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Signaling for cartilage
Skeletal progenitor cells differentiate into cartilage cells when one master gene actually suppresses the action of another, said Baylor College of Medicine researchers in a report that appears online in the journal Proceedings of the National Academy of Sciences.   view more (2006-11-28)

Columbia University Medical Center researchers discover potential mechanism for tumor growth
Researchers at Columbia University Medical Center have identified an inherent feature of stem and progenitor cells that may promote initiation and progression of cancerous tumors.   view more (2005-12-16)

Drawing a crowd: How progenitor cells are recruited to tumor blood vessels from the bone marrow
Cells within the bone marrow (progenitor cells) that express a protein called CD34 have been shown to leave the marrow and travel to sites of tissue injury to mediate repair.   view more (2006-02-24)

When is a stem cell not really a stem cell?
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between "true" neural stem cells and similar, but less potent versions.   view more (2007-08-27)

ESC Congress 2004: Embryonic endothelial progenitor cells help overcome myocardial infarction in pigs
Myocardial infarction, caused by coronary artery occlusion, can lead up to loss of muscle tissue of the heart and functional detriment, even at times where rapid reperfusion strategies like PTCA or thrombolysis are at hand. In the study presented here, we investigated embryonic endothelial... view more (2004-08-30)

Cells on path to becoming mature T-cells more flexible than commonly thought
Contrary to the currently accepted model of T-cell development, researchers at the University of Pennsylvania School of Medicine have found that juvenile cells on their way to becoming mature immune cells can develop into either T cells or other blood-cell types versus only being committed to the... view more (2008-04-10)

New research targets treatment for dementia and brain injuries
Queensland Brain Institute (QBI) researchers have identified a process that could lead to development of repair mechanisms for people suffering from dementia and acquired brain injury.   view more (2005-11-29)

Brain size may depend upon how neural cells are cleaved
Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development.   view more (2005-07-15)

Stem cell therapy shows promise for rescuing deteriorating vision
For the millions of Americans whose vision is slowly ebbing due to degenerative diseases of the eye, the lowly neural progenitor cell may be riding to the rescue.   view more (2007-03-28)

Researchers grow human blood vessels in mice from adult progenitor cells
For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors - an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association.   view more (2008-07-21)

Scientists successfully awaken sleeping stem cells
Scientists at Schepens Eye Research Institute have discovered what chemical in the eye triggers the dormant capacity of certain non-neuronal cells to transform into progenitor cells, a stem-like cell that can generate new retinal cells.   view more (2008-03-19)

From lung to gut - the Wnt signaling pathway transforms cell fate
Researchers have uncovered a cellular mechanism that can alter the fate of progenitor cells that normally generate the lung, causing them to create gut cells instead. The findings, which are published this week in the top-tier Open Access journal, Journal of Biology, could help researchers hoping... view more (2004-06-03)

UCLA stem cell researchers create heart and blood cells from reprogrammed skin cells
Stem cell researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been reprogrammed into cells with the same unlimited properties as embryonic stem cells.   view more (2008-04-30)

Stomach stem cell discovery could bring cancer insights
Scientists have identified and described stem cells specific to several tissues and organs of the body - key master cells that give rise to the specialized cell types characteristic of that organ.   view more (2007-10-04)

Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural... view more (2008-02-19)

Penn study finds hyperbaric oxygen treatments mobilize stem cells
According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient's body.   view more (2005-12-29)

New molecular insight into vertebrate brain development
In the December 1st issue of G&D, Dr. Fred H. Gage (The Salk Institute for Biological Studies) and colleagues reveal a role for the Hippo signaling pathway in the regulation of vertebrate neural development, identifying new factors - and potential therapeutic targets - that may be involved in... view more (2008-11-18)

Mass. General researchers identify master cardiac stem cell
Researchers from the Massachusetts General Hospital (MGH) Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major types of cells that make up the mammalian heart.   view more (2006-11-27)

Statins have unexpected effect on pool of powerful brain cells
Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.   view more (2008-07-07)

Neural stem cell gene plays crucial role in eye development
Scientists at the University of North Carolina at Chapel Hill have demonstrated that normal development of the eye requires the right amount of a neural stem cell gene be expressed at the right time and place.   view more (2006-05-16)

New source of heart stem cells discovered
Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells.   view more (2008-06-23)

Gladstone researchers hone in on differentiation of heart stem cells
A team of scientists from the Gladstone Institute of Cardiovascular Disease (GICD) has identified a key factor in heart development that could help advance gene therapy for treating cardiac disorders.   view more (2005-12-16)

Scientists isolate leukemia stem cells in a model of human leukemia
Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston and their colleagues have isolated rare cancer stem cells that cause leukemia in a mouse model of the human disease.   view more (2006-07-18)

Key factor in brain development revealed, offers insight into disorder
In the earliest days of brain development, the brain's first cells - neuroepithelial stem cells -- divide continuously, producing a population of cells that eventually evolves into the various cells of the fully formed brain.   view more (2008-03-27)

Power of Molecular Imaging Reveals Secrets of the Heart
The extraordinary action of a new cellular therapy came to light as a result of powerful PET and SPECT imaging in a recent study reported in the April issue of the Journal of Nuclear Medicine.   view more (2008-04-10)
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