Prion Protein Current Events | Prion Protein News | 4
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First high-res 3D structures of mammalian HSP90 protein solved
Dr. Dan Gewirth, Hauptman-Woodward senior research scientist, has just solved the structure of the first mammalian GRP94 protein implicated in immune diseases such as sepsis, AIDS and certain cancers. view more (2007-10-15)
Protein involved in mad cow disease
This study, published in Brain Research, is an addition to the work of the Department of Pathological Histology and Anatomy at the University of Navarra regarding the manner in which prions enter the digestive tube of bovine animals, from which organ they enter the central nervous system, causing the mad cow disease or bovine spongiform... view more... (2005-10-19)
IAH Appoints New Head of Prion Disease Research
The Institute for Animal Health is pleased to announce that Dr Jean Manson has been appointed as Head of TSE Research. Dr Manson will take charge of the transmissible spongiform encephalopathy (TSE) research programme, which is located mainly at the Institute's Neuropathogenesis Unit (NPU) in Edinburgh, but also at the Compton Laboratory. Dr... view more... (2003-02-21)
Europe develops new technologies to boost health of livestock
A range of new technologies including genetic modification (GM) and RNA Interference are being deployed to improve the health of farm animals in a series of European and global initiatives. The ground was laid for a European platform to develop new treatments that exploit these technologies at a recent workshop organised by the European Science... view more... (2008-04-09)
Give the foie gras a miss
Another reason not to eat pate de foie gras is discussed by Michael Greger of The Humane Society of the United States, Washington DC in a forthcoming issue of the International Journal of Food Safety, Nutrition and Public Health. view more (2009-02-10)
University to develop new therapeutics for cancer
Dr Roger Barraclough, from the School of Biological Sciences, is working on a new protein which causes some cancer cells to spread around the body. This protein is being developed to assist in improving the management of breast cancer. view more (2006-07-28)
Prion study reveals first direct information about the protein's molecular structure
A collaboration between scientists at Vanderbilt University and the University of California, San Francisco has led to the first direct information about the molecular structure of prions. view more (2009-10-07)
Scientists predict swift end to vCJD epidemic
As few as 40 people over the next 80 years could die from variant Creutzfeldt-Jakob disease (vCJD) as a consequence of eating BSE infected meat. Researchers from Imperial College, London published their new predictions in BMC Infectious Diseases. Previous estimates of the size of the vCJD epidemic have been uncertain, with the estimated upper... view more... (2003-05-19)
Making bacteria make useful proteins
By adapting a single protein on the surface of the bacterium Caulobacter crescentus, researchers at the University of British Columbia have turned it into a protein production factory, making useful proteins that can act as vaccines and drugs. view more (2009-09-08)
Amyloid beta protein gets bum rap
While too much amyloid beta protein in the brain is linked to the development of Alzheimer's disease, not enough of the protein in healthy brains can cause learning problems and forgetfulness, Saint Louis University scientists have found. view more (2009-11-10)
Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
Scientists step up search for BSE test
Research aimed at finding new diagnostic tests for BSE is gathering momentum at the Institute of Grassland and Environmental Research (IGER), where scientists have won a major research contract worth over £500,000 from the Department for Environment, Food and Rural Affairs (DEFRA). `The new contract will help us expand our search for... view more... (2002-04-04)
BSE - A Post Industrial Disease?
Ahead of the Commons debate on BSE due to be held next week, an alternative hypothesis about the origin and behaviour of BSE and vCJD is posed in the latest issue of the SCI publication Chemistry & Industry. Dr David Brown of the University of Cambridge suggests that prion diseases are ‘post-industrial phenomena that will spread in... view more... (2001-02-13)
UIC chemists characterize Alzheimer's neurotoxin structure
Amyloid plaques, the hallmark of Alzheimer's disease, are clumps of fiber-like misfolded proteins which many experts think cause this devastating neurodegenerative disease. view more (2007-12-04)
New collaboration between Amersham Biosciences and Affibody increases potential in protein purification
Under the agreement, the two companies will work to develop affinity-based products for use in the production processes for protein-based pharmaceuticals. The development of these products will be based on Affibodies™, a novel class of small, robust affinity proteins designed to bind desired protein targets. Financial details of the... view more... (2002-03-06)
Aspirin discovery may improve cancer treatments
Salicylates, including aspirin, are used to treat a range of inflammatory conditions and can be used to prevent diseases such as cancer, but the way aspirin works is not yet fully understood. view more (2007-04-06)
Making sense of the human genome: researchers characterize a crucial family of signaling proteins in the human genome
In this month's Genome Biology, Mitch Kostich and colleagues from the Schering-Plough Research Institute (NJ, USA) have identified and mapped an important group of molecules known as protein kinases. These molecules are central to the communication of information both within and between cells, in a process known as cell signaling. Defective... view more... (2002-08-23)
Cold Spring Harbor Protocols features methods for analyzing protein interactions
Cold Spring Harbor Protocols, an online journal that publishes methods used in a wide range of biology laboratories, has added over 40 new peer-reviewed protocols to its archive today. view more (2006-09-11)
BSE in sheep: first estimates of human death toll
Under Strict Embargo for 19:00 GMT / 14:00 US EST Wednesday 9 January 2002 BSE in sheep: first estimates of human death toll The first attempt to estimate the human health risk from possible BSE infection of the British sheep flock is published today by researchers from Imperial College, London. They show that while the present risk of... view more... (2002-01-08)
Microbiology Today: Discovering the secrets of extraordinary life forms
Not long ago, the discovery of viruses revolutionized our thinking about the lower limits of microscopic life. Now even small strands of RNA are found to be infectious in plants, and proteins are believed to cross the species barrier and cause brain disease. In the November 2000 issue of Microbiology Today Nicola Spence and Dez Barbara of... view more... (2000-11-13)
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