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New technique boosts by four times the size of a protein that researchers can analyze
Imagine you had to break a secret code, but you could see only part of the message. That's the kind of frustration researchers face when trying to identify proteins and characterize how those proteins are modified in cells by biological processes. view more (2006-10-09)
New open-source software permits faster desktop computer simulations of molecular motion
Whether vibrating in place or taking part in protein folding to ensure cells function properly, molecules are never still. Simulating molecular motions provides researchers with information critical to designing vaccines and helps them decipher the bases of certain diseases, such as Alzheimer's and Parkinson's, that result from molecular motion... view more... (2009-02-05)
Sulfurous ping-pong in the urinary tract
Transfer of information is a basic property of biological systems. Common examples include transfer of genetic information or nerve impulses. view more (2008-12-19)
A new wrinkle in evolution -- Man-made proteins
Nature, through the trial and error of evolution, has discovered a vast diversity of life from what can only presumed to have been a primordial pool of building blocks. view more (2007-05-23)
The sound of proteins
Biologists have converted protein sequences into classical music in an attempt to help vision-impaired scientists and boost the popularity of genomic biology. view more (2007-05-03)
Why don't all moles progress to melanoma?
Everyone has moles. Most of the time, they are nothing but a cosmetic nuisance. But sometimes pigment-producing cells in moles called melanocytes start dividing abnormally to form a deadly form of skin cancer called melanoma. view more (2006-10-03)
Help for bleeding hearts: new research links a third protein to blood-clotting disorders
Studying receptors on the surface of blood platelets, sticky cells that cause blood to clot, has given one Rockefeller researcher new insight into potential causes and treatments for certain cardiovascular diseases. view more (2006-04-20)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-10)
Researchers observe single protein dimers wavering between two symmetrically opposed structures
Researchers at The Scripps Research Institute, the University of California, San Diego, and Ohio State University have used a very sensitive fluorescence technique to find that a bacterial protein thought to exist in one "natural" three-dimensional structure (shape), can actually twist itself into a second form, depending on the... view more... (2009-06-22)
Beyond genes: Lipid helps cell wall protein fold into proper shape
A protein that provides a vital passage through a bacterium's outer cell wall will misfold and malfunction if that wall is built of the 'wrong' material, scientists at The University of Texas Medical School at Houston report in a finding that has long-term implications for understanding diseases caused by misfolded proteins such as cystic... view more... (2005-07-18)
Medical College of Wisconsin discovery alters longstanding concept of fixed protein structure
The thousands of proteins found in nature are simply strings of amino acids, assembled by genes, and scientists have long believed that they automatically fold themselves into uniquely fixed, 3-dimensional shapes to fire the engine of life. view more (2008-03-18)
Protein folding: Diverse methods yield clues
Rice University physicists have written the next chapter in an innovative approach for studying the forces that shape proteins -- the biochemical workhorses of all living things. view more (2009-08-07)
£4 Million for New Centres for Structural Biology
The Biotechnology and Biological Sciences Research Council (BBSRC) today announces its intention to fund four more UK Centres for Structural Biology. view more (1999-02-01)
Ancient protein offers clues to killer condition
More than 600 million years of evolution has taken two unlikely distant cousins - turkeys and scallops - down very different physical paths from a common ancestor. But University of Leeds researchers have found that a motor protein, myosin 2, remains structurally identical in both creatures. view more (2008-05-13)
Scientists identify prion's infectious secret
Researchers have known for decades that certain neurodegenerative diseases, such as mad cow disease or its human equivalent, Cruetzfeldt-Jakob disease, result from a kind of infectious protein called a prion. view more (2007-05-10)
Study reveals mechanism for cancer-drug resistance
Using the worm Caenorhabditis elegans, researchers at UT Southwestern Medical Center have discovered a mechanism by which cancer cells become resistant to a specific class of drugs. view more (2006-10-11)
Folded sediment unusual in Sumatran tsunami area
Sediment folding may have added to the exceptionally large tsunami that struck Sumatra on Dec. 26, 2004, according to an international team of geologists. "Tsunami models consider the rebound of the plate during the earthquake, but do not include permanent deformation, like folding, of the upper plate." says Dr. Donald M. Fisher,... view more... (2007-02-05)
Physics and biology team up to tackle protein folding debate
A team of researchers from EPFL, (Ecole Polytechnique Fédérale de Lausanne), the University of Lausanne, Northwestern University and Tel Aviv University bring biology and statistical physics together to answer the question of how molecular chaperones fold, unfold and pull proteins around in the cell. view more (2006-04-04)
Harvesting "green" pharmaceuticals
Blood substitutes and antibodies to combat caries, harvested from plants - molecular farming provides a solution. Fraunhofer researchers are producing a number of valuable substances from tobacco. They were awarded Joseph-von-Fraunhofer special-merit prize. view more (2001-11-12)
'Intrabody' can mop up mutant protein in Huntington's disease model
Scientists have created a tool for mopping up the clumps of mutant protein that drive neurodegeneration in Huntington's disease. Emory University researchers engineered a virus to make an intracellular antibody or "intrabody" against huntingtin, the protein whose mutant forms poison the brain cells of people with Huntington's. view more (2008-05-27)
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