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Protein analysis methods, viral vectors featured in Cold Spring Harbor Protocols
Many proteins do not function by themselves as stand-alone units. Instead, multiple proteins associate to form larger structures called protein complexes.   view more (2009-05-05)

Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)

Scientists on track for early diagnosis of neurological diseases
Possible treatments for fatal neurodegenerative diseases such as CJD, Alzheimer's, Parkinson's could result from University of Edinburgh research to find out how specific proteins cause deterioration in brain function. The scientists have discovered for the first time that protein 14-3-3 plays a key role in the development of certain brain... view more... (2003-07-01)

Researchers discover architecture for fundamental processes of life
A team of Canadian researchers has completed a massive survey of the network of protein complexes that orchestrate the fundamental processes of life.   view more (2008-05-14)

Mechanism for regulation of growth and differentiation of adult muscle stem cells is revealed
During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue.   view more (2007-12-10)

Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G
Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have identified a previously unknown function of APOBEC3G (A3G), a protein that acts against HIV, a finding that may lead to new approaches for controlling HIV infection.   view more (2006-10-03)

Membrane complexes take flight
Against currently held dogma, scientists at the Universities of Cambridge and Bristol have revealed that the interactions within membrane complexes can be maintained intact in the vacuum of a mass spectrometer. Their research is published in this week's edition of Science Express.   view more (2008-06-13)

The closest look ever at the cell's machines
Today researchers in Germany announce they have finished the first complete analysis of the "molecular machines" in one of biology's most important model organisms: S. cerevisiae (baker's yeast).   view more (2006-01-23)

New study shows antibody-interleukin complexes stimulate immune responses
The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.   view more (2006-02-23)

Advance in understanding cellulose synthesis
Cellulose is a fibrous molecule that makes up plant cell walls, gives plants shape and form and is a target of renewable, plant-based biofuels research.   view more (2009-06-15)

A glimpse at the Earth's crust deep below the Atlantic
Long-term variations in volcanism help explain the birth, evolution and death of striking geological features called oceanic core complexes on the ocean floor, says geologist Dr Bram Murton of the National Oceanography Centre, Southampton.   view more (2009-11-13)

Scientists shed light on the mystery of photosynthesis
Scientists at the University of Sheffield are part of an international team that has become the first to successfully discover how the component parts of photosynthesis fit together within the cell membrane. In a paper, The native architecture of a photosynthetic membrane, published in Nature on 26 August 2004, they describe how the configuration... view more... (2004-08-25)

Keeping amyloid-and Alzheimer's-in check
Researchers have identified a protein that reins in the rogue activity of the molecules that make the amyloid-beta protein-which may prevent normal brain function in people with Alzheimer's disease.   view more (2006-04-27)

Introducing the biology of the future: Researchers at CellZome AG and EMBL publish record-breaking analysis of a cell's proteome
Scientists are calling it "biology of the next generation," and a major step towards transforming information from genome projects into applications such as the discovery of new drugs. Today researchers from Heidelberg have announced the completion of a large-scale study of the "molecular machines" formed by nearly two thousand... view more... (2002-01-08)

Increase in abnormal heart rhythms in shift workers
Shiftwork increases the risk of abnormal heart rhythms, shows research in Occupational and Environmental Medicine. These changes may help to explain why shiftworkers are susceptible to heart disease. Doctors measured changes in heartbeat and variations in heart rate in 49 employees working shifts, including nights, and 22 employees working normal... view more... (2001-09-07)

Chemical industry helped by small invisible tube
Chemists at Utrecht University have developed a catalyst for fine chemistry. Tiny tubes of graphite are the carrier for this catalyst. PhD student Tijmen Ros successfully tested the catalyst with a standard reaction. Fellow researchers are now making the catalyst suitable for the production of cinnamon alcohol, an aromatic substance and... view more... (2002-01-24)

Immune Cell Communication, Cooperation Keys to Hunting Viruses, Jefferson Immunologists Show
Immunologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have used nanotechnology to create a novel 'biosensor' to solve in part a perplexing problem in immunology: how immune system cells called killer T-cells hunt down invading viruses.   view more (2006-10-27)

Pairing Nanoparticles with Proteins
In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles - particles on the order of billionths of a meter - to proteins so as to form sheets of protein-gold arrays.   view more (2007-06-28)

On the Energy Trail: Berkeley Researchers Find New Details Following the Path of Solar Energy During Photosynthesis
Imagine a technology that would not only provide a green and renewable source of electrical energy, but could also help scrub the atmosphere of excessive carbon dioxide resulting from the burning of fossil fuels.   view more (2008-04-28)

Proteomics Center Devises Method for Assigning Probabilities to Human Protein Interactions
The Stowers Institute's Proteomics Center has published a novel method of using normalized spectral counts derived from a series of affinity purifications analyzed by mass spectrometry (APMS) to generate a probabilistic measure of the preference of proteins to associate with one another.   view more (2008-01-25)
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