Prion Protein Current Events | Prion Protein News | 2
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The CReSA is working on a new strategy to combat spongiforms
Researchers at the Animal Health Research Centre (CReSA) are developing immunotherapeutical strategies against diseases produced by prion, such as Bovine Spongiform Encephalitis. view more (2006-11-01)
Prion disease infectivity causes heart damage in mouse study
Laboratory mice infected with the agent of scrapie—a brain-wasting disease of sheep—show high levels of the scrapie agent in their heart several hundred days after being infected in the brain, indicating that heart infection might be a new aspect of this disease. view more (2006-07-07)
New data on "mad cow" disease
A research team at the University of Navarre has detected the presence of the prion protein in the digestive tract of three animal species: the autochthonous Pyrennean cow, in a primate and in rats. This study is the first to describe the exact location of the "healthy" form of the prion (PrPc), a protein necessary for the development of... view more... (2004-11-16)
Brittle prions are more infectious
Brittleness is often seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a tougher, more menacing pathogen. view more (2006-06-29)
New Diagnostic Test for New Variant Creudzfeldt-Jakob Disease
Date: Thursday 14 January 1999 view more (1999-01-14)
How small molecule can take apart Alzheimer's disease protein fibers
Researchers from the University of Pennsylvania School of Medicine have shown, in unprecedented detail, how a small molecule is able to selectively take apart abnormally folded protein fibers connected to Alzheimer's disease and prion diseases. view more (2008-05-16)
Spatial Molecular Structure of the Bovine Prion Protein Decoded at the ETH Zurich
The healthy prion proteins of humans and bovine cattle are very similar. It therefore appears, that transmission of Mad Cow Disease (BSE) to humans might be rationalized on the level of the molecular structure. This is reported by a research team from the Institute for Molecular Biology and Biophysics of the ETH Zurich (The Swiss Federal Institute... view more... (2000-07-11)
Large-Scale Tonsillectomy Would Quantify UK CJD Prevalence (pp 1196, 1260)
A study in this week's issue of THE LANCET describes how two different types of analysis used in conjunction on samples of tonsil tissue is the 'gold standard' method for confirming clinical variant CJD, and that a large-scale screening programme of tonsil tissue is the only way of identifying the true incidence of vCJD infection. view more (2004-09-29)
Scientists identify prion's infectious secret
Researchers have known for decades that certain neurodegenerative diseases, such as mad cow disease or its human equivalent, Cruetzfeldt-Jakob disease, result from a kind of infectious protein called a prion. view more (2007-05-10)
K-State professor's USDA research shows mad cow disease also caused by genetic mutation
New findings about the causes of mad cow disease show that sometimes it may be genetic. view more (2008-09-12)
Scientific advance establishes ‘proof of principle’ that prion diseases might be prevented using monoclonal antibody technology
UK scientists have made a major scientific advance by establishing proof of principle that the development of prion disease can be prevented in mice using monoclonal antibodies (mAbs). The work lays the foundation for further research to explore the potential of mAbs to treat specific prion diseases such as CJD and vCJD. The work is published... view more... (2003-03-03)
Action needed to prevent spread of vCJD
Urgent action is needed to protect the public from variant Creutzfeldt-Jakob disease (vCJD), a senior member of the Medical Research Council writes in this week's BMJ. Dr Sheila Bird argues that the death of the first probable victim of vCJD from a blood transfusion means that steps must be taken to define the rights and responsibilities of those... view more... (2004-01-17)
Scripps Florida scientists devise accelerated method to determine infectious prion strainsScripps Florida scientists devise accelerated method to determine infectious prion strains
Current tests to identify specific strains of infectious prions, which cause a range of transmissible diseases (such as mad cow) in animals and humans, can take anywhere from six months to a year to yield results - a time-lag that may put human populations at risk. view more (2009-05-29)
Blocking nerve cells delays onset of prion disease
A chemical that specifically blocking parts of the nervous system can delay the onset of scrapie and could lead to new drugs to prevent vCJD and BSE, medical experts heard today (Thursday 10 January 2002) during a joint meeting of the European Societies of Clinical and Veterinary Virology and the Society for General Microbiology at the Royal... view more... (2001-12-21)
Blood transfusion poses CJD risk (pp 411, 417, 422)
Two studies in this week's issue of THE LANCET highlight the public-health implications of blood transfusion as a possible route for infection by the prion protein responsible for variant Creutzfeldt-Jakob disease (vCJD). The death from vCJD of an individual in the UK who had previously received a blood transfusion from a donor who went on to... view more... (2004-02-04)
Commercial BSE testing now a reality in the UK
The announcement today (Jan 16, 2002) by Reading Scientific Services Ltd, that it has been granted UKAS accreditation by the Government Department for Environment, Food and Rural Affairs to conduct commercial BSE testing, is a first for the UK. view more (2002-01-16)
Studies validating performance of Pall prion reduction technology presented at AABB
Prion diseases, such as variant Creutzfeldt-Jakob Disease (vCJD), the human form of Bovine Spongiform Encephalopathy or "mad cow" disease, are of growing concern to blood services worldwide because of the potential for transmission through transfusion from asymptomatic donors. view more (2005-10-18)
Prevention of scrapie by means of selection in animals
To help prevent scrapie in sheep by means of animal selection is the aim of a project, throughout the whole of Spain, by a research group from the Agrarian Production Department of the Public University of Navarre together with other institutions such as the National Institute for Agrarian and Animal Feed Research & Technology (INIA), the... view more... (2003-03-27)
Prevalence of variant CJD agent in Britain remains uncertain
First results from a large tissue survey in Britain of the agent that causes variant Creutzfeldt-Jakob disease (vCJD) are unable so far to establish that the prevalence is lower than that given by previous estimates, concludes a study published on bmj.com today. view more (2009-05-22)
Prion disease agent causes heart damage in mouse study
These findings raise the possibility that heart infection could be a new aspect of prion diseases, including those that affect humans and livestock, and that these diseases could travel through the blood. view more (2006-07-10)
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