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HIV isolate from Kenya provides clues for vaccine design
Two simple changes in its outer envelope protein could render the AIDS virus vulnerable to attack by the immune system, according to research from Kenya and the Fred Hutchinson Cancer Research Center published in PLoS Medicine.   view more (2008-01-03)

Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein.   view more (2006-09-01)

How the world watched Huygens
As Huygens parachuted to the surface of Titan in January 2005, a battery of telescopes around the world were watching or listening.   view more (2006-07-28)

New data on "mad cow" disease
A research team at the University of Navarre has detected the presence of the prion protein in the digestive tract of three animal species: the autochthonous Pyrennean cow, in a primate and in rats. This study is the first to describe the exact location of the "healthy" form of the prion... view more (2004-11-16)

Largest study of human 'interactome' reveals a novel way
Discoveries made during the first large-scale analysis of interactions between proteins in our cells hold promise for identifying new genes involved in genetic diseases.   view more (2006-02-27)

Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q,... view more (2003-09-25)

TANGO - towards faster prognosis of Alzheimer's and Parkinson's diseases?
A large number of diseases - including Alzheimer's disease, Parkinson's disease, and mad cow disease - are the result of proteins that erroneously assume the wrong shape, causing them to stick to each other. This phenomenon is perceptible, but up to now it has been difficult to predict. Researchers... view more (2004-09-13)

Researchers report the cloning of a key group of human genes, the protein kinases
Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated. This is true for even the most common class of cancer-associated genes, the protein kinases, which mediate the majority of signaling... view more (2008-05-05)

Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing... view more (2008-11-10)

Therapeutic peptide frees the protein p73 to kill tumor cells
The protein p53 suppresses tumor development by potently inducing tumor cell death, making it an obvious target for anticancer therapeutics.   view more (2007-03-09)

New fuel consumption-cutting product to be trialled by Stagecoach
Cerulean International Limited, the Oxford, UK-based subsidiary of the British nanomaterials company Oxonica Limited, has announced that its new product Envirox is to be commercially evaluated by Stagecoach UK, with a view to adopting the product over Stagecoach's 7000 strong UK bus fleet. Using... view more (2003-10-15)

Exploring the digital Universe with Europe’s Astrophysical Virtual Observatory
A new European initiative called the Astrophysical Virtual Observatory (AVO) is being launched to provide astronomers with a breathtaking potential for new discoveries. It will enable them to seamlessly combine the data from both ground- and space-based telescopes which are making observations of... view more (2001-12-05)

NIST trumps the clumps: Making biologic drugs safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals.   view more (2008-07-24)

Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases,... view more (2008-07-30)

Scientists learn more about how viruses reproduce, spread
Biochemists at Wake Forest University School of Medicine have made a surprising discovery about the inner workings of a powerful virus - a discovery that they hope could one day lead to better vaccines or anti-virus medications.   view more (2006-04-07)

Liver CRP production linked to atherosclerosis
New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis.   view more (2005-09-29)

Mayo Clinic researchers measuring C-reactive protein is early indicator of stiffened arteries
Researchers around the world agree that C-reactive protein is associated with increased risk of heart attack and stroke.   view more (2005-08-24)

Crystal structure enables tailoring of pharmaceuticals against asthma
Researchers at Karolinska Institutet in Sweden have managed to elucidate the crystal structure of a human membrane protein - LTC4 synthase - which has a major influence on the development of asthma.   view more (2007-07-17)

Unfolded proteins may protect cells from dying
When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually serves a protective role; rather than a sign that the cell has given up, it may be a... view more (2006-12-27)

Research To Improve Screening For Warts Linked To Cervical Cancer Risk
Researchers are testing thousands of cervical smear samples to try and identify which types of wart viruses may lead to cancer. They will also examine the benefits of a new form of smear testing. Collaborating scientists and doctors from the University of Edinburgh, Lothian University Hospitals... view more (2002-04-24)

The shape of allergy - what makes an allergen an allergen
An enduring mystery for allergy researchers has been the unpredictable distribution of allergens in plants. For example, being allergic to birch pollen can predispose a person to allergy from distantly related plant foods such as celery, apple or soy.   view more (2005-01-07)

Advance media notice: the EuroScience Open Forum 2004 August 25-28 in Stockholm
The first EuroScience Open Forum meeting will take place in Stockholm August 25-28 2004. It provides a unique opportunity for people interested in science and technology to influence where European science is going and to meet academic and industrial scientists, decision makers from all fields as... view more (2003-06-13)

UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes.   view more (2005-03-16)

Wheat gene may boost foods' nutrient content
Researchers at the University of California, Davis; the U.S. Department of Agriculture; and the University of Haifa in Israel have cloned a gene from wild wheat that increases the protein, zinc and iron content in the grain, potentially offering a solution to nutritional deficiencies affecting... view more (2006-11-27)

Same gene mutation in urinary protein responsible for two different types of kidney disease
The same gene mutation in a urinary protein causes two different types of kidney disease, research in the Journal of Medical Genetics shows.   view more (2002-12-06)
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