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New information points to safer methadone use for treatment of pain and addiction
New findings may significantly improve the safety of methadone, a drug widely used to treat cancer pain and addiction to heroin and other opioid drugs, according to researchers at Washington University School of Medicine in St. Louis and the University of Washington in Seattle. view more (2009-03-03)
How flesh-eating bacteria attack the body's immune system
"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. view more (2008-08-14)
Super sticky barnacle glue cures like blood clots
Barnacles are a big problem for boats. Adhering to the undersides of vessels, carpets of the crustaceans can increase fuel consumption by as much as 25%. view more (2009-10-16)
The UAB heads a European research project on proteases and pathological processes
A research group of the UAB Institute of Biotechnology and Biomedicine and the UAB Department of Biochemistry and Molecular Biology, directed by Francesc Xavier Avilés, is the coordinator of a European project aimed at studying proteases with fluorescent molecules that allow their monitoring in healthy and pathological situations. view more (2007-07-18)
Viral 'fitness' explains different resistance patterns to aids drugs
Some HIV medications lead to the development of drug-resistant HIV when patients take as few as two percent of their medications. view more (2006-01-11)
Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. view more (2008-03-17)
An effective method to study the pressure of the Sphincter of Oddi
The Sphincter of Oddi (SO) plays a vital role in maintaining the normal bile duct pressure, promoting gallbladder excretion and preventing from reflux. view more (2008-10-24)
LIPODYSTROPHY RISK FROM HIV-1 THERAPY (p 592)
The risk of lipodystrophy (abnormal fat distribution) in HIV-1 individuals undergoing antiretroviral therapy cannot be attributed to one antiretroviral agent, conclude authors of a study in this week's issue of THE LANCET. Lipodystrophy among HIV-1-infected patients receiving antiretroviral therapy was formally described as a clinical entity in... view more... (2001-02-21)
Curacyte awarded a EUR1.2M grant to fund development of Factor Xa inhibitors
Curacyte AG, a Munich-based drug development company, has announced that its wholly owned subsidiary, Curacyte Chemistry GmbH based in Jena, has been awarded a EUR1.2M R&D grant from the German State of Thuringia's Corporate Technology Development Program. The grant will fund the lead optimization and pre-clinical development of the Company's... view more... (2003-10-29)
Casting a wide net to fight coronaviruses
Coronaviruses-the family of viruses that causes the common cold-gained widespread recognition when the deadly severe acute respiratory syndrome, familiarly known as SARS, killed at least 800 people in 2003. view more (2005-09-06)
First results of the Narval trial (ANRS 088)
Patients with HIV infection may develop resistance to one or more of antiretroviral drugs to which they are exposed during treatment. The selection of the most appropriate drugs for switching therapy in patients who have developed resistance, is a difficult challenge. Both, genetic tests that identify mutations in viral genes associated with... view more... (2000-04-21)
Researchers probe enzyme that may lead to new SARS drugs
Researchers at the University of Illinois at Chicago and two other institutions have unraveled the structure of an important new drug target from the virus that causes SARS, severe acute respiratory syndrome. view more (2006-04-05)
SLU Researchers Uncover Direct Evidence on How HIV Invades Healthy Cells
Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV. view more (2005-12-22)
Aids : Effectiveness of antiretroviral therapy demonstrated in Africa
Tritherapies using antiretroviral drugs have proved their worth in industrialized countries in the fight against Aids. However, in Sub-Saharan Africa, where 70 % of people infected with HIV live, access to such treatments is extremely limited. High cost, complicated procedures, combined with inadequate infrastructures for following up patients or... view more... (2002-06-27)
Transplants In HIV Patients Should Proceed But Drug Interactions Can Be Concern, Concludes Research At International Congress Of The Transplantation Society
While historically surgeons have been reluctant to transplant patients with the human immunodeficiency virus (HIV), in recent years, some centers have begun to accept patients with well-controlled HIV as candidates for liver or kidney transplantation. Based on results of three studies from the United States and one from France, which collectively... view more... (2002-08-20)
HIV integrase inhibitor effective for patients beginning antiretroviral treatment
A member of a new class of antiretroviral drugs is safe and effective for patients beginning treatment against HIV, according to researchers who have completed a two-year multisite phase III clinical trial comparing it with standard antiretroviral drugs. view more (2009-08-03)
Softer washable wool
Love the warmth of woollen clothes but dislike having to dry clean them? Europeans will soon get familiar with the advantages of the new biotech process allows wool garments to be washed in water without shrinking or pilling. view more (2005-03-04)
New Stanford list of HIV mutations vital to tracking AIDS epidemic
In a collaborative study with the World Health Organization and seven other laboratories, researchers at the Stanford University School of Medicine have compiled a list of 93 common mutations of the AIDS virus associated with drug resistance that will be used to track future resistance trends throughout the world. view more (2009-03-06)
Misclassified for centuries, medicinal leeches found to be 3 distinct species
Genetic research has revealed that commercially available medicinal leeches used around the world in biomedical research and postoperative care have been misclassified for centuries. view more (2007-04-12)
'Smart' nanoprobes light up disease
Researchers from Rice University's Center for Biological and Environmental Nanotechnology (CBEN) have developed a "smart" beacon hundreds of times smaller than a human cell that is programmed to light up only when activated by specific proteases. view more (2005-08-02)
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