Polymerase Current Events | Polymerase News | 4
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RNA interference toward MMP-2 may be an effective therapeutic strategy for cancer The invasion or metastasis of pancreatic cancer has been known to be a complex process involving many molecular mechanisms, of which proteolytic degradation of extracellular matrix (ECM) exerted by matrix metalloproteinases (MMPs) was considered to be an essential step. view more (2009-03-09)
Hepatitis B drug can compromise HIV treatment Treating hepatitis B patients with the drug entecavir can cause those who are also infected with HIV to become resistant to two of the most important drugs in the anti-HIV arsenal. view more (2007-06-21)
Who found some new mechanisms of HBV virulence? This dreadful HBV is small in size. The genome of this virus is a partial double stranded circle. When made fully double stranded, this genome carries about 3000 base pairs, compared to 200 kilo base pairs of the genome of the smallpox virus. view more (2008-02-25)
How to select anti-hepatitis B virus agents for drug-resistance patients? HBV infection may lead to acute liver disease, chronic active hepatitis, liver cirrhosis, and hepatocellular carcinoma. Over 350 million people worldwide are estimated to be infected chronically by HBV and are therefore at risk of liver failure, cirrhosis, or hepatocellular carcinoma. view more (2008-09-25)
How purple corn and RNA break genetic laws A newly cloned gene in corn will help explain how unusual interactions between a parent's genes can have lasting effects in future generations. The finding has implications for breeding better crop plants and unraveling complex genetic diseases. view more (2006-07-20)
International Surveillance System Suggests 2002 Gastroenteritis Outbreaks Arose From New Variant Norovirus (Pp 671, 682) The increase in severe outbreaks of gastroenteritis in 2002-including the notorious outbreaks on US cruise ships-were probably a result of a new variant of norovirus, conclude authors of a study in this week's issue of THE LANCET. Ben Lopman from the UK Health Protection Agency and European colleagues analysed data collected through a... view more... (2004-02-25)
Study first to show potential of light-activated gene therapy for knee injuries An early study has demonstrated for the first time that laser light can target gene therapy right up to the edge of damaged cartilage, while leaving nearby healthy tissue untouched. view more (2006-04-25)
Test developed at UQ diagnosed Australia's first swine flu victim When the first cases of H1N1 Influenza (swine flu) were reported in Mexico in April, UQ researchers got to work developing a test to diagnose the virus. view more (2009-09-04)
Novel Coronavirus Confirmed As Causative Agent Of SARS Leading scientists worldwide investigating the cause of Severe Acute Respiratory Syndrome (SARS) confirm that a novel coronavirus is the primary cause of the disease. The study is published on THE LANCET's website (www.thelancet.com) at 0001 H Tuesday 22 July UK time. SARS was first reported in China in November 2002, with over 8300 cases and 812... view more... (2003-07-18)
Genome communication In the late 19th century Gregor Mendel used peas to show that one copy of a gene (allele) is inherited from the mother and one from the father. view more (2008-06-30)
Bid To Aid Diagnosis Of Infections In Joint Replacement Surgery A team of scientists and doctors at the University of Edinburgh are using new laboratory techniques which will lead to improved treatment for patients experiencing problems with joint replacement. The multi-disciplinary team will try to establish if using molecular techniques can set a 'gold standard' to allow doctors to know before surgery is... view more... (2002-04-24)
Core needle biopsy gives an accurate picture of gene expression in whole tumor The gene expression profile detected in the core needle biopsy of a breast tumour is representative of gene expression in the whole tumour. view more (2006-08-21)
Geneticists tell ostrich farmers the secrets of sex Research published in the online journal, BMC Biotechnology reports on a new, large-scale technique for distinguishing between male and female ostrich chicks using DNA extracted from feathers. This new technique will remove the need for invasive procedures currently in use to sex-type ostriches and allow breeders to discover the sex of their... view more... (2002-10-16)
SARS Reviewed (p 1730) Authors from WHO describe the emergence of severe acute respiratory syndrome (SARS) in a Public Health article in this week's issue of THE LANCET. SARS is a new disease in human beings, first recognised in late February, 2003, in Hanoi, Vietnam. The severity of the disease, combined with its rapid spread along international air-travel routes,... view more... (2003-05-14)
Cytomegalovirus infection still associated with poor HIV/AIDS prognosis (p 2101, 2116) Results of a UK study in this week's issue of THE LANCET highlight how the treatment of cytomegalovirus infection remains a priority in order to improve the prognosis for people with HIV-1 infection, including people already receiving antiretroviral therapy. The advent of highly active antiretroviral therapy (HAART) at the end of the 20th century... view more... (2004-06-23)
Safer Method for Large-Scale Malaria Screening Developed Researchers at the Johns Hopkins Bloomberg School of Public Health's Malaria Research Institute have developed a new test for detecting the malaria parasite in human urine and saliva. view more (2006-11-21)
PET Scans Could Provide Insight Into HIV-1 Progression (pp 945, 959) An article and a research letter in this week's issue of THE LANCET provide preliminary data suggesting that positron emission tomography (PET) scans could identify the effect of HIV-1 infection on the body's lymphatic system. Authors of the studies suggest that activation of specific lymph nodes could determine the stage of HIV-1 infection, with... view more... (2003-09-17)
Schizophrenia and bipolar disorder could have similar genetic causes (pp 758, 798) Issue 6 September 2003 Embargoed 0001 h (London time) 5 September 2003. Authors of a study in this week's issue of THE LANCET provide strong evidence that schizophrenia and bipolar disorder have a similar genetic cause arising from reduced expression of genes responsible for myelin development of the central nervous system. Schizophrenia and... view more... (2003-09-03)
Proteasome inhibition affects epigenetic mechanisms Alcohol consumption causes alteration in several cellular mechanisms, and leads to inflammation, apoptosis, immunoresponse defect, and fibrosis. view more (2009-02-19)
Little known DNA repair enzyme may be a tumor suppressor gene The DNA in our cells is constantly being bombarded by environmental, chemical and cellular insults. Fortunately, our cells contain many enzymes devoted strictly to detecting and repairing any damage caused by these insults. view more (2006-01-04)
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