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DASNR researchers make breakthrough against poxviruses
Smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against which the human body's immune system is ineffective in its defense.   view more (2009-01-26)

Poxvirus' ability to hide from the immune system may aid vaccine design
The cowpox virus, a much milder cousin of the deadly smallpox virus, can keep infected host cells from warning the immune system that they have been compromised, researchers at Washington University School of Medicine in St. Louis have found.   view more (2007-11-16)

Poxvirus Potency Uncovered in New Atomic Map
Scientists at the University of Alabama at Birmingham (UAB) and Saint Louis University used X-ray crystallography to uncover new details about the infectious potency of poxviruses, furthering the understanding of how viral infections can subvert the body's immune system.   view more (2008-02-04)

Novel virus entry mechanism could lead to new drugs against poxviruses
Research published in the Proceedings of the National Academy of Sciences on 11 April describes how the Imperial College London team discovered the mechanism allowing Vaccinia virus to shed its outer lipid membrane and enter cells. The mechanism is unique in virology and paves the way for development of new antiviral drugs.   view more (2006-04-12)

Ugandan monkeys harbor evidence of infection with unknown poxvirus
Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox.   view more (2008-04-23)

How to design a cancer-killing virus
One new way to treat individuals with cancer that is being developed is the use of viruses that infect and kill cancer cells while leaving normal cells unharmed.   view more (2007-10-26)

Penn researchers determine structure of smallpox virus protein bound to DNA
Researchers at the University of Pennsylvania School of Medicine have determined the structure of an important smallpox virus enzyme and how it binds to DNA.   view more (2006-08-07)

New molecular clock from LLNL and CDC indicates smallpox evolved earlier than believed
Smallpox is older than thought, according to results of a new technique reported in the Sept. 24 issue of the Proceedings of the National Academy of Sciences by researchers from Lawrence Livermore National Laboratory and the Centers for Disease Control (CDC).   view more (2007-09-26)

Prostate cancer vaccines more effective with hormone therapy
Among patients with castration-resistant prostate cancer, the addition of hormone therapy following vaccine treatment improved overall survival compared with either treatment alone or when the vaccine followed hormone treatment, according to recent data published in the July 15 Clinical Cancer Research, a journal of the American Association for... view more... (2008-07-10)

"EuroVacc 02" HIV Vaccine trial begins
The European Vaccine Effort against HIV/AIDS, today announced that a phase I clinical trial of novel investigational vaccines comprising DNA-HIV-C and NYVAC-HIV-C for the prevention of HIV infection has started in Lausanne and London in February 2005. These vaccines are based on HIV subtype C, which is prevalent in China, India and sub-Saharan... view more... (2005-02-16)

Protein finding could lead to treatment for inflammatory diseases
A protein that undesirably shields a skin poxvirus from the immune system may become the key ingredient in a new topical treatment for inflammatory diseases.   view more (2006-01-12)

Press release from Nature and the Nature Research Journals
This Press Release contains: ·Summaries of newsworthy papers: NANOSCALE ARMS CONTROL - Nature Materials STEPMOTHER OF PEARL - Nature Materials COMBINATION VACCINE DELIVERS DOUBLE BLOW - Nature Medicine STEM CELL ENGRAFTMENT SUCCESS DOES NOT ENSURE LONG-TERM SURVIVAL - Nature Immunology Mention of papers to be published at the same time with the... view more... (2003-05-27)

Scientists identify genetic cause of previously undefined primary immune deficiency disease
Researchers at the National Institutes of Health have identified a genetic mutation that accounts for a perplexing condition found in people with an inherited immunodeficiency.   view more (2009-09-25)

Researchers develop new testing methods for potential monkeypox or smallpox outbreak
Researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University have developed new diagnostic methods to better detect future monkeypox or smallpox outbreaks.   view more (2005-08-09)
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