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Journal of Alzheimer's Disease is devoted to metal ions and neurodegenerative diseases
The recent issue of the Journal of Alzheimer's Disease (Volume 8, Issue 2) published by IOS Press is devoted to "Metal Ions and Neurodegenerative Diseases" and presents a collection of important papers dedicated to uncovering the role of various metals in human neurophysiology and neurodegenerative disorders. view more (2006-01-13)
Yes-associated protein: Early diagnosis of gastric carcinoma
Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator. view more (2009-09-16)
Scientists isolate protein that may be 'boon' to medicine
Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." view more (2009-08-05)
CSH Protocols publishes cutting-edge methods for analyzing complex molecular interactions
With the genomes of hundreds of organisms now catalogued, one of the next major challenges is to identify proteins and their interactions. view more (2006-10-05)
Roles of S100A2 and p63 in the carcinogenesis of esophageal squamous cell carcinoma
As a member of the S100 family, S100A2 is considered a candidate tumor-suppressor gene. Recently, p63 gene, a new member of the p53 gene family, has been studied in the fields of tumorigenesis, cell apoptosis and tissue growth. view more (2009-09-17)
A novel marker of colorectal carcinoma
The colorectal cancer is thought to be resulted from a combination of environmental factors, diet, lifestyle, chronic inflammation and accumulation of specific genetic alterations. view more (2009-05-22)
Protein splicing upsets the DNA colinearity paradigm
Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. view more (2006-09-08)
Lessons from yeast: A possible cure for Parkinson's disease?
Parkinson disease (PD) is a debilitating and lethal neurodegenerative disease, for which there is currently no cure. It is caused by the progressive loss of nerve cells that produce the chemical dopamine and is characterized by the accumulation of abnormal aggregates of a protein called alpha-syn in these dopaminergic nerve cells. view more (2008-08-15)
Researchers discover a new genetic cause of Alzheimer's disease
Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp are the first to show that the quantity of amyloid protein in brain cells is a major risk factor for Alzheimer's disease. view more (2006-04-20)
U of M researchers determine structure of protein that mutates DNA of the AIDS virus HIV-1
Understanding the structure of proteins involved in inhibiting HIV-1 infection could help in the battle against AIDS, and University of Minnesota researchers have taken a crucial step in that direction. view more (2008-02-21)
NMR advance relies on microscopic detector
Detecting the molecular structure of a tiny protein using nuclear magnetic resonance (NMR) currently requires two things: a million-dollar machine the size of a massive SUV, and a large sample of the protein under study. view more (2007-05-16)
Estrogen protects liver after traumatic injury
Researchers have identified the receptor pathway used by estrogen to decrease liver injury after trauma and hemorrhage. view more (2007-04-02)
Can cancer drugs combine forces?
Individuals with chronic myeloid leukemia (CML) are treated first with a drug known as imatinib (Gleevec), which targets the protein known to cause the cancer (BCR-ABL). view more (2007-08-17)
New Cancer Gene Discovered
Researchers at the OU Cancer Institute have identified a new gene that causes cancer. The ground-breaking research appears Monday in Nature's cancer journal Oncogene. view more (2008-05-09)
Scientists begin to untangle root cause of Alzheimer's disease
"N60" might not be the first thing that comes to mind when people think of Alzheimer's disease, but thanks to researchers from the United States, South Korea and France, this might change. view more (2009-09-04)
New crops needed for new climate
Global food security in a changing climate depends on the nutritional value and yield of staple food crops. Researchers at Monash University in Victoria, Australia have found an increase in toxic compounds, a decrease in protein content and a decreased yield in plants grown under high CO2 and drought conditions. view more (2009-06-29)
Marking anorexia with a brain protein
Eating disorders are frequently seen as psychological or societal diseases, but do they have an underlying biological cause? A new study shows that the levels of a brain protein differ between healthy and anorexic women. view more (2009-06-24)
Fragments of dinosaur protein survive in bone fossils
Proteins are tougher than we think - which is good news for scientists trying to piece together the history of evolution from fragments of ancient DNA. In this month’s (December 2000) edition of the journal, Geology, Dr Matthew Collins, of Newcastle University, England, shows how significant pieces of delicate protein have survived in... view more... (2000-12-18)
Unraveling how cells respond to low oxygen
Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. view more (2009-08-06)
Photonic crystal biosensors detect protein-DNA interactions
Scientists at the University of Illinois have developed a new class of disposable, microplate-based optical biosensors capable of detecting protein-DNA interactions. Based on the properties of photonic crystals, the biosensors are suitable for the rapid identification of inhibitors of protein-nucleic acid and protein-protein interactions. view more (2008-09-24)
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