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Viral oncoprotein inactivation of p53
A group of scientists led by USC researcher Dr. Xiaojiang Chen lend structural insight into tumor suppressor inactivation by a viral oncoprotein.   view more (2006-09-01)

Protein may predict heart attack and early death, not stroke
People with high levels of a protein called C-reactive protein (CRP), a marker for inflammation in the blood, may be at higher risk for heart attack and death but not stroke, according to a study published in the October 20, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.    view more (2009-10-20)

Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q, which contains more than 100 genes. Working with... view more... (2003-09-25)

Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity.   view more (2008-11-10)

Researchers report the cloning of a key group of human genes, the protein kinases
Although the human genome has been sequenced, research into mechanism of action of genes has been hampered by the fact that most human genes have not been isolated. This is true for even the most common class of cancer-associated genes, the protein kinases, which mediate the majority of signaling events in cells by phosphorylating and modulating... view more... (2008-05-05)

NIST trumps the clumps: Making biologic drugs safer
Scientists at the National Institute of Standards and Technology (NIST) have developed a technique to measure the formation of clumps of proteins in protein-based pharmaceuticals.   view more (2008-07-24)

Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published... view more... (2008-07-30)

Scientists learn more about how viruses reproduce, spread
Biochemists at Wake Forest University School of Medicine have made a surprising discovery about the inner workings of a powerful virus - a discovery that they hope could one day lead to better vaccines or anti-virus medications.   view more (2006-04-07)

Giant leap in tiny technology
A £10 million project that aims to put the UK at the forefront of future micro-manufacturing technology is being launched at The University of Nottingham tomorrow.   view more (2005-04-25)

Mayo Clinic researchers measuring C-reactive protein is early indicator of stiffened arteries
Researchers around the world agree that C-reactive protein is associated with increased risk of heart attack and stroke.   view more (2005-08-24)

High protein diet may be bad for women trying to conceive
A moderately high protein diet could reduce a woman's chances of becoming pregnant, according to new research presented at the 20th annual conference of the European Society of Human Reproduction and Embryology today on Monday 28 June. Researchers from the USA have found that a diet containing 25% protein disrupted the normal genetic imprinting... view more... (2004-06-28)

Infections may lead to faster memory loss in Alzheimer's disease
Getting a cold, stomach bug or other infection may lead to increased memory loss in people with Alzheimer's disease.   view more (2009-09-08)

Moderate amounts of protein per meal found best for building muscle
For thousands of years, people have believed that eating large amounts of protein made it easier to build bigger, stronger muscles. Take Milo of Croton, the winner of five consecutive Olympic wrestling championships in the sixth century BC: If ancient writers are to be believed, he built his crushing strength in part by consuming 20 pounds of meat... view more... (2009-10-27)

Crystal structure enables tailoring of pharmaceuticals against asthma
Researchers at Karolinska Institutet in Sweden have managed to elucidate the crystal structure of a human membrane protein - LTC4 synthase - which has a major influence on the development of asthma.   view more (2007-07-17)

Unfolded proteins may protect cells from dying
When cells get stressed, their proteins go unfolded. It's a reaction with a straightforward name: the unfolded protein response. Now, new research from Rockefeller University shows that this phenomenon actually serves a protective role; rather than a sign that the cell has given up, it may be a mechanism by which the cells cope with adversity.   view more (2006-12-27)

Wheat gene may boost foods' nutrient content
Researchers at the University of California, Davis; the U.S. Department of Agriculture; and the University of Haifa in Israel have cloned a gene from wild wheat that increases the protein, zinc and iron content in the grain, potentially offering a solution to nutritional deficiencies affecting hundreds of millions of children around the world.   view more (2006-11-27)

Same gene mutation in urinary protein responsible for two different types of kidney disease
The same gene mutation in a urinary protein causes two different types of kidney disease, research in the Journal of Medical Genetics shows.   view more (2002-12-06)

Ume'å scientist presents discoveries about natural immunity in Science
A team including scientists at UCMP (Ume'å Center for Molecular Pathogenesis), a research unit at Ume'å University, shows in last week's issue of the journal Science that the protein PGRP-LC plays a crucial role in so-called innate immunity. Professor Dan Hultmark, post-doctoral fellow Svenja Stöven, and doctoral candidate Thomas... view more... (2002-03-04)

McMaster University researchers discover zip codes for protein
McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).   view more (2007-01-30)

Scientists locate disease switches
A team of scientists from the University of Copenhagen and the Max Planck Institute in Germany, using groundbreaking technology, has identified no less than 3,600 molecular switches in the human body.    view more (2009-07-17)
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