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Protein Folding Current Events | Protein Folding News
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Folding Proteins on a Computer
Proteins only function when properly folded In order for enzymatic reactions to proceed correctly, the enzyme and substrate must fit together as precisely as a lock and key. The function of the enzyme and protein is determined by the structure of the latter. The chain of amino acids that makes up the protein thus has to fold in a very precise... view more... (2001-01-19)
Comprehensive model is first to map protein folding at atomic level
Scientists at Harvard University have developed a computer model that, for the first time, can fully map and predict how small proteins fold into three-dimensional, biologically active shapes. view more (2006-11-07)
rotein folding: Building a strong foundation
Like a 1950's Detroit automaker, it appears that nature prefers to build its proteins around a solid, sturdy chassis. view more (2006-09-18)
Folding wings - just the business for insect survival
Just like modern businesses, insects have had to diversify to survive, according to University of York scientist Peter Mayhew. The ability to fold their wings is one device they have adopted over the years as part of the struggle for survival, says Dr Mayhew. And folding wings have given the insects which adopted them - including bugs, beetles,... view more... (2002-05-01)
Unexpected similarities between raindrops and proteins
Raindrops and proteins seem to have a lot in common. This has been shown in a new study by scientists at Ume'å University in Sweden. The principle behind the formation of raindrops is very similar to how proteins fold. This knowledge is vital to our understanding of neurodegenerative diseases like ALS. These findings have been published in... view more... (2004-05-26)
Free-energy theory borne out in large-scale protein folding
In unprecedented new research, scientists at Rice University have combined theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein. view more (2005-10-04)
Caltech and UCSD researchers shed light on how proteins find their shapes
Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show just how amino-acid chains might fold up into unique, three-dimensional functional proteins. view more (2009-02-24)
Decoding protein structures helps illuminate cause of diabetes
Any photographer can vouch for the difficulty of capturing a clear picture of a moving target.
When it comes to molecules, however, sometimes the motion is exactly what scientists want to see - for example, to understand the pathological protein mis-folding and assembly that seem to underlie a host of human disorders, including diabetes and... view more... (2007-05-17)
Water is 'designer fluid' that helps proteins change shape, scientists say
Ubiquitous on Earth, water also has been found in comets, on Mars and in molecular clouds in interstellar space. Now, scientists say this common fluid is not as well understood as we thought. view more (2008-08-07)
Penn biologists discover how 'silent' mutations influence protein production
Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. view more (2009-04-10)
DNA constraints control structure of attached macromolecules
A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. view more (2005-06-29)
Cutting edge - Scientists have combined a cutting ribosyme activity with an unwinding helicase activity
Scientists have long toyed with the idea of putting to work a special class of biological catalysts, called ribozymes, as therapeutic agents. These molecular scissors would harness the activities of overly active genes that contribute to diseases like cancer by cutting their immediate products, messenger RNAs, into unusable pieces. The advantage... view more... (2002-05-10)
Faster protein folding achieved through nanosecond pressure jump
A new method to induce protein folding by taking the pressure off of proteins is up to 100 times faster than previous methods, and could help guide more accurate computer simulations for how complex proteins fold. view more (2009-06-02)
New technology illuminates protein interactions in living cells
While fluorescence has long been used to tag biological molecules, a new technology developed at Yale allows researchers to use tiny fluorescent probes to rapidly detect and identify protein interactions within living cells while avoiding the biological disruption of existing methods, according to a report in Nature Chemical Biology. view more (2007-11-12)
Measuring protein movements with nanosecond resolution
Researchers at the Department of Chemistry at the Technische Universität München (TUM) have developed a method that allows the observation of local movements in proteins on a time scale of nanoseconds to microseconds. view more (2010-03-16)
New computer simulation helps explain folding in important cellular protein
Most parts of living organisms come packaged with ribbons. The ribbons are proteins-chains of amino acids that must fold into three-dimensional structures to work properly. view more (2009-07-30)
Scientists find a biological 'fountain of youth' in new world bat caves
Scientists from Texas are batty over a new discovery which could lead to the single most important medical breakthrough in human history-significantly longer lifespans. view more (2009-07-01)
Engineers study brain folding in higher mammals
Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development. view more (2007-10-02)
Researchers reveal insights into hidden world of protein folding
The proteins upon which life depends share an attribute with paper airplanes: Unless folded properly, they just won't fly. view more (2008-06-12)
Prediction of RNA pseudoknots using heuristic modeling with mapping and sequential folding
An algorithm utilizing structure mapping and thermodynamics is introduced for RNA pseudoknot prediction. The method finds the minimum free energy in the context of the biological folding direction (5' to 3') of RNA sequences. view more (2007-09-19)
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