Postmenopausal Current Events | Postmenopausal News | 6
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Serendipity versus planning-cancer drugs of the future?
Delegates at the European Breast Cancer Conference (EBCC-5) were given two examples of promising new drugs to watch in the future-raloxifene and lapatinib. view more (2006-03-27)
Drug developed at UC Davis may prevent breast cancer, treat post-menopausal vaginal atrophy
A tamoxifen-like drug developed by UC Davis and Finnish researchers, now in clinical testing as a treatment for vaginal atrophy, may also help to prevent breast cancer, two preliminary studies suggest. view more (2005-11-03)
Cancer risk slightly higher for women in discontinued hormone treatment trial
A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the intervention was stopped, compared to participants in the... view more... (2008-03-05)
Postmenopausal women benefit from endurance training as much as younger women
Marilyn Graham was 56 when she signed up for a grueling hour of cycling each morning for 12 weeks, occasionally decked out in a mask, a heart monitor and a bag of intravenous fluid and subjected to needle pricks to obtain blood samples. view more (2009-09-21)
Effect of hormone therapy on risk of heart disease may vary by age and years since menopause
Secondary analyses of findings from the Womenˇ¦s Health Initiative (WHI) suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to hormone therapy than women farther from menopause. view more (2007-04-04)
Pituitary hormone implicated in bone loss after menopause
New evidence in the April 21, 2006 Cell challenges the long-standing notion that declining estrogen levels alone lead to osteoporosis after women go through menopause. view more (2006-04-21)
Malfunctioning kidneys may raise risk of sudden death in women
Women whose kidneys are poor at filtering impurities from the blood are at heightened risk of sudden cardiac death, according to a report published in Hypertension: Journal of the American Heart Association. view more (2008-04-08)
Exemestane beats tamoxifen in first phase III head to head trial in advanced breast cancer
Hamburg, Germany: The first results from the world's only phase III trial to compare tamoxifen with the newer hormone treatment exemestane in advanced breast cancer shows that exemestane is safe, superior and lengthens progression-free survival. The median progression-free survival for patients taking exemestane was 10.9 months compared with 6.7... view more... (2004-03-16)
Selective Estrogen Receptor Modulators Offer A Safer Alternative than Hormone Replacement Therapy to Postmenopausal Women
Selective Estrogen Receptor Modulators (SERMs) Eliminate Risk of Breast Cancer Associated with Hormone Replacement Therapy But Preserve Many Health Benefits of Estrogen Tissue-Specific Estrogenic and Antiestrogenic Activity of SERMs Provide Opportunities for Individualized Treatment of... view more... (2002-12-12)
Study finds link between hot flashes and lower bone density in women
esearchers and colleagues analyzed data for 2,213 women between the ages of 42 and 52 who participated in the bone sub-study of the Study of Women's Health Across the Nation to determine whether women with vasomotor symptoms (VMS) - which include hot flashes and night sweats - had lower bone mineral density. view more (2009-05-06)
Women with breast cancer do not get potentially life-saving information, survey reveals
New published data from a large pan-European survey indicate that the majority of postmenopausal women with early breast cancer taking post-surgical endocrine therapy are not involved in making key decisions about their treatment, nor are they given sufficient information to make informed treatment choices that could affect their long-term outcome. view more (2007-05-24)
Breast Cancer, Prognostic Factors, Mortality, Recurrence
Tumor Grade, Age at Diagnosis of First Tumor, and Duration Without Cancer Predict the Risk of Death After a Local Recurrence of Breast Cancer view more (2002-05-16)
Groundbreaking research highlights myriad health benefits of flavanol-rich cocoa
Research has demonstrated that consumption of naturally occurring compounds in cocoa can lead to a range of circulatory health benefits including the first observed brain and cardiovascular blood flow improvements. view more (2006-07-26)
Studies find no evidence that estrogens in soy increase uterine cancer risk
Studies in monkeys and women suggest that unlike traditional estrogen therapy, a diet high in the natural plant estrogens found in soy does not increase the risk of uterine cancer in postmenopausal women. view more (2005-11-03)
IMS reaction to report on breast cancer incidence in 2003 in US
A special report in the April 19 issue of the New England Journal of Medicine [1] brings initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology and End Result (SEER) registries, showing that the incidence of breast cancer in women in the US fell by 6.7% in 2003, and stayed at the same level in 2004. view more (2007-04-19)
American Cancer Society report finds breast cancer death rate continues to drop
A report from the American Cancer Society finds the breast cancer death rate in the United States continues to drop more than two percent per year, a trend that began in 1990 and is credited to progress in early detection and treatment. view more (2007-09-26)
New Study Finds Adverse Effects Of Estrogen Replacement Therapy (ERT) Are Related To The Dose
Recent clinical trials indicate that estrogen replacement therapy (ERT) may increase the risk of cardiovascular diseases. A new study in mice has examined whether adverse effects of ERT are related to the doses used. view more (2008-04-08)
IMS updated recommendations on postmenopausal hormone therapy
The past decade has seen marked fluctuations in opinions concerning the merits and risks of postmenopausal hormone therapy. view more (2007-05-16)
Media Availability: Low-Fat Dietary Pattern May Lower Risk of Ovarian Cancer -- The WHI Dietary Modification Trial
A diet low in fat could reduce the risk of ovarian cancer in healthy postmenopausal women, according to new results from the Women's Health Initiative (WHI) Dietary Modification Trial. Researchers found that after four years, women who decreased the amount of dietary fat they consumed were 40 percent less likely to develop ovarian cancer than... view more... (2007-10-10)
Merck's odanacatib increased BMD over 2 years at key fracture sites in Phase IIB study
Two-year data from a Phase IIB study of odanacatib (formerly MK-0822), an investigational, selective cathepsin-K inhibitor in development for the treatment of osteoporosis by Merck & Co., Inc., demonstrated dose- dependent increases in bone mineral density (BMD) at the total hip, lumbar spine and femoral neck fracture sites and decreased... view more... (2008-09-17)
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