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Therapy For Mice With Prion Disease Could Offer Benefit To Human Beings With CJD
Authors of a fast-track research letter in this week's issue of THE LANCET describe a therapeutic treatment which increased the survival time for mice with prion disease. These results could represent a new approach to treating CJD in human beings. The lack of an immune response to prions-the infectious proteins that cause scrapie, bovine... view more... (2002-07-17)
Cell cultures can sort out Creutzfeldt-Jacob Disease (CJD) and scrapie infectious agents
Research in Japan and at Yale University School of Medicine shows that infection with a weak strain of Creutzfeldt-Jacob Disease (CJD) prevents infection by more virulent strains and that the protection requires persistent replication by the infectious agent, but not misfolded prions. view more (2005-10-21)
Should dentists worry about vCJD transmission?
Existing guidelines on treating patients with diseases such as Creutzfelt-Jakob disease (CJD) do not cover dental health in any detail. Writing in the April Journal of the Royal Society of Medicine, Professor Stephen Porter of the Eastman Dental Institute at the University of London suggests "important modifications" to the current infection... view more... (2002-04-02)
Mad cow protein aids creation of brain cells
Few conditions are more detrimental to human brains than the one popularly referred to as mad cow disease. view more (2006-02-14)
Scripps research study reveals structural dynamics of single prion molecules
New techniques paint clearer picture of amyloid formation associated with protein-based inheritance and neurodegenerative diseases such as mad cow, Alzheimer's. view more (2007-02-13)
Redefining what it means to be a prion
Whitehead Institute researchers have quintupled the number of identifiable prion proteins in yeast and have further clarified the role prions play in the inheritance of both beneficial and detrimental traits. view more (2009-04-03)
Mad-cow culprit maintains stem cells
What do mad cow disease and stem cell research have in common? Whitehead Institute scientists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopathy (mad cow disease) is also important for helping certain adult stem cells maintain themselves. view more (2006-01-31)
Can senile amyloidosis spread from mother to offspring?
Researchers have demonstrated spread of senile amyloidosis from affected mice to their nursing offspring. view more (2006-05-01)
NIAID scientists characterize the most infectious prion protein particles
A new study of prions-apparently malformed proteins that initiate deadly brain diseases such as Creutzfeldt-Jakob disease in humans-has yielded surprising information about how the size of prions relates to their infectivity. view more (2005-09-08)
Soil-bound prions that cause CWD remain infectious
Scientists have confirmed that prions, the mysterious proteins thought to cause chronic wasting disease (CWD) in deer, latch on tightly to certain minerals in soil and remain infectious. view more (2006-04-14)
Self-regulating molecular 'transformers' control intracellular protein delivery
Scientists from the California Institute of Technology (Caltech) have uncovered the Transformer like properties of molecules responsible for carrying and depositing proteins to their correct locations within cells. view more (2009-02-11)
Mad cow proteins successfully detected in blood
Researchers at the University of Texas Medical Branch at Galveston (UTMB) have found a way to detect in blood the malformed proteins that cause "mad cow disease," the first time such "prions" have been detected biochemically in blood. view more (2005-08-29)
Evidence for scrapie prions in muscle tissue of animals prior to onset of clinical disease
Scientists from Berlin and Göttingen (Germany) discover, how scrapie agent spreads to muscles The infectious agent causing transmissible spongiform encephalopathies (TSEs) or prion diseases such as scrapie can be detected in muscle tissues before clinical symptoms become visible.The scrapie agent is able to propagate in muscle tissue to which... view more... (2004-05-19)
Novel saw cuts BSE contamination risk
EMBARGOED UNTIL WEDNESDAY 16 OCTOBER 2002 19:00 BST UK CONTACT - Claire Bowles, New Scientist Press Office, London: Tel: +44(0)20 7331 2751 or email claire.bowles@rbi.co.uk MAD COW DISEASE A NOVEL power saw that can strip the spines out of cattle and sheep carcasses should further cut the risk of infecting people with the agent that causes the... view more... (2002-10-16)
History of human cannibalism eats away at researchers
In a new study published by the journal Genome Research, a team of scientists reports that 'mad cow'-like diseases have not been a major force in human history, nor have been cannibalistic rituals that are known to be associated with disease transmission. view more (2006-01-04)
Successful cell engineering may lead to mad cow prevention, say researchers
Researchers at Texas A&M University have successfully "knocked down" the expression of possible disease-causing genes in a cloned goat fetus, perhaps paving the way for breeding disease resistance in other animals, even those genes that might cause bovine spongiform encephalopathy (BSE), commonly known as Mad Cow Disease. view more (2006-03-23)
Changes in urine could lead to BSE test for live animals
Researchers have demonstrated that protein levels in urine samples can indicate both the presence and progress of Bovine Spongiform Encephalopathy (BSE) disease in cattle. view more (2008-09-08)
Emerging Infectious Diseases Of Wildlife - Microbiology Today: November 2003 issue
Wildlife is an important source of diseases that are a risk to the health of man and his domesticated stock. This was very clearly demonstrated earlier this year when the masked palm civet was implicated as a possible wild animal source for the SARS (Severe Acute Respiratory Syndrome) coronavirus. In the November 2003 issue of Microbiology Today... view more... (2003-10-28)
First ever study to investigate impact of chronic wasting disease on humans
Researchers at Binghamton University have a first-ever opportunity to determine if Chronic Wasting Disease (CWD) in deer can be spread to humans who ingest "infected" meat. view more (2005-11-28)
Discoveries should aid research into cause of ALS
Two teams of researchers at Northwestern University have found a novel pathological hallmark of the neurodegenerative disease amyotrophic lateral sclerosis (ALS) at the molecular level. view more (2006-04-26)
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