might provide a new, accurate, and less invasive way to screen patients for colorectal cancer, conclude the authors of a research letter in this week's issue of THE LANCET. Colorectal cancer is one of the most common cancers in the industrialised world, and early detection might help to reduce the risk of death... view more... (2004-04-14)
Issue 1 of the new journal 'Molecular BioSystems' launched
Celebrations are underway at the Royal Society of Chemistry (RSC), where the first issue of the new chemical biology journal Molecular BioSystems has just been published. The electronic issue is freely available at www.molecularbiosystems.org. The new journal has particular relevance to the -omic sciences, systems biology and molecular medicine... view more... (2005-05-19)
ANALYTICA 2004: The 5 Minute PCR
At Analytica 2004, the Institut für Mikrotechnik Mainz GmbH (IMM) presents the prototype of its modular kit for a "chip-based lab". Thanks to the special microfluidic system and a miniaturized tempering unit, the modular construction system makes it possible to realize reproduceable polymerase chain reactions in less than five... view more... (2004-05-07)
Species detectives track unseen evolution
New species are evading detection using a foolproof disguise - their own unchanged appearance. Research published in the online open access journal, BMC Evolutionary Biology, suggests that the phenomenon of different animal species not being visually distinct despite other significant genetic differences is widespread in the animal kingdom. view more (2007-07-19)
A potential targets for the prevention or treatment of esophageal carcinoma
Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR. view more (2008-10-29)
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