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Carnegie Mellon engineering researchers automate analysis of protein patterns
Carnegie Mellon University's Justin Y. Newberg and Robert F. Murphy have developed a software toolbox that is intended to help bioscience researchers characterize protein patterns in human tissues.   view more (2008-05-13)

Structure of viral harpoon protein reveals how viruses enter cells
A team of Northwestern University researchers has solved the structure of a molecule that controls the ability of viruses of the paramyxovirus family, including the viruses that cause measles, mumps, and many human respiratory diseases, to fuse with and infect human cells.   view more (2006-01-05)

Researchers find mutiple proteins that stick to medical devices
Biomedical engineers at Washington University in St. Louis have found a new role for the blood protein serum amyloid P in the body's response to medical materials, which may help to explain a variety of problems associated with heart-lung bypass, hemodialysis and the use of artificial vascular... view more (2005-10-06)

Poison digs its own grave
Botrytis cinerea (grey mould) has a large arsenal of molecular pumps at its disposal to protect it against toxic substances such as antibiotics, plant defence compounds and fungicides. Dutch researcher Henk-jan Schoonbeek saw how the fungus started to pump out certain toxic substances within just... view more (2004-12-16)

Scientists take next step in understanding potential target for Ovarian cancer treatment
A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth. The discovery of this additional role may lead to diagnostic tools and earlier treatments for ovarian cancer.   view more (2007-07-17)

Researchers shed light on mechanism of action used by anti-cancer drug
Virginia Commonwealth University Massey Cancer Center researchers have uncovered a new mechanism of action of the anti-cancer drug sorafenib, which could stimulate the development of novel regimens in which it is combined with other molecularly targeted agents for patients with blood cancers and... view more (2007-06-12)

Researchers note differences between people and animals on calorie restriction
Calorie restriction, a diet that is low in calories and high in nutrition, may not be as effective at extending life in people as it is in rodents, according to scientists at Washington University School of Medicine in St. Louis.   view more (2008-09-25)

Mapping dynamic Polycomb group proteins during Drosophila development
The developmental passage from a ball of cells to a fruit-fly is a very complicated process involving both temporal and spatial regulation of genes and pathways.   view more (2006-04-20)

New findings shed light to the mechanisms of Parkinson's disease
The findings of Finnish scientists with their multinational collaborators shed light to the mechanisms of Parkinson's disease and early menopause.   view more (2004-09-07)

Study: Fountain of youth for your heart?
An age-related decline in heart function is a risk factor for heart disease in the elderly. While many factors contribute to a progressive age-related decline in heart function, alterations in the types of fuels the heart uses to produce energy also play important roles.   view more (2007-11-05)

Researchers reveal repressor protein blocks neural stem cell development
A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons.   view more (2007-10-11)

Curbing C. difficile's toxin production
As if being admitted to the hospital weren't bad enough, patients, once admitted, are at higher risk of becoming infected with a "superbug" bacterium, Clostridium difficile (C. difficile).   view more (2007-09-06)

CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells.   view more (2007-03-08)

Early-stage gene transcription creates access to DNA
A gene contained in laboratory yeast has helped an international team of researchers uncover new findings about the process by which protein molecules bind to control sequences in genes in order to initiate gene expression, according to findings reported in the journal Nature.   view more (2008-10-07)

A pathway towards cures for Parkinson`s and cancer
Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has... view more (2002-11-01)

Link between Alzheimer's disease and traumatic brain damage clarified
This week scientists of the Flanders Interuniversity Institute for Biotechnology (VIB) will once again publish a breakthrough in their research regarding Alzheimer's disease.   view more (2005-08-04)

Study finds protein is required for human chromosome production
Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes.   view more (2005-10-13)

Liver CRP production linked to atherosclerosis
New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.   view more (2005-09-29)

New technology for boosting vaccine efficiency
One of the most pressing biomedical issues is the development of techniques that increase the efficiency of vaccines. In a paper published on April 24, 2008 in the journal Vaccine, a Massachusetts's biotechnology company, Cure Lab, Inc. has proposed a new technology for anti-viral vaccination.   view more (2008-04-25)

A 20-year study finds no association between low-carb diets and risk of coronary heart disease
Advocates of low-carbohydrate diets, such as the popular Atkins diet, claim that those diets may help prevent obesity and coronary heart disease (CHD).   view more (2006-11-09)

Solving the mystery of mutated proteins and the brain
In some neurological diseases, too much of what is usually a good thing can be bad, said researchers at Baylor College of Medicine in a report in this week's issue of the journal Cell.   view more (2005-08-26)

Signaling protein helps limit damage in heart attack, Jefferson scientists show
Scientists at the Center for Translational Medicine at Thomas Jefferson University in Philadelphia have shown that a specific signaling protein is crucial to protecting the heart and helping it to adapt during a heart attack.   view more (2008-03-24)

Controlling body size by regulating the number of cells
Why are elephants bigger than mice? The main reason is that mice have fewer cells. Research published in Journal of Biology this week uncovers a key pathway that controls the number of cells in an animal, thereby controlling its size. Ernst Hafen and his colleagues from the University of... view more (2003-08-05)

Scientists link fragile X tremor/ataxia syndrome to binding protein in RNA
Scientists have discovered a key protein in the toxic brain pathway that leads to fragile X tremor/ataxia syndrome (FXTAS), an inherited neurodegenerative disorder.   view more (2007-08-16)

Mayo researchers discover HIV dependence on a human protein
Mayo Clinic virologists have discovered that a specific human protein is essential for HIV to integrate into the human genome.   view more (2006-09-08)

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