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Unfolded proteins may protect cells from dying
When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually serves a protective role; rather than a sign that the cell has given up, it may be a mechanism by which the cells cope with adversity. view more (2006-12-27)
Wheat gene may boost foods' nutrient content
Researchers at the University of California, Davis; the U.S. Department of Agriculture; and the University of Haifa in Israel have cloned a gene from wild wheat that increases the protein, zinc and iron content in the grain, potentially offering a solution to nutritional deficiencies affecting hundreds of millions of children around the world. view more (2006-11-27)
Same gene mutation in urinary protein responsible for two different types of kidney disease
The same gene mutation in a urinary protein causes two different types of kidney disease, research in the Journal of Medical Genetics shows. view more (2002-12-06)
Ume'å scientist presents discoveries about natural immunity in Science
A team including scientists at UCMP (Ume'å Center for Molecular Pathogenesis), a research unit at Ume'å University, shows in last week's issue of the journal Science that the protein PGRP-LC plays a crucial role in so-called innate immunity. Professor Dan Hultmark, post-doctoral fellow Svenja Stöven, and doctoral candidate Thomas... view more... (2002-03-04)
McMaster University researchers discover zip codes for protein
McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD). view more (2007-01-30)
Scientists locate disease switches
A team of scientists from the University of Copenhagen and the Max Planck Institute in Germany, using groundbreaking technology, has identified no less than 3,600 molecular switches in the human body. view more (2009-07-17)
ESC Congress 2003: Prothrombotic mutations are associated with increased cardiovascular events in postmenopausal women receiving hormone replacement therapy
IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology Recent studies have suggested that hormone replacement therapy may be associated with an increased... view more... (2003-09-01)
Proteasome activator enhances survival of Huntington's disease neuronal model cells
To function, each living cell needs both to build new and to degrade old or damaged proteins. To accomplish that, a number of intracellular systems work in concert to keep the cell healthy and from clogging up with damaged proteins. view more (2007-02-28)
US Patent Granted for Method to Detect Protein Translocations in Cells - Redistribution™
BioImage A/S today announced that it had been granted US 6,518,021, a patent covering the detection of protein translocation in cells using luminophores, such as green fluorescent protein (GFP), fused to the target protein. Redistribution™ - the name coined by the company to describe its technology that monitors protein translocation in real... view more... (2003-03-03)
Cereal and milk is the new sports supplement
Exercise physiologist Lynne Kammer, from The University of Texas at Austin, led a group of researchers who investigated the post-exercise physiological effects of the foods. view more (2009-05-14)
New antifreeze protein may allow longer storage of transplant organs
A new antifreeze protein discovered in tiny snow fleas by Queen's University researchers may lengthen the shelf life of human organs for transplantation. view more (2005-10-24)
Hybrigenics Launches Pharma Industry’s First Proteomics Database For Hiv Drug Development Proprietary Hiv Bioinformatics Platform At Keystone Symposia Meeting
Paris, France - Hybrigenics, the functional proteomics company, announces the launch of the world’s most comprehensive combined protein-protein interactions “map” between the human immunodeficiency virus (HIV) and its host cell in humans. This represents the first time that a fully integrated HIV-Human protein pathway has been... view more... (2001-03-29)
Enzyme fights mutated protein in inherited Parkinson's disease
An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson's disease, researchers at UT Southwestern Medical Center have found. view more (2009-06-29)
A new hope for heavy metal contaminated soils
In the 1980s scientists began laboratory studies on metal hyperaccumulator plants, i.e. plants which accumulate exceptionally high concentrations of heavy metals in their above-ground biomass. This coincided with the recognition that a number of serious human diseases are the result of disruptions in metal homeostasis, for example Menke's disease,... view more... (2003-12-05)
Sugar coupled to protein causes kidneys to save water
Several new mechanisms that are important for the production and transport of water channels to the cell surface of kidneys have been identified by a Dutch researcher. The water channels ensure that water in the body is reused. If these fail to work properly, you urinate too much and dehydrate. The research was a collaborative project between the... view more... (2003-10-10)
Targeting the protein AEG1 impairs human liver cancer growth in mice
Hepatocellular carcinoma (HCC) is a highly aggressive form of liver cancer and one of the 5 most common cancers worldwide. Devanand Sarkar and colleagues, at Virginia Commonwealth University School of Medicine, Richmond, have now identified a gene that is expressed at high levels in human HCC tumor samples and generates a protein important for HCC... view more... (2009-02-17)
Is one diet as good as another? U of I study says no and tells you why
Any diet will do? Not if you want to lose fat instead of muscle. Not if you want to lower your triglyceride levels so you'll be less likely to develop diabetes and heart disease. Not if you want to avoid cravings that tempt you to cheat on your diet. And not if you want to keep the weight off long-term. view more (2009-03-05)
Turning down gene expression promotes nerve cell maintenance
Anyone with a sweet tooth knows that too much of a good thing can lead to negative consequences. The same can be said about the signals that help maintain nerve cells, as demonstrated in a new study of myelin, a protein key to efficient neuronal transmission. view more (2009-02-02)
Dysfunctional protein dynamics behind neurological disease?
Researchers at Lund University, Sweden, have taken a snapshot of proteins changing shape, sticking together and creating structures that are believed to trigger deadly processes in the nervous system. view more (2009-10-14)
News brief: Effects of aspirin and folic acid on inflammation markers for colorectal adenomas
Unexpectedly, inflammation markers do not appear to be involved with the chemopreventative effect of aspirin on colorectal adenomas, according to a brief communication published online October 12 in the Journal of the National Cancer Institute. view more (2009-10-13)
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